Immunization Quiz
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Questions and Answers

What is the main difference between passive and active immunization?

  • Passive immunization involves administration of live virulent vaccines, while active immunization provides long-lasting immunity through transfer of antibodies.
  • Passive immunization involves administration of an antigen to develop an immune response, while active immunization provides temporary immunity through transfer of antibodies.
  • Passive immunization provides long-lasting immunity through transfer of antibodies, while active immunization involves administration of live virulent vaccines.
  • Passive immunization provides temporary immunity through transfer of antibodies, while active immunization involves administration of an antigen to develop an immune response. (correct)
  • What are the requirements of an ideal vaccine?

  • Inexpensive, inconsistent in formulation, unstable, short shelf-life, able to induce inappropriate immune response, incorporate a single epitope, induce short-lived immune response, induce no memory, and have adverse effects.
  • Inexpensive, consistent in formulation, unstable, short shelf-life, able to induce inappropriate immune response, incorporate a range of epitopes, induce short-lived immune response, induce no memory, and have adverse effects.
  • Inexpensive, consistent in formulation, stable, long shelf-life, able to induce appropriate immune response, incorporate a range of epitopes, induce long-lived immune response, induce memory, and have no adverse effects. (correct)
  • Expensive, consistent in formulation, stable, short shelf-life, able to induce inappropriate immune response, incorporate a single epitope, induce short-lived immune response, induce no memory, and have adverse effects.
  • What is the main difference between infectious and non-infectious vaccines?

  • Infectious vaccines infect an animal without producing disease, while non-infectious vaccines are less efficacious and require up to 3 doses. (correct)
  • Infectious vaccines infect an animal without producing disease, while non-infectious vaccines are single-dose effective.
  • Infectious vaccines are less efficacious and require up to 3 doses, while non-infectious vaccines infect an animal without producing disease.
  • Infectious vaccines require up to 3 doses, while non-infectious vaccines infect an animal without producing disease.
  • What are possible side-effects of vaccines?

    <p>Pain, redness, or swelling at the injection site; mild fever; and allergic reactions.</p> Signup and view all the answers

    Which type of vaccine involves intact and viable organism but with reduced virulence?

    <p>Live attenuated vaccine</p> Signup and view all the answers

    What is the means of attenuation in live attenuated vaccines?

    <p>All of the above</p> Signup and view all the answers

    Which vaccine type requires adjuvants and has a higher risk of causing disease?

    <p>Killed whole organism vaccine</p> Signup and view all the answers

    What is a characteristic of subunit vaccines?

    <p>Contain only the immunogenic structural protein</p> Signup and view all the answers

    What is the method of production for naked DNA vaccines?

    <p>Gene inserted into a bacterial plasmid</p> Signup and view all the answers

    What are the hallmarks of an ideal adjuvant?

    <p>All of the above</p> Signup and view all the answers

    Which type of adjuvant involves aluminium salts mixed with the antigen to form a granuloma for prolonged antigenic stimulation?

    <p>Depot adjuvants</p> Signup and view all the answers

    What is a potential adverse consequence of vaccines?

    <p>All of the above</p> Signup and view all the answers

    What are potential factors leading to a dog developing the disease for which it was vaccinated?

    <p>All of the above</p> Signup and view all the answers

    Which type of vaccine may induce chronic inflammation linked to the carcinogenesis of feline injection site sarcoma?

    <p>Killed whole organism vaccine</p> Signup and view all the answers

    What vaccine factor could result in the animal developing the disease it was vaccinated against?

    <p>All of the above</p> Signup and view all the answers

    What host factor could result in the animal developing the disease it was vaccinated against?

    <p>All of the above</p> Signup and view all the answers

    What is the main difference between passive and active immunization?

    <p>Passive immunization involves transfer of antibodies for temporary immunity, while active immunization involves administration of an antigen to develop long-lasting immune response.</p> Signup and view all the answers

    What are the requirements of an ideal vaccine?

    <p>Inexpensive, consistent in formulation, stable, long shelf-life, able to induce appropriate immune response, no adverse effects.</p> Signup and view all the answers

    What is the main difference between infectious and non-infectious vaccines?

    <p>Infectious vaccines involve infecting an animal without producing disease, while non-infectious vaccines involve killed whole, subunit, or naked DNA.</p> Signup and view all the answers

    What are some possible vaccine side-effects?

    <p>Chronic inflammation, adverse immune response, allergic reactions, mild fever.</p> Signup and view all the answers

    What is the main disadvantage of live attenuated vaccines?

    <p>Reversion of virulence</p> Signup and view all the answers

    What is the main disadvantage of killed whole organism vaccines?

    <p>More risk of containing contaminating organisms</p> Signup and view all the answers

    Which type of vaccine requires adjuvants and has a higher risk of causing disease?

    <p>Killed whole organism vaccines</p> Signup and view all the answers

    What is the means of attenuation in live attenuated vaccines?

    <p>Multiple Passaging</p> Signup and view all the answers

    What is a characteristic of subunit vaccines?

    <p>Lower doses required</p> Signup and view all the answers

    What is the method of production for naked DNA vaccines?

    <p>Gene inserted into a bacterial plasmid</p> Signup and view all the answers

    What is the main disadvantage of recombinant organism vaccines?

    <p>Reversion of virulence</p> Signup and view all the answers

    What is the main advantage of killed whole organism vaccines?

    <p>Fewer doses required</p> Signup and view all the answers

    Which adjuvant involves aluminium salts mixed with the antigen to form a granuloma for prolonged antigenic stimulation?

    <p>Depot adjuvants</p> Signup and view all the answers

    What is a potential adverse consequence of vaccines related to feline injection site sarcoma?

    <p>Increased risk with multiple injections</p> Signup and view all the answers

    What host factor could result in the animal developing the disease it was vaccinated against?

    <p>Maternal antibody interference</p> Signup and view all the answers

    What vaccine factor could result in the animal developing the disease it was vaccinated against?

    <p>Reversal to virulence</p> Signup and view all the answers

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