In-Vivo Method for Vaccine Potency Testing

Regulatory review

In vivo assay (correct)

Pathogen challenge

Immunological testing

To evaluate the standards of efficacy established by national regulatory authorities

To measure the ability of the vaccine to reduce the incidence of the disease (correct)

To assess the immune response in the vaccinated animal

To determine the optimal immune response period

Inoculate the animal with the vaccine and then challenge it with the pathogen

Inoculate the animal with the recommended immunological dose and then challenge both the immunized and control animals with the pathogen (correct)

Inoculate the animal with the pathogen and then challenge it with the vaccine

Inoculate the animal with the recommended immunological dose and then monitor its immune response

<p>To evaluate the quality of the vaccine (B)</p> Signup and view all the answers

<p>To assess the pathogenesis caused by the pathogen in the absence of the vaccine (B)</p> Signup and view all the answers