Immunology & Serology Review

Which complement protein initiates pore formation on the membrane during the activation of the membrane attack complex (MAC)?

A patient with recurrent Neisseria infections is most likely deficient in which of the following complement components?

Which of the following hypersensitivity reactions involves the formation of immune complexes that activate complement, leading to neutrophil recruitment and tissue damage?

Anaphylaxis, allergic asthma, and food allergies are all examples of which type of hypersensitivity reaction?

Which of the following is the primary mechanism of tissue damage in Type II hypersensitivity reactions?

Contact dermatitis is mediated by what type of hypersensitivity reaction?

In the regulation of thyroid hormones, what is the effect of increased T3 and T4 levels on the release of TSH (Thyroid Stimulating Hormone) from the pituitary gland?

In Myasthenia Gravis, the autoantibodies are directly blocking which of the following?

Laboratory findings reveal a patient's serum sample causes agglutination of IgG-sensitized red blood cells. This indicates the presence of which of the following?

In direct agglutination tests, which of the following serves as the natural carrier of the antigen?

What is the purpose of performing a washing step in AHG-mediated agglutination reactions?

In a serological assay, it is observed that very tiny agglutinates are present, along with many free cells, and the supernatant appears dark and turbid. According to the grading of agglutination, which grade would be appropriate?

After performing a serial dilution, the last tube showing a positive result for a particular antibody is tube number 7. If each dilution is a two-fold dilution, what is the titer of the antibody?

A laboratory conducts a test for a specific disease. The sensitivity of the test is found to be 90%. What does this sensitivity indicate?

Which of the following is added to each well in performing enzyme-linked immunosorbent assay (ELISA)?

What is the major difference between fluorescence polarization immunoassay (FPIA) and ELISA

Which of the following tumor markers is most useful for detecting ovarian cancer?

In patients with DiGeorge syndrome, what type of immunodeficiency is most commonly observed?

A patient's serum is mixed with a sample containing a known antigen, and a precipitin line forms. Both antigen and antibody are diffusing, in which type of immunodiffusion is being performed?

What type of hypersensitivity demonstrates the use of Ag-sensitized Th1 cells release cytokines that recruit macrophages and induce inflammation?