Immunity and Cell Death Quiz
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Questions and Answers

What is the defining characteristic of apoptosis?

  • Cell fragmentation without cellular regulation
  • Uncontrolled cell swelling
  • Highly regulated process associated with normal development (correct)
  • Inflammation as a result of cell damage
  • Which of the following correctly describes the structure of an antibody?

  • Has equal regions of variable and constant sequences
  • Contains two heavy chains and one light chain
  • Consists of three polypeptide chains
  • Made up of four polypeptide chains including two heavy chains and two light chains (correct)
  • What initiates inflammation in necrosis?

  • Activation of the complement system
  • The presence of memory T lymphocytes
  • Release of intracellular contents from damaged cells (correct)
  • Cell shrinkage and fragmentation
  • What is the primary function of humoral immunity?

    <p>Production and usage of antibodies (B)</p> Signup and view all the answers

    Which type of necrosis is characterized by softening of tissues and formation of pus?

    <p>Liquefactive necrosis (C)</p> Signup and view all the answers

    Which regions of an antibody are responsible for its specificity?

    <p>Variable regions (B)</p> Signup and view all the answers

    In which of the following is necrosis NOT involved?

    <p>Retraction of blood vessels (C)</p> Signup and view all the answers

    What role do memory B cells play in the immune system?

    <p>They provide long-lasting immunity upon re-exposure to the same antigen. (C)</p> Signup and view all the answers

    Flashcards

    Immunity

    The body's ability to defend against infection and disease, involving a complex system of cells, tissues, and organs.

    Innate Immunity

    The first line of defense, characterized by rapid, non-specific responses against pathogens.

    Adaptive Immunity

    A type of adaptive immunity, characterized by specificity and memory, developing over time.

    Apoptosis

    A highly regulated process of cell death, essential for development and removing unwanted cells.

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    Necrosis

    Cell death caused by injuries or trauma, often involving inflammation.

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    Antibodies

    Proteins produced by B lymphocytes that recognize and bind to specific antigens.

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    Humoral Immunity

    A branch of adaptive immunity focused on antibody production and use.

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    Plasma Cells

    Mature B lymphocytes that secrete antibodies to neutralize toxins or target pathogens.

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    Study Notes

    Immunity

    • Immunity is the body's ability to resist infection and disease.
    • It involves a complex system of cells, tissues, and organs working together to defend against pathogens.
    • Two main branches of immunity: innate and adaptive.
    • Innate immunity is the first line of defense, providing rapid, non-specific responses.
    • Adaptive immunity, characterized by specificity and memory, develops over time.

    Cell Death

    • Apoptosis (programmed cell death): A highly regulated process essential for development and tissue homeostasis.

    • Characterized by distinct morphological changes, including nuclear fragmentation and cell shrinkage.

    • Critical for removal of damaged or unwanted cells.

    • Often triggered by cellular stress or DNA damage.

    • Plays a role in immune responses and development.

    • Necrosis: A form of cell death caused by injury or trauma, often involving inflammation.

    • It results in uncontrolled cell swelling and disruption of cellular contents.

    Antibody Structure

    • Antibodies (immunoglobulins): Proteins produced by B lymphocytes that recognize and bind to specific antigens.
    • Basic antibody structure consists of four polypeptide chains. Two heavy chains and two light chains.
    • Regions of variable amino acid sequences (variable regions) form antigen-binding sites.
    • Constant regions (constant regions) determine antibody effector function.
    • Antibody classes (e.g., IgG, IgM, IgA, IgE, IgD) have distinct roles in the immune response.

    Necrosis

    • Necrosis is a form of cell death that occurs due to injuries or damages.
    • A prominent feature of necrosis is inflammation, initiated when damaged cells release intracellular contents.
    • Necrosis is not a regulated process and is often associated with tissue damage and inflammation.
    • Different types of necrosis include coagulative, liquefactive, and gangrenous necrosis, each with distinct characteristics.
    • Necrosis involves degradation of the cell membrane, and leakage of intracellular contents.

    Humoral Immunity

    • Humoral immunity is a branch of adaptive immunity.
    • Its primary function is the production and use of antibodies.
    • B lymphocytes mature into plasma cells that secrete antibodies.
    • Antibodies bind to specific antigens, neutralizing toxins or facilitating their destruction.
    • Antibodies also activate the complement system.
    • This process helps clear pathogens and cellular debris from the body.
    • Memory B cells are crucial in providing long-lasting immunity upon re-exposure to the same antigen.

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    Description

    Test your knowledge on the body's immune system and the processes of cell death. This quiz covers innate and adaptive immunity as well as apoptosis and necrosis. Explore key concepts and terminologies related to these critical biological processes.

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