Immunology Quiz: Antigen Recognition and Passive Immunization
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Questions and Answers

Which type of immune cells are responsible for producing IL-2?

  • T helper cells (correct)
  • Natural killer cells
  • Mast cells
  • Dendritic cells

What is the primary function of MHCI molecules in antigen presentation?

  • To present peptides derived from intracellular viral pathogens to CD8+ T cells (correct)
  • To transport vesicle-derived peptides to the cell surface of antigen-presenting cells
  • To bind and present IL-2 to T helper cells
  • To present peptides derived from extracellular pathogens to CD4+ T cells

What is the primary function of MHCII molecules in antigen presentation?

  • To present peptides derived from intracellular viral pathogens to CD8+ T cells
  • To present peptides derived from extracellular pathogens to CD4+ T cells (correct)
  • To transport vesicle-derived peptides to the cell surface of antigen-presenting cells
  • To bind and present IL-2 to T helper cells

Which of the following statements about passive immunization is correct?

<p>It can be an immediate treatment against tetanus toxins (C)</p> Signup and view all the answers

Which of the following statements about antigen presentation is true?

<p>Intracellular viral pathogens are degraded by proteasome, producing 8-10 amino acid long peptides that are bound to MHCI molecules in the lumen of the ER and transported to the cell surface of infected cells (D)</p> Signup and view all the answers

Which of the following statements about antigen presentation is true?

<p>Extracellular pathogens are engulfed, degraded by cellular proteases, and could be presented on MHCI molecules in some subsets of dendritic cells (B)</p> Signup and view all the answers

What is the role of MHCI molecules in antigen presentation?

<p>MHCI molecules bind and present peptides derived from intracellular viral pathogens to CD8+ T cells. (D)</p> Signup and view all the answers

What is the role of MHCII molecules in antigen presentation?

<p>MHCII molecules bind and present peptides derived from extracellular pathogens to CD4+ T cells. (D)</p> Signup and view all the answers

Which of the following is NOT a requirement for successful antigen presentation?

<p>Antigen recognition by T cells (C)</p> Signup and view all the answers

Which motif is involved in triggering IL-2 production?

<p>ITAM (A)</p> Signup and view all the answers

What is a key function of dendritic cells in antigen presentation?

<p>Dendritic cells take up antigens in peripheral tissues and migrate to the lymph nodes to present them to T cells. (A)</p> Signup and view all the answers

What is the primary function of antigen processing in the context of antigen presentation?

<p>To generate 8-10 amino acid long peptides from intracellular viral pathogens that can be loaded onto MHCI molecules. (A)</p> Signup and view all the answers

What is the primary function of MHC I molecules?

<p>To present endogenous antigens to CD8+ T cells (B)</p> Signup and view all the answers

What is the role of co-stimulatory signals in T cell activation?

<p>They are required in addition to the antigen-specific signal for full T cell activation (A)</p> Signup and view all the answers

Which cells are considered professional antigen-presenting cells (APCs)?

<p>Dendritic cells, macrophages, and B cells (A)</p> Signup and view all the answers

What is the primary function of MHC II molecules?

<p>To present exogenous antigens to CD4+ T cells (A)</p> Signup and view all the answers

Which cytokine is primarily responsible for promoting T cell proliferation and differentiation?

<p>Interleukin-2 (IL-2) (B)</p> Signup and view all the answers

What is the role of tetanus toxin in the pathogenesis of tetanus?

<p>It inhibits neurotransmitter release, causing muscle spasms (A)</p> Signup and view all the answers

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