Importance of Laboratory Medicine

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Questions and Answers

Which of the following is NOT an importance of Laboratory Medicine as mentioned in the text?

  • Providing a prognosis
  • Confirming a clinical suspicion diagnosis
  • Establishing and monitoring the severity of a physiological disturbance
  • Excluding nonfunctioning waste products (correct)

Which category do substances like Glucose, Cholesterol, and Vitamins fall into according to the text?

  • Substances normally present with a function in the circulation (correct)
  • Substances being cleared in the process
  • Nonfunctioning waste products
  • Substances released from cells due to damage

What type of lab request would typically have a TURN AROUND TIME of less than one hour according to the text?

  • "PRIORITY" for clinical decision-making
  • "ROUTINE" Non-urgent; standard tests, special tests
  • "STAT" STATIM/ IMMEDIATE/ URGENT/ EMERGENCY (correct)
  • "QUALITY MANAGEMENT" Quality Assurance

What is the primary focus of Quality Assurance in Laboratory Medicine according to the text?

<p>Reporting and interpretation of results (C)</p> Signup and view all the answers

Which statement accurately describes the role of clinically significant enzymes according to the text?

<p>Released from cells due to damage or abnormal cellular proliferation (B)</p> Signup and view all the answers

What is the main purpose of screening lab TURN AROUND TIME as stated in the text?

<p>To quickly deliver results for STATIM/IMMEDIATE/URGENT/EMERGENCY requests (D)</p> Signup and view all the answers

What does diagnostic sensitivity measure?

<p>The proportion of individuals with the disease who test positively with the test (A)</p> Signup and view all the answers

Which type of errors are caused by improperly calibrated analytical systems?

<p>Systematic Errors (B)</p> Signup and view all the answers

What is the focus of the analytic phase in Quality Control?

<p>Reliability of lab results (D)</p> Signup and view all the answers

What characteristic describes accuracy in laboratory testing?

<p>Closeness to the true value (D)</p> Signup and view all the answers

What is the role of control specimens in laboratory testing?

<p>To calibrate an assay method and ensure precision (D)</p> Signup and view all the answers

What is the main difference between diagnostic sensitivity and specificity?

<p>Sensitivity measures the ability to correctly identify individuals with the disease, while specificity measures those without the disease. (D)</p> Signup and view all the answers

What is the diagnostic criteria for diabetes according to the American Diabetes Association?

<p>RBS &gt; 200mg/dl on 2 different occasions with symptoms (B)</p> Signup and view all the answers

Which type of diabetes is characterized by autoimmune destruction of pancreatic islet β-cells?

<p>Type 1 diabetes (D)</p> Signup and view all the answers

What markers are commonly found in 85-90% of patients with Type 1 diabetes?

<p>Islet cell autoantibodies (D)</p> Signup and view all the answers

What is the characteristic feature of Impaired Fasting Glucose?

<p>FBS between 110-125mg/dL (B)</p> Signup and view all the answers

What is the main treatment approach for Type 1 diabetes?

<p>Insulin therapy (D)</p> Signup and view all the answers

What distinguishes Sadl Impaired Fasting Glucose and Sadl Impaired Glucose Tolerance from full-blown diabetes?

<p>High blood glucose levels above normal but not diabetic range (B)</p> Signup and view all the answers

What is the Fearon's reaction commonly used for?

<p>Condensation with Diacetyl Monoxime Method (D)</p> Signup and view all the answers

In the context of Azotemia, what does pre-renal Azotemia result from?

<p>Reduced renal blood flow (D)</p> Signup and view all the answers

What is the main cause of Renal Azotemia?

<p>Acute or chronic renal failure (B)</p> Signup and view all the answers

What is the direct method used for in Urea determination?

<p>Measuring urea as a whole (C)</p> Signup and view all the answers

Post-Renal Azotemia is due to obstruction in which part of the body?

<p>Bladder or prostate tumors (A)</p> Signup and view all the answers

What is the main consequence of Uremia or Uremic Syndrome if left untreated?

<p>Increased urea in the blood with renal failure (C)</p> Signup and view all the answers

Which method is also known as the Xanthydrol method?

<p>Fearon’s reaction (B)</p> Signup and view all the answers

What method is used for the measurement of L-Glutamate Dehydrogenase?

<p>GLDH method (D)</p> Signup and view all the answers

In the UREASE-Conductimetric Method, what is the end product when urea is broken down by urease?

<p>HCO3- + NH4+ (B)</p> Signup and view all the answers

What is the purpose of Creatinine measurement?

<p>To determine kidney function sufficiency (C)</p> Signup and view all the answers

How is the progression of kidney disease monitored?

<p>By measuring creatinine levels (B)</p> Signup and view all the answers

What specimen considerations are mentioned in the text for testing purposes?

<p>Plasma without citrate or fluoride as anticoagulant (C)</p> Signup and view all the answers

Which method uses ionization and isotopically labelled compound reference for quantification?

<p>IDMS (A)</p> Signup and view all the answers

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