Infections and Toxins: C. perfringens and Clostridium difficile

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18 Questions

What type of spores are produced by Clostridium species?

Oval or spherical spores

Which Clostridium species is associated with gas gangrene?

Clostridium perfringens

Which toxin causes red blood cell rupture in Clostridium perfringens infections?

Alpha toxin

Which form of food poisoning is associated with Bacillus cereus and fried rice?

Emetic type

What are the usual methods of disinfection for Bacillus cereus?

Ineffective against the pathogen

Which disease caused by Clostridium species is more of an intoxication than a foodborne infection?

Botulism

What is the causative agent of tetanus or lockjaw?

Clostridium tetani

Which toxin is elaborated by Clostridium tetani causing tetanus?

Tetanospasmin

In which patients is Clostridium tetani infection most commonly seen?

IV drug abusers and geriatric patients

What is the main therapy for treating gas gangrene?

Administration of penicillin G

Which type of toxin is produced during Clostridium difficile infection?

Enterotoxin

What is the mechanism of action of Clostridium botulinum toxin?

Neurotoxicity causing muscle paralysis

Which organism produces a terminal spore giving it the characteristic appearance of a 'tennis racket'?

Clostridium tetani

What is the method used to diagnose Clostridium botulinum infection?

Mouse protection tests for botulinum toxin

How is rapid diagnosis of Bacillus anthracis infection done in case of a bioterror attack?

Polymerase chain reaction (PCR)–based assays

What characteristic appearance does Clostridium tetani have?

'Tennis racket' shape

In Clostridium botulinum infection, where is botulinum toxin demonstrable?

In mouse protection tests

What is a rapid diagnostic procedure for Bacillus anthracis infection that detects antigens of the organism in the lesion?

Direct fluorescent antibody test

Learn about the causes, symptoms, and treatments for infections caused by C. perfringens and Clostridium difficile bacteria. Explore how these bacteria produce toxins, leading to conditions like gas gangrene and food poisoning.

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