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In-Vitro Dissolution Studies

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Biopharmaceutics lab 4 In vitro dissolution study of oral tablet Drug ______

dissolution

The ______ test: is an in-vitro test for measuring the time required for a given percentage of the drug substance in a tablet to go into solution under a specified set of conditions.

dissolution

When drug is slightly soluble the rate limiting factor for absorption is ______

dissolution

The dissolution test is an important quality control procedure used to: confirm batch-to-batch ______.

reproducibility Signup and view all the answers

A number of formulation and manufacturing factors can affect the disintegration and ______ of a tablet , including Particle size of drug substance.

dissolution Signup and view all the answers

What is the purpose of the dissolution test?

The purpose of the dissolution test is to measure the time required for a given percentage of the drug substance in a tablet to go into solution under specific conditions. Signup and view all the answers

What is the rate limiting factor for absorption when the drug is slightly soluble?

When the drug is slightly soluble, the rate limiting factor for absorption is dissolution. Signup and view all the answers

How are dissolution and drug release tests used as a measure of drug product performance?

Dissolution and drug release tests are used as a measure of drug product performance in vitro when linked to product performance in vivo. Signup and view all the answers

What are some factors that can affect the disintegration and dissolution of a tablet?

Some factors that can affect the disintegration and dissolution of a tablet include the particle size of the drug substance and formulation and manufacturing factors. Signup and view all the answers

What are the two rate limiting factors for absorption?

The rate limiting factors for absorption are dissolution for slightly soluble drugs, and permeability for highly soluble drugs. Signup and view all the answers

In-Vitro Dissolution Studies

Choose a study mode

Podcast

Questions and Answers

Biopharmaceutics lab 4 In vitro dissolution study of oral tablet Drug ______

The ______ test: is an in-vitro test for measuring the time required for a given percentage of the drug substance in a tablet to go into solution under a specified set of conditions.

When drug is slightly soluble the rate limiting factor for absorption is ______

The dissolution test is an important quality control procedure used to: confirm batch-to-batch ______.

A number of formulation and manufacturing factors can affect the disintegration and ______ of a tablet , including Particle size of drug substance.

What is the purpose of the dissolution test?

What is the rate limiting factor for absorption when the drug is slightly soluble?

How are dissolution and drug release tests used as a measure of drug product performance?

What are some factors that can affect the disintegration and dissolution of a tablet?

What are the two rate limiting factors for absorption?

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