Importance of Laboratory Medicine

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31 Questions

Which of the following is NOT an importance of Laboratory Medicine as mentioned in the text?

Excluding nonfunctioning waste products

Which category do substances like Glucose, Cholesterol, and Vitamins fall into according to the text?

Substances normally present with a function in the circulation

What type of lab request would typically have a TURN AROUND TIME of less than one hour according to the text?

"STAT" STATIM/ IMMEDIATE/ URGENT/ EMERGENCY

What is the primary focus of Quality Assurance in Laboratory Medicine according to the text?

Reporting and interpretation of results

Which statement accurately describes the role of clinically significant enzymes according to the text?

Released from cells due to damage or abnormal cellular proliferation

What is the main purpose of screening lab TURN AROUND TIME as stated in the text?

To quickly deliver results for STATIM/IMMEDIATE/URGENT/EMERGENCY requests

What does diagnostic sensitivity measure?

The proportion of individuals with the disease who test positively with the test

Which type of errors are caused by improperly calibrated analytical systems?

Systematic Errors

What is the focus of the analytic phase in Quality Control?

Reliability of lab results

What characteristic describes accuracy in laboratory testing?

Closeness to the true value

What is the role of control specimens in laboratory testing?

To calibrate an assay method and ensure precision

What is the main difference between diagnostic sensitivity and specificity?

Sensitivity measures the ability to correctly identify individuals with the disease, while specificity measures those without the disease.

What is the diagnostic criteria for diabetes according to the American Diabetes Association?

RBS > 200mg/dl on 2 different occasions with symptoms

Which type of diabetes is characterized by autoimmune destruction of pancreatic islet β-cells?

Type 1 diabetes

What markers are commonly found in 85-90% of patients with Type 1 diabetes?

Islet cell autoantibodies

What is the characteristic feature of Impaired Fasting Glucose?

FBS between 110-125mg/dL

What is the main treatment approach for Type 1 diabetes?

Insulin therapy

What distinguishes Sadl Impaired Fasting Glucose and Sadl Impaired Glucose Tolerance from full-blown diabetes?

High blood glucose levels above normal but not diabetic range

What is the Fearon's reaction commonly used for?

Condensation with Diacetyl Monoxime Method

In the context of Azotemia, what does pre-renal Azotemia result from?

Reduced renal blood flow

What is the main cause of Renal Azotemia?

Acute or chronic renal failure

What is the direct method used for in Urea determination?

Measuring urea as a whole

Post-Renal Azotemia is due to obstruction in which part of the body?

Bladder or prostate tumors

What is the main consequence of Uremia or Uremic Syndrome if left untreated?

Increased urea in the blood with renal failure

Which method is also known as the Xanthydrol method?

Fearon’s reaction

What method is used for the measurement of L-Glutamate Dehydrogenase?

GLDH method

In the UREASE-Conductimetric Method, what is the end product when urea is broken down by urease?

HCO3- + NH4+

What is the purpose of Creatinine measurement?

To determine kidney function sufficiency

How is the progression of kidney disease monitored?

By measuring creatinine levels

What specimen considerations are mentioned in the text for testing purposes?

Plasma without citrate or fluoride as anticoagulant

Which method uses ionization and isotopically labelled compound reference for quantification?

IDMS

Learn about the significance of laboratory medicine in confirming diagnoses, excluding conditions, optimizing treatments, providing prognoses, and more. Explore how it helps in screening for diseases and monitoring their severity.

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