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What type of chromosomal rearrangement produces a hybrid gene encoding a fusion protein with constitutive activity?
What type of chromosomal rearrangement produces a hybrid gene encoding a fusion protein with constitutive activity?
Which mechanism involves the inappropriate overproduction of a growth-regulatory gene due to changes in its promoter?
Which mechanism involves the inappropriate overproduction of a growth-regulatory gene due to changes in its promoter?
What is the main function of the Ras protein in regulating cell growth and differentiation?
What is the main function of the Ras protein in regulating cell growth and differentiation?
Which genetic alteration in the Ras gene reduces its GTPase activity and affects its ability to break up GTP molecules?
Which genetic alteration in the Ras gene reduces its GTPase activity and affects its ability to break up GTP molecules?
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In CML, which genetic abnormality leads to the formation of the Philadelphia chromosome?
In CML, which genetic abnormality leads to the formation of the Philadelphia chromosome?
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What is Imatinib mesylate commonly used for in the treatment of CML?
What is Imatinib mesylate commonly used for in the treatment of CML?
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Which of the following leads to the production of oncoproteins that are different from their normal counterparts?
Which of the following leads to the production of oncoproteins that are different from their normal counterparts?
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'Alterations in the ras gene reduce its GTPase activity' is an example of what type of genetic change?
'Alterations in the ras gene reduce its GTPase activity' is an example of what type of genetic change?
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