30 Questions
What is the primary function of CD8+ cytotoxic T cells in the immune system?
To directly kill virally infected cells
Which of the following is NOT a peripheral lymphoid organ?
Bone marrow
What is the primary function of the thymus in the immune system?
Maturation of T cells
What is the main difference between the innate and adaptive immune responses?
Innate response is non-specific, while adaptive response is specific
What is the function of lymph vessels in the immune system?
To bring lymphatic fluid from tissues to lymph nodes
What is the role of the spleen in the immune system?
Antigen presentation and non-immune functions
What is the estimated number of epitopes recognised by the immune system?
Millions
Which of the following is NOT a key anatomic component of the immune system?
Muscles
What is the role of antigen presenting cells?
To present antigens to T-cells
What is the origin of all blood cells?
Bone marrow
What is the role of natural killer cells?
Part of the innate immune response
What is the name of the layer of white blood cells that forms when blood is spun down in a lab?
Buffy coat
What is the primary function of the innate immune system?
To provide a general defense against infection
What is the characteristic of the adaptive immune response?
It takes several days to a week to become effective
What is the role of the innate immune system in triggering the adaptive immune response?
It triggers the adaptive immune response
What is the main function of neutrophils in the immune system?
To efficiently phagocytose and destroy a range of microbes
What is the characteristic of the innate immune response in terms of specificity?
It is non-specific and reacts to common patterns on microbe surfaces
What is the difference between MALT, BALT, and GALT?
They are all types of peripheral lymphoid organs
What is the primary role of eosinophils and basophils?
To defend against parasites
What is the relationship between the innate and adaptive immune responses?
The innate immune response triggers the adaptive immune response
What is the main function of mast cells?
To promote allergic inflammation
What is unique about natural killer cells?
They do not display antigen recognition receptors
What would happen in the absence of neutrophils?
Rapid, overwhelming bacterial infection would occur
Where do mast cells reside?
In tissue
What is the primary role of macrophages in the innate immune system?
Phagocytosing microbes and releasing cytokines and chemokines
What is the primary function of dendritic cells in the immune system?
Presenting antigens to lymphocytes and activating adaptive immunity
What is the key role of natural killer cells in the immune system?
Killing invading pathogens directly
What is the difference between monocytes and macrophages?
Macrophages are resident in tissues, while monocytes circulate in the blood
What is the mechanism by which dendritic cells ingest free proteins in the blood?
Macropinocytosis
What is the role of dendritic cells in bridging the innate and adaptive immune systems?
Presenting antigens to lymphocytes and activating adaptive immunity
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