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Immunology of Gut Mucosa

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Questions and Answers

What is the primary function of mucins in the gut?

To facilitate the colonization of beneficial commensal gut bacteria

To modulate the immune response to allergens

To regulate the uptake of nutrients from the gut

To trap and remove pathogens and intestinal antigens from the GI tract (correct)

What is the approximate concentration of bacteria in the colon?

10^3/ml

10^9/ml

10^12/ml (correct)

10^6/ml

What is the function of beneficial commensal gut bacteria?

To produce vitamins and break down toxins

To communicate with the nervous system

To prevent colonization by pathogens

All of the above (correct)

What is the purpose of Waldeyer’s Ring?

To guard the entrance to the respiratory and GI tracts Signup and view all the answers

What is the characteristic of mucins that allows them to trap pathogens?

Their extended, well-hydrated configuration Signup and view all the answers

What is the function of Peyer’s patches in the gut?

To function as mini-lymph nodes, identifying and responding to pathogens Signup and view all the answers

What is the composition of isolated lymphoid follicles in the gut?

Primarily composed of B cells Signup and view all the answers

What is the result of pathogens becoming entangled in mucins?

They are removed from the body through the GI tract Signup and view all the answers

What is the purpose of the appendix in the gut?

To function as a lymphoid organ, packed with lymphoid follicles Signup and view all the answers

What is the mechanism by which mucins are formed in the gut?

Through the formation of di-sulfide bonds between glycoproteins Signup and view all the answers