Podcast
Questions and Answers
What is a strong association of vitiligo?
What is a strong association of vitiligo?
- Autoimmune thyroid disorders (correct)
- Excessive UV exposure
- Hypopigmentation
- Diabetes
Which of the following is NOT a high-risk factor for melanoma?
Which of the following is NOT a high-risk factor for melanoma?
- Caucasian descent (correct)
- Familial dysplastic nevi
- Whites (fair skin)
- Red hair
What is the main clinical feature of melanoma?
What is the main clinical feature of melanoma?
- Jaundice
- Erythema
- Hypopigmentation (correct)
- Hyperpigmentation
Which pathway is associated with pro-growth signaling in melanoma?
Which pathway is associated with pro-growth signaling in melanoma?
What are typical markers for melanoma?
What are typical markers for melanoma?
Which pattern describes radial growth in metastatic melanoma?
Which pattern describes radial growth in metastatic melanoma?
What type of nevi is associated with a high risk of developing melanoma?
What type of nevi is associated with a high risk of developing melanoma?
Which of the following is NOT a feature of atypical melanocytes in invasive melanoma?
Which of the following is NOT a feature of atypical melanocytes in invasive melanoma?
'Vertical Growth Phase' in melanoma represents:
'Vertical Growth Phase' in melanoma represents:
Which protein controls cell signaling pathways responsible for growth, migration, adhesion, cytoskeletal integrity, survival, and differentiation?
Which protein controls cell signaling pathways responsible for growth, migration, adhesion, cytoskeletal integrity, survival, and differentiation?
In melanoma, RAS mutation occurs by switching signaling from BRAF to which other protein?
In melanoma, RAS mutation occurs by switching signaling from BRAF to which other protein?
Which syndrome is associated with germline mutations in BRAF?
Which syndrome is associated with germline mutations in BRAF?
What is the function of TERT (Telomerase reverse transcriptase) in rapidly dividing cells?
What is the function of TERT (Telomerase reverse transcriptase) in rapidly dividing cells?
Which clinical feature is NOT commonly associated with Hutchinson's sign?
Which clinical feature is NOT commonly associated with Hutchinson's sign?
Which type of carcinoma is NOT mentioned as being associated with mutations in TERT promoters?
Which type of carcinoma is NOT mentioned as being associated with mutations in TERT promoters?
What cellular processes are affected by BRAF mutations?
What cellular processes are affected by BRAF mutations?
'SLIDES' in the text refers to what cellular component?
'SLIDES' in the text refers to what cellular component?
'Hutchinson's sign' is characterized by which specific feature on the nails?
'Hutchinson's sign' is characterized by which specific feature on the nails?
Which characteristic is typical of Amelanotic melanoma?
Which characteristic is typical of Amelanotic melanoma?
Which feature distinguishes Melanoma in Situ from Invasive Melanoma?
Which feature distinguishes Melanoma in Situ from Invasive Melanoma?
What is a key characteristic of Nodular Melanomas?
What is a key characteristic of Nodular Melanomas?
What distinguishes Superficial Spreading Melanomas histologically?
What distinguishes Superficial Spreading Melanomas histologically?
Which subtype of Melanoma is known to affect the skin of soles and palms?
Which subtype of Melanoma is known to affect the skin of soles and palms?
What histological feature is common in Acral Lentiginous Melanomas?
What histological feature is common in Acral Lentiginous Melanomas?
Which subtype of melanoma is characterized by a reddish slightly elevated plaque?
Which subtype of melanoma is characterized by a reddish slightly elevated plaque?
'Hutchinson’s sign' is associated with which type of Melanoma?
'Hutchinson’s sign' is associated with which type of Melanoma?
Which characteristic is typical of Lentigo Maligna Melanoma?
Which characteristic is typical of Lentigo Maligna Melanoma?
In typical melanocytes in the basal layer, which feature is NOT commonly observed?
In typical melanocytes in the basal layer, which feature is NOT commonly observed?
Which type of melanoma cells are noted for their presence in nests or single cells at the basal layer?
Which type of melanoma cells are noted for their presence in nests or single cells at the basal layer?
Which characteristic is NOT associated with Invasive Melanomas?
Which characteristic is NOT associated with Invasive Melanomas?
What is a common marker that is NEGATIVE in Paget's disease but POSITIVE in both benign nevus and melanoma?
What is a common marker that is NEGATIVE in Paget's disease but POSITIVE in both benign nevus and melanoma?
Which level of Clark's system of invasion involves no penetration of the basement membrane?
Which level of Clark's system of invasion involves no penetration of the basement membrane?
Which feature is characteristic of Nodular Melanoma?
Which feature is characteristic of Nodular Melanoma?
What differentiates Lentigo Maligna from Lentigo Maligna Invasive?
What differentiates Lentigo Maligna from Lentigo Maligna Invasive?
'Spindled or epithelioid' cells are most commonly seen in which invasive type of melanoma?
'Spindled or epithelioid' cells are most commonly seen in which invasive type of melanoma?
'Multinucleated melanoma cells' are typically found in which type of melanoma?
'Multinucleated melanoma cells' are typically found in which type of melanoma?
'Solar elastosis' is a feature most commonly associated with which type of melanoma?
'Solar elastosis' is a feature most commonly associated with which type of melanoma?
