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Questions and Answers
What is the purpose of the indirect antiglobulin test (IAT) in maternal blood screening?
What is the purpose of the indirect antiglobulin test (IAT) in maternal blood screening?
- To detect maternal antibodies against fetal antigens
- To detect Rh-antigens on RBC surface
- To detect fetal hemoglobin in maternal blood
- To detect Rh-antibodies in maternal blood (correct)
What is mixed with maternal blood in the IAT?
What is mixed with maternal blood in the IAT?
- Fetal blood cells
- Rh-negative RBCs
- Rh-positive RBCs (correct)
- Antibody-coated RBCs
Which of the following is a consequence of detecting anti-Rh antibodies in maternal blood?
Which of the following is a consequence of detecting anti-Rh antibodies in maternal blood?
- The mother is at risk of an allergic reaction
- The mother is at risk of blood clots
- The fetus is at risk of anemia
- The fetus is at risk of hemolytic disease (correct)
What is the primary goal of maternal blood screening in pregnancy?
What is the primary goal of maternal blood screening in pregnancy?
What is the term for the reaction that occurs when Rh-antibodies bind to Rh-antigens on RBCs?
What is the term for the reaction that occurs when Rh-antibodies bind to Rh-antigens on RBCs?
Why is it important to detect Rh-antibodies in maternal blood?
Why is it important to detect Rh-antibodies in maternal blood?
What is the purpose of mixing maternal blood with Rh-positive RBCs in the IAT?
What is the purpose of mixing maternal blood with Rh-positive RBCs in the IAT?
What is the significance of detecting Rh-antibodies in maternal blood during pregnancy?
What is the significance of detecting Rh-antibodies in maternal blood during pregnancy?
What is the primary purpose of performing the IAT test during pregnancy?
What is the primary purpose of performing the IAT test during pregnancy?
Why is RhD-immunoglobulin (RhoGAM) administered to Rh-negative mothers during pregnancy?
Why is RhD-immunoglobulin (RhoGAM) administered to Rh-negative mothers during pregnancy?
During which trimester of pregnancy is the IAT test typically performed?
During which trimester of pregnancy is the IAT test typically performed?
What is the consequence of sensitization in an Rh-negative mother?
What is the consequence of sensitization in an Rh-negative mother?
What is the primary goal of maternal blood screening during pregnancy?
What is the primary goal of maternal blood screening during pregnancy?
What is the name of the test used to detect RhD antibodies in the mother's blood?
What is the name of the test used to detect RhD antibodies in the mother's blood?
What is the role of RhD-immunoglobulin (RhoGAM) in preventing hemolytic disease of the newborn?
What is the role of RhD-immunoglobulin (RhoGAM) in preventing hemolytic disease of the newborn?
Why is it essential to detect RhD antibodies in the mother's blood during pregnancy?
Why is it essential to detect RhD antibodies in the mother's blood during pregnancy?
What is the indication of cell clumping in a blood test?
What is the indication of cell clumping in a blood test?
What is the purpose of the indirect antiglobulin test?
What is the purpose of the indirect antiglobulin test?
What happens during delivery that can trigger Rh incompatibility?
What happens during delivery that can trigger Rh incompatibility?
What is the purpose of maternal blood screening during pregnancy?
What is the purpose of maternal blood screening during pregnancy?
What is the result of an agglutination reaction in a blood test?
What is the result of an agglutination reaction in a blood test?
Why is it important to detect Rh antibodies in maternal blood?
Why is it important to detect Rh antibodies in maternal blood?
What is the name of the test used to detect Rh antibodies in maternal blood?
What is the name of the test used to detect Rh antibodies in maternal blood?
What can happen if an Rh-negative mother is exposed to Rh-positive fetal cells during delivery?
What can happen if an Rh-negative mother is exposed to Rh-positive fetal cells during delivery?
What is the purpose of detecting Rh antibodies in maternal blood during pregnancy?
What is the purpose of detecting Rh antibodies in maternal blood during pregnancy?
What is Rh incompatibility?
What is Rh incompatibility?
Study Notes
Indirect Antiglobulin Test (IAT)
- The IAT test is performed on maternal blood to detect the presence of anti-Rh antibodies.
- The test involves mixing maternal blood with Rh-positive RBCs.
- The IAT test is often performed in the first trimester of pregnancy to detect RhD-immunization.
Rh Incompatibility and Pregnancy
- Rh incompatibility occurs in pregnancy when Rh-negative mothers are exposed to Rh-positive fetal RBCs during delivery.
- This can lead to sensitization and subsequent Rh antibody production.
- RhD-immunoglobulin (RhoGAM) can be given to Rh-negative mothers to reduce the probability of sensitization and subsequent Rh antibody production.
Cell Clumping and Antiglobulin Tests
- Cell clumping indicates the presence of the test antigen on the surface of the red cell.
- Antiglobulin tests are used to detect Rh incompatibility and detect Rh antibodies in maternal blood.
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Description
Quiz on the indirect antiglobulin test (IAT), a laboratory test used to detect antibodies in the blood.
