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Immune Response Mechanisms

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Questions and Answers

Where does proteolytic cleavage usually occur in the process of antibody production?

Rough endoplasmic reticulum (correct)
Plasma membrane
Golgi apparatus
Lysosome

What determines the class type of an antibody?

Location of disulfide bonds and hinge region (correct)
Type of immunological response
Length of the V region
Type of antigen recognized

What is the function of CDRs in immunoglobulins?

To recognize and bind to antigens (correct)
To interact with Fc receptors
To provide structural support to the antibody
To activate complement proteins

How are monoclonal antibodies produced in the laboratory?

By fusing single antibody-producing cells with myeloma cells (B) Signup and view all the answers

What is the purpose of somatic hypermutation in antibody production?

To enhance the binding affinity of antibodies to antigens (A) Signup and view all the answers

What is the result of V(D)J recombination in antibody production?

The generation of a diverse repertoire of antibody genes (C) Signup and view all the answers

What is the role of junctional diversity in antibody production?

To introduce random nucleotides at the junctions of V, D, and J segments (B) Signup and view all the answers

What is the main difference between IgM and IgG antibodies?

IgM is produced early in the immune response, while IgG is produced later (B) Signup and view all the answers

What is the purpose of affinity maturation in antibody production?

To enhance the binding affinity of antibodies to antigens (B) Signup and view all the answers

What is the result of somatic recombination in antibody production?

The generation of a diverse repertoire of antibody genes (A) Signup and view all the answers