Podcast
Questions and Answers
What is the term for the ability of a host to avoid infection and reduce harm from an infecting organism?
What is the term for the ability of a host to avoid infection and reduce harm from an infecting organism?
- Virulence
- Pathogenicity
- Immunity
- Resistance (correct)
Which term describes the observable symptoms caused by an infection in a host?
Which term describes the observable symptoms caused by an infection in a host?
- Pathogen Reaction
- Asymptomatic Response
- Incubation Period
- Clinical Manifestation (correct)
What method can be used to reduce the spread of infections?
What method can be used to reduce the spread of infections?
- Increased use of antibiotics
- Avoiding vaccinations
- Wearing non-sterile gloves
- Frequent handwashing (correct)
An infection limited to only one organ or site in a host’s body is referred to as what type of infection?
An infection limited to only one organ or site in a host’s body is referred to as what type of infection?
What is the incubation period in the context of infection?
What is the incubation period in the context of infection?
Which of the following best defines virulence?
Which of the following best defines virulence?
Communicable diseases are infections that can be spread how?
Communicable diseases are infections that can be spread how?
What is a potential outcome of infection aside from observable symptoms?
What is a potential outcome of infection aside from observable symptoms?
What type of vaccine contains toxins or toxoids of a pathogen?
What type of vaccine contains toxins or toxoids of a pathogen?
Which of the following can result from a hypersensitive response to insect venom?
Which of the following can result from a hypersensitive response to insect venom?
Isoimmunity is primarily responsible for which of the following?
Isoimmunity is primarily responsible for which of the following?
What is a common reason for the spread of nosocomial infections?
What is a common reason for the spread of nosocomial infections?
What category of antimicrobial control methods includes using UV light?
What category of antimicrobial control methods includes using UV light?
Which of the following factors does NOT contribute to the effectiveness of an antimicrobial procedure?
Which of the following factors does NOT contribute to the effectiveness of an antimicrobial procedure?
Which method is a physical method used to control microbial growth?
Which method is a physical method used to control microbial growth?
What is the primary purpose of using antiseptics?
What is the primary purpose of using antiseptics?
What type of antibiotics would best be used against a specific pathogen?
What type of antibiotics would best be used against a specific pathogen?
Which of the following is an example of a factor that contributes to the spread of nosocomial infections?
Which of the following is an example of a factor that contributes to the spread of nosocomial infections?
Which infectious organism is commonly associated with post-operative infections?
Which infectious organism is commonly associated with post-operative infections?
In healthcare facilities, which type of isolation is used primarily to protect immunocompromised patients?
In healthcare facilities, which type of isolation is used primarily to protect immunocompromised patients?
Which of the following is a recommended guideline in surgical suites to minimize the spread of infection?
Which of the following is a recommended guideline in surgical suites to minimize the spread of infection?
What type of hypersensitivity response occurs after a prolonged period?
What type of hypersensitivity response occurs after a prolonged period?
What type of infection lasts for a prolonged period, ranging from weeks to several years?
What type of infection lasts for a prolonged period, ranging from weeks to several years?
Which of the following infections is contracted in a hospital or healthcare facility?
Which of the following infections is contracted in a hospital or healthcare facility?
Which term describes an infection without apparent symptoms?
Which term describes an infection without apparent symptoms?
What describes the initial period between the entrance of an infection and the appearance of symptoms?
What describes the initial period between the entrance of an infection and the appearance of symptoms?
Which type of infection results from more than one organism?
Which type of infection results from more than one organism?
What is the typical portal through which pathogens enter the body?
What is the typical portal through which pathogens enter the body?
What term refers to a disease that follows an initial infection as a complication?
What term refers to a disease that follows an initial infection as a complication?
Which bodily secretion plays a role in preventing pathogen colonization in mouths?
Which bodily secretion plays a role in preventing pathogen colonization in mouths?
What is the role of the body's normal flora in preventing infections?
What is the role of the body's normal flora in preventing infections?
Zoonosis refers to diseases that are transmitted to humans from which source?
Zoonosis refers to diseases that are transmitted to humans from which source?
What describes the body's mechanisms to raise skin acidity and cleanse pores?
What describes the body's mechanisms to raise skin acidity and cleanse pores?
Which factor measures the success of an organism upon entering a host's body?
Which factor measures the success of an organism upon entering a host's body?
What is defined as the resolution phase of a disease, leading to recovery or death?
What is defined as the resolution phase of a disease, leading to recovery or death?
Which of the following is NOT considered a common portal of exit for pathogens?
Which of the following is NOT considered a common portal of exit for pathogens?
What is the primary function of cerumen in the ear canal?
What is the primary function of cerumen in the ear canal?
Which immune mechanism involves the competition of normal flora with invading microorganisms?
Which immune mechanism involves the competition of normal flora with invading microorganisms?
What role do lysozymes play in the body's defense?
What role do lysozymes play in the body's defense?
Which type of immunity is gained after contracting a disease?
Which type of immunity is gained after contracting a disease?
How is artificially acquired passive immunity provided?
How is artificially acquired passive immunity provided?
What is the importance of phagocytosis in the immune response?
What is the importance of phagocytosis in the immune response?
Which white blood cell is primarily involved in the initial response to inflammation?
Which white blood cell is primarily involved in the initial response to inflammation?
What is the role of interferon in the immune response?
What is the role of interferon in the immune response?
What occurs during the engulfment stage of phagocytosis?
What occurs during the engulfment stage of phagocytosis?
What is the function of eosinophils in the immune system?
What is the function of eosinophils in the immune system?
Which phase of the interferon response directly prevents the virus from multiplying?
Which phase of the interferon response directly prevents the virus from multiplying?
What role do digestive fluids play in the body's defense mechanisms?
What role do digestive fluids play in the body's defense mechanisms?
What does genetic immunity rely on?
What does genetic immunity rely on?
What is the primary function of cytotoxic T cells?
What is the primary function of cytotoxic T cells?
Which phase follows the lag phase in the antibody-production cycle?
Which phase follows the lag phase in the antibody-production cycle?
What role do suppressor T cells play in the immune response?
What role do suppressor T cells play in the immune response?
What distinguishes activated B cells from inactive B cells?
What distinguishes activated B cells from inactive B cells?
What is the main purpose of the exudation stage in the inflammatory reaction?
What is the main purpose of the exudation stage in the inflammatory reaction?
Which type of vaccine contains live, weakened forms of the target pathogen?
Which type of vaccine contains live, weakened forms of the target pathogen?
In humoral-mediated immunity, what is the role of antibodies?
In humoral-mediated immunity, what is the role of antibodies?
What happens during the sensitization stage of cell-mediated immunity?
What happens during the sensitization stage of cell-mediated immunity?
What is the role of memory B cells after initial exposure to an antigen?
What is the role of memory B cells after initial exposure to an antigen?
What is NOT a stage of phagocytosis?
What is NOT a stage of phagocytosis?
What describes cell-mediated immunity?
What describes cell-mediated immunity?
Which statement about helper T cells is true?
Which statement about helper T cells is true?
What is the function of macrophages in the immune response?
What is the function of macrophages in the immune response?
Flashcards
Virulence
Virulence
The ability of a pathogen to cause harm to a host.
Resistance
Resistance
The body's ability to resist infection or reduce harm caused by pathogens.
Incubation Period
Incubation Period
The time between the moment a pathogen enters a host and when symptoms appear.
Localized Infection
Localized Infection
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Systemic Infection
Systemic Infection
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Communicable Diseases
Communicable Diseases
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Antiseptic Practices
Antiseptic Practices
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Disinfectants
Disinfectants
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Acute Infection
Acute Infection
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Chronic Infection
Chronic Infection
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Latent Infection
Latent Infection
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Mixed Infection
Mixed Infection
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Nosocomial Infection
Nosocomial Infection
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Primary Disease
Primary Disease
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Secondary Disease
Secondary Disease
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Illness Period
Illness Period
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Convalescence or Death
Convalescence or Death
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Portals of Entry
Portals of Entry
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Portals of Exit
Portals of Exit
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Disease Transmission
Disease Transmission
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Carrier
Carrier
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What is the role of cerumen?
What is the role of cerumen?
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What are normal flora and how do they help?
What are normal flora and how do they help?
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How do ciliated membranes protect us from infections?
How do ciliated membranes protect us from infections?
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What is the role of lysozymes in fighting infections?
What is the role of lysozymes in fighting infections?
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How do digestive fluids protect us from infection?
How do digestive fluids protect us from infection?
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Explain how flushing actions protect the body from infections.
Explain how flushing actions protect the body from infections.
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What are protective reflexes and how do they help fight infection?
What are protective reflexes and how do they help fight infection?
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What is immunology?
What is immunology?
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What is genetic immunity?
What is genetic immunity?
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What is naturally acquired active immunity?
What is naturally acquired active immunity?
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What is artificially acquired active immunity?
What is artificially acquired active immunity?
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What is naturally acquired passive immunity?
What is naturally acquired passive immunity?
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What is artificially acquired passive immunity?
What is artificially acquired passive immunity?
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What is the interferon response?
What is the interferon response?
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What is phagocytosis?
What is phagocytosis?
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What is the serum-protein response?
What is the serum-protein response?
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What is a T cell?
What is a T cell?
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What is a B cell?
What is a B cell?
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What do helper T cells do?
What do helper T cells do?
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What are sensitized helper T cells?
What are sensitized helper T cells?
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What are memory T cells?
What are memory T cells?
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What are cytotoxic T cells?
What are cytotoxic T cells?
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What do suppressor T cells do?
What do suppressor T cells do?
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What are inactive B cells?
What are inactive B cells?
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What are activated B cells?
What are activated B cells?
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What are memory B cells?
What are memory B cells?
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What are plasma cells?
What are plasma cells?
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What is cell-mediated immunity?
What is cell-mediated immunity?
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What is humoral-mediated immunity?
What is humoral-mediated immunity?
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What are the stages of humoral-mediated immunity?
What are the stages of humoral-mediated immunity?
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What are the stages of the inflammatory reaction?
What are the stages of the inflammatory reaction?
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What is a nonpathogenic strain vaccine?
What is a nonpathogenic strain vaccine?
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Toxoid
Toxoid
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Hypersensitive Response
Hypersensitive Response
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Allergic Reaction
Allergic Reaction
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Anaphylactic Shock
Anaphylactic Shock
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Immediate Hypersensitivity Response
Immediate Hypersensitivity Response
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Delayed Hypersensitivity Response
Delayed Hypersensitivity Response
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Autoimmunity
Autoimmunity
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Isoimmunity
Isoimmunity
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Antiseptic
Antiseptic
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Broad-spectrum Antibiotic
Broad-spectrum Antibiotic
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Narrow-spectrum Antibiotic
Narrow-spectrum Antibiotic
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Sterilization
Sterilization
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Pasteurization
Pasteurization
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Immediacy of Initial Treatment
Immediacy of Initial Treatment
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Study Notes
Infection, Immunology, and Sanitation
- Infection: Invasion of the body by organisms and the body's reaction to their presence and toxins. It's the presence and multiplication of an organism causing harm or disease to a host.
- Virulence: The ability of an infecting organism to harm a host.
- Resistance: The ability of a host to avoid infection and reduce harm from infecting organisms.
- Symptoms: Infections may or may not cause observable symptoms.
- Incubation Period: The time between infection and symptom appearance.
- Localized Infection: Limited to one organ or site.
- Systemic Infection: Spreads throughout the body.
- Acute Infection: Rapid, severe, and short-lived.
- Chronic Infection: Lasting for weeks to years.
- Latent Infection: No apparent symptoms.
- Mixed Infection: Caused by multiple organisms.
- Nosocomial Infection: Contracted in a healthcare facility.
- Primary Disease: The initial infection in a period of illness.
- Secondary Disease: A subsequent infection or complication from the primary disease.
- Phases of Disease: Incubation, illness, convalescence/death
- Portals of Entry/Exit: Openings in the body where pathogens enter (e.g., breaks in skin, nose, mouth) and leave (e.g., nose, mouth, lesions). Disease spreading from exit to entry.
- Carriers: Hosts who have recovered or are asymptomatic but still transmit the disease.
- Zoonosis: Infections spread from animals to humans.
- Sources of Pathogens:
- Living hosts
- Inanimate objects/materials (contaminated food/water, fomites)
- Normal flora (resident bacteria on/in the body)
- Pathogens in soil/surfaces/contaminated foods.
- Factors Affecting Pathogen Virulence:
- Ability to infect (despite host resistance)
- Invasiveness (ability to enter the host)
- Toxigenicity (toxin production strength/amount)
- Physical Barriers to Infection:
- Perspiration, tears, saliva
- Vaginal secretions, mucus, cerumen
- Normal flora, ciliated membranes
- Lysozymes, digestive fluids, flushing actions
- Protective reflexes
- Immunology: Study of the body's resistance to infection.
- Types of Immunity:
- Genetic/innate
- Naturally acquired active
- Artificially acquired active
- Naturally acquired passive
- Artificially acquired passive
- Defense Mechanisms:
- Interferon response (chemical attack on virus by infected cells)
- Phagocytosis (engulfment by cells)
- Serum-protein response (blood/lymph analyze pathogens to develop immunity)
- Inflammatory reaction (tissue traps pathogens)
- White Blood Cells:
- Neutrophils (initial responders, phagocytosis)
- Lymphocytes (T cells/B cells, recognize/mark/remember pathogens)
- Monocytes (become macrophages, phagocytosis)
- Eosinophils (neutralize toxins)
- Basophils (inflammatory response, allow capillary penetration)
- Stages of Interferon Response: Invasion, Synthesis, Release, Interference, Phagocytosis
- Stages of Phagocytosis: Invagination, Engulfment, Vacuole Formation, Fusing, Release
- T cells/B cells:
- Helper T cells (recognize pathogen antigens, present to B cells)
- Memory T cells (store imprint of pathogen antigens)
- Cytotoxic T cells (rupture infected cells)
- Suppressor T cells (suppress immune response)
- Inactive B cells (until exposed to target pathogen antigen)
- Activated B cells (memory B cells/plasma cells)
- Memory B cells (remember antigen)
- Plasma cells (produce antibodies specific to pathogen)
- Types of Immunity Development: Cell-mediated, Humoral-mediated (antibody-mediated)
- Stages of Cell-Mediated Immunity: Sensitization, Cloning, Pathogen Binding, Cytokine Release, Macrophage Response, Suppression
- Stages of Humoral-mediated Immunity: Sensitization, Cloning, Antibody Production, Macrophage Response, Complement Cascade
- Antibody Production Cycle Phases: Lag phase, Primary response, Secondary response
- Inflammatory Reaction Stages: Constriction, Dilation, Exudation, Barrier Formation
- Types of Vaccines:
- Nonpathogenic strain
- Closely related microorganism
- Attenuated living pathogen
- Killed pathogen
- Extract of pathogen
- Toxoid
- Hypersensitive Response: Excessive immune response to a foreign substance. Allergic reactions. Can result in anaphylactic shock.
- Types of Hypersensitive Responses: Immediate, Delayed, Autoimmunity, Isoimmunity
- Methods to Control Microorganisms:
- Antiseptic, disinfectant, sterilization, pasteurization
- Public health, food preservation, sterile product production, research
- Factors Affecting Antimicrobial Procedure Effectiveness:
- Time of treatment, temperature, concentration, microbe type/number/defense
- Antimicrobial Control Methods: Physical (barrier, heat, cold, drying, radiation, ultrasound, filtration) and Chemical (antiseptic, disinfectant, sterilant).
- Factors Contributing to Nosocomial Infections: Improper hand-washing, antibiotic use, false security, type of surgery/care, caregiver load, facility staffing, immunosuppressive agents
- Organisms Causing Nosocomial Infections: Staphylococcus aureus, Streptococcus species, Escherichia coli, Pseudomonas aeruginosa, Mycobacterium species, HIV, Hepatitis, HPV
- Types of Patient Isolation: Total, Protective, Enteric, Wound/skin, Respiratory, Blood/body fluids
- Precautions in Surgical Suites: Handwashing, PPE use (goggles, masks, gloves), sharps disposal, needle recapping avoidance, sterilization of tools.
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