WK 5 - Basic Immunology

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What is the primary function of CD8+ cytotoxic T cells in the immune system?

To produce antibodies against pathogens

To stimulate the activity of B cells

To directly kill virally infected cells (correct)

To engulf foreign particles and bacteria

Which of the following is NOT a peripheral lymphoid organ?

Bone marrow (correct)

Lymph nodes

Spleen

Lymph vessels

What is the primary function of the thymus in the immune system?

Production of antibodies

Maturation of T cells (correct)

Maturation of B cells

Antigen presentation

What is the main difference between the innate and adaptive immune responses?

Innate response is non-specific, while adaptive response is specific Signup and view all the answers

What is the function of lymph vessels in the immune system?

To bring lymphatic fluid from tissues to lymph nodes Signup and view all the answers

What is the role of the spleen in the immune system?

Antigen presentation and non-immune functions Signup and view all the answers

What is the estimated number of epitopes recognised by the immune system?

Millions Signup and view all the answers

Which of the following is NOT a key anatomic component of the immune system?

Muscles Signup and view all the answers

What is the role of antigen presenting cells?

To present antigens to T-cells Signup and view all the answers

What is the origin of all blood cells?

Bone marrow Signup and view all the answers

What is the role of natural killer cells?

Part of the innate immune response Signup and view all the answers

What is the name of the layer of white blood cells that forms when blood is spun down in a lab?

Buffy coat Signup and view all the answers

What is the primary function of the innate immune system?

To provide a general defense against infection Signup and view all the answers

What is the characteristic of the adaptive immune response?

It takes several days to a week to become effective Signup and view all the answers

What is the role of the innate immune system in triggering the adaptive immune response?

It triggers the adaptive immune response Signup and view all the answers

What is the main function of neutrophils in the immune system?

To efficiently phagocytose and destroy a range of microbes Signup and view all the answers

What is the characteristic of the innate immune response in terms of specificity?

It is non-specific and reacts to common patterns on microbe surfaces Signup and view all the answers

What is the difference between MALT, BALT, and GALT?

They are all types of peripheral lymphoid organs Signup and view all the answers

What is the primary role of eosinophils and basophils?

To defend against parasites Signup and view all the answers

What is the relationship between the innate and adaptive immune responses?

The innate immune response triggers the adaptive immune response Signup and view all the answers

What is the main function of mast cells?

To promote allergic inflammation Signup and view all the answers

What is unique about natural killer cells?

They do not display antigen recognition receptors Signup and view all the answers

What would happen in the absence of neutrophils?

Rapid, overwhelming bacterial infection would occur Signup and view all the answers

Where do mast cells reside?

In tissue Signup and view all the answers

What is the primary role of macrophages in the innate immune system?

Phagocytosing microbes and releasing cytokines and chemokines Signup and view all the answers

What is the primary function of dendritic cells in the immune system?

Presenting antigens to lymphocytes and activating adaptive immunity Signup and view all the answers

What is the key role of natural killer cells in the immune system?

Killing invading pathogens directly Signup and view all the answers

What is the difference between monocytes and macrophages?

Macrophages are resident in tissues, while monocytes circulate in the blood Signup and view all the answers

What is the mechanism by which dendritic cells ingest free proteins in the blood?

Macropinocytosis Signup and view all the answers

What is the role of dendritic cells in bridging the innate and adaptive immune systems?