IBS Quiz: Colitis, Symptoms, and Therapy
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Questions and Answers

What is a more characteristic feature of ulcerative colitis compared to Crohn's disease?

  • Confinement of disease to the small intestine
  • Involvement of the terminal ileum
  • Fistula formation
  • Superficial continuous inflammation of the intestinal mucosa (correct)

Which enzyme's activity should be evaluated before starting therapy in patients receiving azathioprine?

  • HLA DRP
  • Xanthine oxidase
  • TPMT (correct)
  • CYP2D6

In ulcerative colitis, where is the disease mainly located?

  • In the rectum and sigmoid colon
  • In the terminal ileum
  • Throughout the majority of the colon (correct)
  • Only in the rectal area

Which adverse effect is more likely with the combination of infliximab and azathioprine?

<p>Lymphoma (D)</p> Signup and view all the answers

Which drug should be administered intravenously?

<p>Golimumab (C)</p> Signup and view all the answers

What is a potential adverse effect of ustekinumab?

<p>Neural tube defects (B)</p> Signup and view all the answers

What is considered first-line for the prevention of motion sickness?

<p>Scopolamine (B)</p> Signup and view all the answers

Why is the use of promethazine contraindicated in patients less than 2 years old?

<p>May result in fatal respiratory depression (A)</p> Signup and view all the answers

What is a recommended dietary modification for managing nausea and vomiting?

<p>Eating smaller, more frequent meals (C)</p> Signup and view all the answers

Which medication is beneficial in reducing nausea but not vomiting?

<p>Pyridoxine (D)</p> Signup and view all the answers

What must be considered when persistent nausea and/or vomiting requires drug therapy?

<p>Potential teratogenicity of the medication (C)</p> Signup and view all the answers

Why is the transdermal system (patch) preferred for scopolamine administration?

<p>Enhanced patient satisfaction and decreased side effects (A)</p> Signup and view all the answers

In patients with opioid-induced constipation, which medication can be administered in the hospital for short-term use?

<p>Methylnaltrexone (B)</p> Signup and view all the answers

What amount of fiber in the daily diet is recommended to prevent constipation?

<p>50 to 55 g (C)</p> Signup and view all the answers

What is a recommended treatment measure in constipation-predominant IBS for mild symptoms?

<p>Polyethylene glycol (B)</p> Signup and view all the answers

What treatment is recommended in diarrhea-predominant IBS for moderate symptoms along with avoidance of certain foods?

<p>Rifaximin (C)</p> Signup and view all the answers

Which medication may be used for its analgesic effects in patients with IBS-associated pain?

<p>Amitriptyline (C)</p> Signup and view all the answers

What is a common cause of acute diarrhea in the United States according to the text?

<p>Bacterial organisms (C)</p> Signup and view all the answers

What is the recommended therapy for treatment of acute thromboembolism during pregnancy according to ACOG?

<p>Enoxaparin (B)</p> Signup and view all the answers

Why should fondaparinux be avoided for the treatment of acute thromboembolism during pregnancy?

<p>Potential teratogenicity (D)</p> Signup and view all the answers

What is the preferred therapy to prevent heartburn/GERD symptoms during pregnancy according to the information provided?

<p>H2 receptor antagonists (B)</p> Signup and view all the answers

Why is valproic acid and phenobarbital usage suggested to be avoided before conception?

<p>Known teratogenic risks (B)</p> Signup and view all the answers

When does ACOG recommend starting low-dose aspirin in pregnant patients at risk for preeclampsia?

<p>12-16 weeks (D)</p> Signup and view all the answers

Why are direct oral anticoagulants not recommended for use in pregnancy?

<p>Unknown teratogenic potential (D)</p> Signup and view all the answers

Which hormonal agent is supported as the most cost-effective option for managing heavy menstrual bleeding?

<p>Levonorgestrel-releasing intrauterine system (LNG-IUS) (D)</p> Signup and view all the answers

Which nonpharmacologic option has NOT been shown effective in managing dysmenorrhea?

<p>Topical ice packs (B)</p> Signup and view all the answers

What percentage is noted as the extreme prevalence of dysmenorrhea, significantly impacting many individuals' quality of life?

<p>90% (D)</p> Signup and view all the answers

What are considered the first-line treatments for Premenstrual Dysphoric Disorder (PMDD)?

<p>Antidepressants (B)</p> Signup and view all the answers

Which dosing regimen shows LESS negative impact on libido from a medication adverse effect standpoint in managing Premenstrual Syndrome and Premenstrual Dysphoric Disorder?

<p>Luteal phase dosing (D)</p> Signup and view all the answers

Which two medications have been noted to cause birth defects more frequently compared to others when used in Premenstrual Syndrome and Premenstrual Dysphoric Disorder?

<p>Paroxetine and fluoxetine (C)</p> Signup and view all the answers

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