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Questions and Answers
A pharmacist needs to convert 5 pounds (avoirdupois) into grains. Which calculation is correct based on the avoirdupois system?
A pharmacist needs to convert 5 pounds (avoirdupois) into grains. Which calculation is correct based on the avoirdupois system?
- $5 \times 16$
- $5 \times 7000$ (correct)
- $5 \times 12 \times 5760$
- $5 \times 12$
A formula requires 2.5 liters of a solution. What is this volume equivalent to in microliters?
A formula requires 2.5 liters of a solution. What is this volume equivalent to in microliters?
- 2,500,000 microliters (correct)
- 25,000 microliters
- 2,500 microliters
- 250,000 microliters
A prescription calls for a 10% (w/v) solution of a drug. How many grams of the drug are needed to prepare 500 ml of this solution?
A prescription calls for a 10% (w/v) solution of a drug. How many grams of the drug are needed to prepare 500 ml of this solution?
- 10 grams
- 50 grams (correct)
- 100 grams
- 25 grams
Which of the following is NOT a unit of measure in the Imperial system?
Which of the following is NOT a unit of measure in the Imperial system?
If you need to convert 3 meters into millimeters, which conversion factor would you use?
If you need to convert 3 meters into millimeters, which conversion factor would you use?
A pharmacist is preparing a prescription that requires 2 fluid ounces of a liquid. How many minims are in 2 fluid ounces?
A pharmacist is preparing a prescription that requires 2 fluid ounces of a liquid. How many minims are in 2 fluid ounces?
What is the primary standard of weight (mass) in the apothecary system?
What is the primary standard of weight (mass) in the apothecary system?
You have a 5% (v/v) solution. How many mL of active ingredient are present in 50 mL of the solution?
You have a 5% (v/v) solution. How many mL of active ingredient are present in 50 mL of the solution?
To prepare 250 ml of a 0.5% (w/v) solution of sodium chloride (NaCl) in water, how many grams of NaCl are needed?
To prepare 250 ml of a 0.5% (w/v) solution of sodium chloride (NaCl) in water, how many grams of NaCl are needed?
A pharmacist needs to create 500g of a 5% (w/w) zinc oxide ointment using zinc oxide powder and a petroleum jelly base. How much zinc oxide powder is required?
A pharmacist needs to create 500g of a 5% (w/w) zinc oxide ointment using zinc oxide powder and a petroleum jelly base. How much zinc oxide powder is required?
To prepare 1 liter of a 10% (v/v) solution of ethanol in water, how many milliliters of ethanol are needed?
To prepare 1 liter of a 10% (v/v) solution of ethanol in water, how many milliliters of ethanol are needed?
A prescription requires 2 tablespoonfuls of a medication to be taken every 6 hours. What is the total volume, in milliliters, of medication taken in a day?
A prescription requires 2 tablespoonfuls of a medication to be taken every 6 hours. What is the total volume, in milliliters, of medication taken in a day?
A doctor prescribes 40 grains of a specific medication. How many grams of the medication are required?
A doctor prescribes 40 grains of a specific medication. How many grams of the medication are required?
A formula requires 8 fluid ounces of a particular liquid. How many milliliters of the liquid are needed?
A formula requires 8 fluid ounces of a particular liquid. How many milliliters of the liquid are needed?
A patient weighs 154 pounds. What is the patient's approximate weight in kilograms?
A patient weighs 154 pounds. What is the patient's approximate weight in kilograms?
A doctor orders a 500 microgram dose of a drug. The drug is available as 0.25 mg tablets. How many tablets are required for the prescribed dose?
A doctor orders a 500 microgram dose of a drug. The drug is available as 0.25 mg tablets. How many tablets are required for the prescribed dose?
Flashcards
The Imperial System
The Imperial System
An older system using units like inches, ounces, feet, pounds and gallons.
Avoirdupois System
Avoirdupois System
A system of weights using pounds (lb) as the standard unit of mass.
Apothecary System
Apothecary System
A system of weights and measures originally used for dispensing medications, using grains (gr) as the standard.
The Metric System
The Metric System
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Meter Conversion
Meter Conversion
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Liter Conversion
Liter Conversion
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Gram Conversion
Gram Conversion
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Weight in Volume (w/v)
Weight in Volume (w/v)
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Weight in Weight (w/w)
Weight in Weight (w/w)
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Volume in Volume (v/v)
Volume in Volume (v/v)
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1 Drop (metric)
1 Drop (metric)
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1 Teaspoonful (metric)
1 Teaspoonful (metric)
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1 Tablespoonful (metric)
1 Tablespoonful (metric)
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1 Ounce (apoth)
1 Ounce (apoth)
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1 Grain
1 Grain
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Study Notes
Weights and Measures
- There are two main systems of weights and measures: the Imperial System and the Metric System.
The Imperial System
- This system is an older system of weights and measures.
- It includes units like inches, ounces, feet, pounds, cups, gallons, miles, and tons.
- Weight measures the gravitational force on a body and is proportional to its mass.
- The imperial system has two variations: Avoirdupois and Apothecary.
Avoirdupois System
- A measurement system of weights that uses pounds and ounces as units.
- In this system, the pound (lb) is the standard unit of weight.
- 1 pound avoir (lb) equals 16 ounces (oz).
- 1 pound avoir (lb) also equals 7000 grains (gr).
Apothecary or Troy System
- The apothecary system originated as a system for dispensing and prescribing medications.
- In this system, the grain (gr) is the standard unit of weight(mass).
- 1 pound apoth (lb) equals 12 ounces.
- 1 pound apoth (lb) also equals 5760 grains.
Measurements of Volumes
- 1 gallon (c) equals 4 quarts.
- 1 quart equals 2 pints.
- 1 pint equals 20 fluid ounces.
- 1 fluid ounce equals 8 fluid drachms.
- 1 fluid drachm equals 3 fluid scruples.
- 1 fluid scruple equals 20 minims.
The Metric System
- A system of measurement invented by the French in 1790.
- Also called the International System of Units and is the most used system of measurement on earth.
- Common units include:
- Length: Meter
- Volume: Liter
- Weight: Kilogram
Measure of Length
- 1 meter (1m) equals 100 centimeters.
- 1 meter (1m) equals 1000 millimeters.
- 1 meter (1m) equals 1,000,000 micrometers.
- 1 meter (1m) equals 1,000,000,000 nanometers.
Measure of Volume
- 1 liter (L) equals 1000 milliliters.
- 1 liter (L) equals 1,000,000 microliters (µL).
Measure of Weight
- 1 gram (g) equals 1000 milligrams (mg).
- 1 gram (g) equals 1,000,000 micrograms (µg).
Percentage Solutions
- A percentage is the number of parts per 100.
- The concentration of a substance can be expressed in three types of percentages:
- Weight in volume (w/v): grams of active ingredient in 100 ml of liquid.
- Weight in weight (w/w): grams of active ingredient in 100 g of mixture.
- Volume in volume (v/v): ml volume of active ingredient in 100 ml of liquid.
- In each case, concentration in percentage is calculated as the fraction of the volume/weight of the solute related to the total volume/weight of the solution.
Weight in Volume (w/v)
- Solute: 1 part by weight
- Solvent: 100 parts by volume
- The general formula for 1% (w/v) is:
- Solute: 1 g
- Solvent: up to 100 ml
Example 1
- To calculate the amount of potassium permanganate needed to prepare 250mL of a 0.02%(mg/mL) solution, use a proportion.
-
- 02% means 0.02 mg in 100 ml, so x mg is needed for 250 ml.
- X = (250 x 0.02) / 100, which equals 0.05 mg.
Example 2
- To determine how many milligrams of neomycin are in 50 ml of a 1% mg/ml neomycin solution, set up a proportion.
- If every 100 ml of the solution contains 1 mg of neomycin, then x mg is in 50 ml
- X= (50×1)/100 = 0.5mg
Weight in Weight (w/w)
- Solute: 1 part by weight
- Solvent: 100 parts by weight
- The general formula for 1% (w/w) is:
- Solute: 1 g
- Solvent: up to 100 g
Example
- 20 g of NaCl added to enough sand to make 200 g of mixture results in a 10% (w/w) NaCl/sand mixture.
Volume in Volume (v/v)
- Solute: 1 part by volume
- Solvent: 100 parts by volume
- Formula for 1% (v/v):
- Solute: 1 ml
- Solvent: up to 100 ml
Example
- To find out how many ml of liquid phenol should be used to prepare 240 ml of 2.5% liquid phenol in calamine lotion, use a proportion.
- If there are 2.5 ml of liquid phenol in 100 ml, then x ml is needed for 240 ml.
- X = (2.5 x 240) / 100, which equals 6 ml.
Conversion Table
- 1 drop (domestic) = 0.06ml (metric) = 1 minim (imperial).
- 1 teaspoonful (domestic) = 5 ml (metric) = 1 fluid drachm (imperial).
- 1 desert spoonful (domestic) = 8 ml (metric) = 2 fluid drachm (imperial).
- 1 tablespoonful (domestic) = 15 ml (metric) = 4 fluid drachms (imperial).
- 1 wineglassful (domestic) = 60 ml (metric) = 2 fluid ounces (imperial).
- 1 teacupful (domestic) = 120 ml (metric) = 4 fluid ounces (imperial).
- 1 tumblerful (domestic) = 240ml (metric) = 8 fluid ounces (imperial).
Weight Measure Conversion
- 1 kg equals 2.2 pounds (lb).
- 1 ounce apoth equals 30 g.
- 1 pound avoir equals 450 g.
- 1 grain equals 65 mg.
Conversion Equivalents Weight Table
- 1 gram (g) = 15.432 grains (gr)
- 1 kilogram (kg) = 2.20 pounds (Avoir)
- 1 grain = 64.8 mg (65 or 60 mg)
- 1 ounce (oz) (Avoir) = 28.35 grams
- 1 ounce (â„¥) (Apoth) = 31.1 grams
- 1 pound (Avoir) = 454 grams
- 1 pound (Apoth) = 373 grams
- 1 pound (Avoir) = 7000 grains
- 1 pound (lb) (Apoth) = 5760 grains
- 1 grain Apothecary = 1 grain Avoirdupois
Example
- A prescription needs a dose of 30 grains of a drug.
- To convert to grams: 1 grain = 65mg.
- Therefore, 30 grains = 30 x 65 = 1950mg = 2g.
Example
- If 5 fluid ounces of a liquid is needed, convert to ml.
- 1 fl oz = 30 ml, so 5 fl oz = 5 x 30 = 1500 ml.
Example
- To convert a patient's weight of 12 stones 6 pounds to kg: 1 stone = 14 lb.
- First, calculate total weight in pounds: (12 x 14) + 6 = 174 lb.
- Then, convert to kg: 1kg = 2.2lb, so 174/2.2 = 79.01 kg.
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