18 Questions
Which type of immune cells are responsible for producing IL-2?
T helper cells
What is the primary function of MHCI molecules in antigen presentation?
To present peptides derived from intracellular viral pathogens to CD8+ T cells
What is the primary function of MHCII molecules in antigen presentation?
To present peptides derived from extracellular pathogens to CD4+ T cells
Which of the following statements about passive immunization is correct?
It can be an immediate treatment against tetanus toxins
Which of the following statements about antigen presentation is true?
Intracellular viral pathogens are degraded by proteasome, producing 8-10 amino acid long peptides that are bound to MHCI molecules in the lumen of the ER and transported to the cell surface of infected cells
Which of the following statements about antigen presentation is true?
Extracellular pathogens are engulfed, degraded by cellular proteases, and could be presented on MHCI molecules in some subsets of dendritic cells
What is the role of MHCI molecules in antigen presentation?
MHCI molecules bind and present peptides derived from intracellular viral pathogens to CD8+ T cells.
What is the role of MHCII molecules in antigen presentation?
MHCII molecules bind and present peptides derived from extracellular pathogens to CD4+ T cells.
Which of the following is NOT a requirement for successful antigen presentation?
Antigen recognition by T cells
Which motif is involved in triggering IL-2 production?
ITAM
What is a key function of dendritic cells in antigen presentation?
Dendritic cells take up antigens in peripheral tissues and migrate to the lymph nodes to present them to T cells.
What is the primary function of antigen processing in the context of antigen presentation?
To generate 8-10 amino acid long peptides from intracellular viral pathogens that can be loaded onto MHCI molecules.
What is the primary function of MHC I molecules?
To present endogenous antigens to CD8+ T cells
What is the role of co-stimulatory signals in T cell activation?
They are required in addition to the antigen-specific signal for full T cell activation
Which cells are considered professional antigen-presenting cells (APCs)?
Dendritic cells, macrophages, and B cells
What is the primary function of MHC II molecules?
To present exogenous antigens to CD4+ T cells
Which cytokine is primarily responsible for promoting T cell proliferation and differentiation?
Interleukin-2 (IL-2)
What is the role of tetanus toxin in the pathogenesis of tetanus?
It inhibits neurotransmitter release, causing muscle spasms
Test your knowledge of antigen-recognizing receptors and passive immunization in immunology with this quiz. Identify cells with specific receptors and understand the concept of passive immunization. Choose the correct answers to enhance your understanding of these immunological processes.
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