Immunization Quiz
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Questions and Answers

What is the main difference between passive and active immunization?

  • Passive immunization involves administration of live virulent vaccines, while active immunization provides long-lasting immunity through transfer of antibodies.
  • Passive immunization involves administration of an antigen to develop an immune response, while active immunization provides temporary immunity through transfer of antibodies.
  • Passive immunization provides long-lasting immunity through transfer of antibodies, while active immunization involves administration of live virulent vaccines.
  • Passive immunization provides temporary immunity through transfer of antibodies, while active immunization involves administration of an antigen to develop an immune response. (correct)

What are the requirements of an ideal vaccine?

  • Inexpensive, inconsistent in formulation, unstable, short shelf-life, able to induce inappropriate immune response, incorporate a single epitope, induce short-lived immune response, induce no memory, and have adverse effects.
  • Inexpensive, consistent in formulation, unstable, short shelf-life, able to induce inappropriate immune response, incorporate a range of epitopes, induce short-lived immune response, induce no memory, and have adverse effects.
  • Inexpensive, consistent in formulation, stable, long shelf-life, able to induce appropriate immune response, incorporate a range of epitopes, induce long-lived immune response, induce memory, and have no adverse effects. (correct)
  • Expensive, consistent in formulation, stable, short shelf-life, able to induce inappropriate immune response, incorporate a single epitope, induce short-lived immune response, induce no memory, and have adverse effects.

What is the main difference between infectious and non-infectious vaccines?

  • Infectious vaccines infect an animal without producing disease, while non-infectious vaccines are less efficacious and require up to 3 doses. (correct)
  • Infectious vaccines infect an animal without producing disease, while non-infectious vaccines are single-dose effective.
  • Infectious vaccines are less efficacious and require up to 3 doses, while non-infectious vaccines infect an animal without producing disease.
  • Infectious vaccines require up to 3 doses, while non-infectious vaccines infect an animal without producing disease.

What are possible side-effects of vaccines?

<p>Pain, redness, or swelling at the injection site; mild fever; and allergic reactions. (C)</p> Signup and view all the answers

Which type of vaccine involves intact and viable organism but with reduced virulence?

<p>Live attenuated vaccine (B)</p> Signup and view all the answers

What is the means of attenuation in live attenuated vaccines?

<p>All of the above (D)</p> Signup and view all the answers

Which vaccine type requires adjuvants and has a higher risk of causing disease?

<p>Killed whole organism vaccine (C)</p> Signup and view all the answers

What is a characteristic of subunit vaccines?

<p>Contain only the immunogenic structural protein (A)</p> Signup and view all the answers

What is the method of production for naked DNA vaccines?

<p>Gene inserted into a bacterial plasmid (A)</p> Signup and view all the answers

What are the hallmarks of an ideal adjuvant?

<p>All of the above (D)</p> Signup and view all the answers

Which type of adjuvant involves aluminium salts mixed with the antigen to form a granuloma for prolonged antigenic stimulation?

<p>Depot adjuvants (B)</p> Signup and view all the answers

What is a potential adverse consequence of vaccines?

<p>All of the above (D)</p> Signup and view all the answers

What are potential factors leading to a dog developing the disease for which it was vaccinated?

<p>All of the above (D)</p> Signup and view all the answers

Which type of vaccine may induce chronic inflammation linked to the carcinogenesis of feline injection site sarcoma?

<p>Killed whole organism vaccine (C)</p> Signup and view all the answers

What vaccine factor could result in the animal developing the disease it was vaccinated against?

<p>All of the above (D)</p> Signup and view all the answers

What host factor could result in the animal developing the disease it was vaccinated against?

<p>All of the above (D)</p> Signup and view all the answers

What is the main difference between passive and active immunization?

<p>Passive immunization involves transfer of antibodies for temporary immunity, while active immunization involves administration of an antigen to develop long-lasting immune response. (A)</p> Signup and view all the answers

What are the requirements of an ideal vaccine?

<p>Inexpensive, consistent in formulation, stable, long shelf-life, able to induce appropriate immune response, no adverse effects. (D)</p> Signup and view all the answers

What is the main difference between infectious and non-infectious vaccines?

<p>Infectious vaccines involve infecting an animal without producing disease, while non-infectious vaccines involve killed whole, subunit, or naked DNA. (A)</p> Signup and view all the answers

What are some possible vaccine side-effects?

<p>Chronic inflammation, adverse immune response, allergic reactions, mild fever. (C)</p> Signup and view all the answers

What is the main disadvantage of live attenuated vaccines?

<p>Reversion of virulence (C)</p> Signup and view all the answers

What is the main disadvantage of killed whole organism vaccines?

<p>More risk of containing contaminating organisms (A)</p> Signup and view all the answers

Which type of vaccine requires adjuvants and has a higher risk of causing disease?

<p>Killed whole organism vaccines (A)</p> Signup and view all the answers

What is the means of attenuation in live attenuated vaccines?

<p>Multiple Passaging (C)</p> Signup and view all the answers

What is a characteristic of subunit vaccines?

<p>Lower doses required (B)</p> Signup and view all the answers

What is the method of production for naked DNA vaccines?

<p>Gene inserted into a bacterial plasmid (C)</p> Signup and view all the answers

What is the main disadvantage of recombinant organism vaccines?

<p>Reversion of virulence (C)</p> Signup and view all the answers

What is the main advantage of killed whole organism vaccines?

<p>Fewer doses required (B)</p> Signup and view all the answers

Which adjuvant involves aluminium salts mixed with the antigen to form a granuloma for prolonged antigenic stimulation?

<p>Depot adjuvants (B)</p> Signup and view all the answers

What is a potential adverse consequence of vaccines related to feline injection site sarcoma?

<p>Increased risk with multiple injections (A)</p> Signup and view all the answers

What host factor could result in the animal developing the disease it was vaccinated against?

<p>Maternal antibody interference (B)</p> Signup and view all the answers

What vaccine factor could result in the animal developing the disease it was vaccinated against?

<p>Reversal to virulence (B)</p> Signup and view all the answers

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