34 Questions
Which organ is responsible for T-lymphocyte proliferation and differentiation?
Thymus
What are the primary lymphoid organs?
Bone marrow and thymus
What are the functions of lymph nodes?
All of the above
Which organs are considered primary lymphoid organs?
Lymph nodes
What is the main function of lymph nodes?
Filtration by macrophages
Where are T-cells produced?
Bone marrow
What is the function of the thymus?
T-cell maturation
Which cells are involved in humoral immunity?
B-cells
Which cells are involved in cell-mediated immunity?
T-cells
Which cells are considered antigen-presenting cells (APCs)?
Dendritic cells
What is required for T-cell receptor (TCR) recognition of antigens?
Antigen presentation by MHC molecules
Which of the following is the main purpose of the Blood-Thymus Barrier?
To prevent immature T cells from contacting foreign antigens
What happens to immature T cells if they come into contact with foreign antigens during development in the thymus?
They undergo apoptosis
Why is it important for immature T cells to be protected from random antigens during development in the thymus?
Contact with random antigens can cause the death of T cells
Which organ is responsible for filtering blood and removing damaged blood cells and pathogens?
Spleen
Which organ is involved in T cell maturation and has a cortex rich in developing thymocytes and a medulla containing mature T cells?
Thymus
Which organ is responsible for monitoring intestinal antigens and is located in the small intestine?
Peyer's Patches
Which organ is responsible for guarding against inhaled and ingested pathogens and is located in the throat region?
Tonsils
Which anatomical structure in the thymus contains mature T cells and specialized thymic epithelial cells called medullary epithelial cells?
Medulla
Which cells form a network in the thymus that supports developing thymocytes and helps create a microenvironment for T cell maturation and selection?
Epithelial Reticular Cells
Which type of cells are produced in the bone marrow, including immune cells like B cells and some T cell precursors?
B Cells
Which anatomical structure in the thymus is involved in regulatory processes and is composed of concentrically arranged epithelial cells?
Hassall's Corpuscles
Which organ is responsible for filtering lymph and facilitating immune cell interactions, and is found along lymphatic vessels?
Lymph Nodes
Which anatomical structure in the thymus contains densely packed developing thymocytes and supports T cell maturation and selection?
Cortex
Which cells are found in the red pulp of the spleen?
Macrophages, lymphocytes, and reticular cells
What is the main function of Peyer's patches?
To monitor and respond to antigens entering the gut
Which cells are responsible for antibody production and humoral immune responses?
B cells
Which area of the lymph node is involved in immune responses and contains high endothelial venules (HEVs)?
Paracortex
What is the function of the Blood-Thymus Barrier?
To prevent direct contact between circulating antigens and developing T cells
Which cells are involved in cellular immune responses and directly attack infected cells?
T cells
Where are lymphatic nodules found?
Scattered in various mucous membranes and lymphoid tissues
What is the main function of the white pulp in the spleen?
To monitor blood for antigens and initiate immune responses
Which cells capture, process, and present antigens to initiate immune responses?
Dendritic cells
What are the main components of the Blood-Thymus Barrier?
Epithelial reticular cells and capillary endothelial cells
Test your knowledge on the functions and organs of the immune system. Learn about the immune system's role in protecting the body from invaders and its ability to distinguish "self." Explore primary lymphoid organs like the bone marrow and thymus, as well as secondary lymphoid organs such as lymph nodes, spleen, and MALT. Challenge yourself with this quiz!
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