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Questions and Answers
What is believed to have performed both the functions of genetic storage and catalysing chemical reactions in early cells?
What is believed to have performed both the functions of genetic storage and catalysing chemical reactions in early cells?
RNA
What are the roles that DNA and proteins (enzymes) took over from RNA as life evolved?
What are the roles that DNA and proteins (enzymes) took over from RNA as life evolved?
DNA took over genetic storage, while proteins (enzymes) became biological catalysts.
What is an example of RNA's enzymatic properties in modern cells?
What is an example of RNA's enzymatic properties in modern cells?
Ribozymes catalysing the formation of peptide bonds
What is the significance of ribose being formed from methanal, a product of the Miller-Urey experiment?
What is the significance of ribose being formed from methanal, a product of the Miller-Urey experiment?
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What is necessary for the evolution of early cells, as mentioned in the exam tip?
What is necessary for the evolution of early cells, as mentioned in the exam tip?
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What can RNA do spontaneously from nucleotides?
What can RNA do spontaneously from nucleotides?
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What is the process by which deoxyribose in DNA is produced from ribose in RNA?
What is the process by which deoxyribose in DNA is produced from ribose in RNA?
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What can ribozymes join together to form proteins from an RNA template?
What can ribozymes join together to form proteins from an RNA template?
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What is the possible site for the evolution of LUCA?
What is the possible site for the evolution of LUCA?
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What process do organisms near hydrothermal vents use to generate energy?
What process do organisms near hydrothermal vents use to generate energy?
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Where were fossilised structures similar to those produced by modern prokaryotes found?
Where were fossilised structures similar to those produced by modern prokaryotes found?
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What is the approximate age of the fossilised structures found near hydrothermal vents?
What is the approximate age of the fossilised structures found near hydrothermal vents?
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What type of organisms are thought to have produced the fossilised structures found near hydrothermal vents?
What type of organisms are thought to have produced the fossilised structures found near hydrothermal vents?
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What is the significance of the fossilised structures found near hydrothermal vents?
What is the significance of the fossilised structures found near hydrothermal vents?
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What role do membranes play in cells?
What role do membranes play in cells?
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Why is the amphipathic nature of fatty acids significant in membrane formation?
Why is the amphipathic nature of fatty acids significant in membrane formation?
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Describe how lipid molecules behave when placed in water.
Describe how lipid molecules behave when placed in water.
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What might the spontaneous formation of bilayers lead to?
What might the spontaneous formation of bilayers lead to?
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How could triglycerides have evolved during the development of membranes?
How could triglycerides have evolved during the development of membranes?
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What initial composition was likely present in the membranes of the first cells?
What initial composition was likely present in the membranes of the first cells?
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What is the significance of the coalescence of fatty acids in the context of cellular origins?
What is the significance of the coalescence of fatty acids in the context of cellular origins?
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How do the properties of fatty acids contribute to the formation of cellular membranes?
How do the properties of fatty acids contribute to the formation of cellular membranes?
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What role did methane and carbon dioxide play in the early Earth's atmosphere?
What role did methane and carbon dioxide play in the early Earth's atmosphere?
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How did the absence of free oxygen affect the early Earth's atmosphere?
How did the absence of free oxygen affect the early Earth's atmosphere?
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What hypothesis did Alexander Oparin and JBS Haldane propose regarding the origin of life?
What hypothesis did Alexander Oparin and JBS Haldane propose regarding the origin of life?
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Which process may have led to the formation of organic molecules such as amino acids on early Earth?
Which process may have led to the formation of organic molecules such as amino acids on early Earth?
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What was the significance of the higher temperatures on early Earth?
What was the significance of the higher temperatures on early Earth?
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What compounds are thought to have been formed as a result of early Earth conditions?
What compounds are thought to have been formed as a result of early Earth conditions?
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In what way did UV radiation impact the formation of biological molecules on early Earth?
In what way did UV radiation impact the formation of biological molecules on early Earth?
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What is the greenhouse effect in the context of early Earth's atmosphere?
What is the greenhouse effect in the context of early Earth's atmosphere?
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Why is the absence of ozone significant for early Earth conditions?
Why is the absence of ozone significant for early Earth conditions?
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What are the building blocks of early cells thought to be formed during early Earth conditions?
What are the building blocks of early cells thought to be formed during early Earth conditions?
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What was the primary goal of the Miller-Urey experiment?
What was the primary goal of the Miller-Urey experiment?
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Which gases were used in the Miller-Urey experiment to replicate the early atmosphere?
Which gases were used in the Miller-Urey experiment to replicate the early atmosphere?
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How did Miller and Urey simulate lightning in their experiment?
How did Miller and Urey simulate lightning in their experiment?
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What type of molecules did Miller and Urey find in their condensed mixture after the experiment?
What type of molecules did Miller and Urey find in their condensed mixture after the experiment?
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What role did boiling water play in the Miller-Urey experiment?
What role did boiling water play in the Miller-Urey experiment?
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What process did Miller and Urey use to cool their gaseous mixture?
What process did Miller and Urey use to cool their gaseous mixture?
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Why is the Miller-Urey experiment considered significant in the study of the origin of life?
Why is the Miller-Urey experiment considered significant in the study of the origin of life?
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What are the implications of synthesizing simple organic molecules from inorganic ones?
What are the implications of synthesizing simple organic molecules from inorganic ones?
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Study Notes
Origins of Cells
- Conditions on early Earth were instrumental in the origin of biological compounds that made life possible
- Higher atmospheric temperatures due to higher levels of carbon dioxide and methane, leading to the greenhouse effect
- Lack of free oxygen, preventing ozone formation, and allowing UV radiation to penetrate to the surface
- The spontaneous formation of carbon compounds by chemical processes may have occurred due to these conditions
- Adding energy, such as heat or UV radiation, to the mixture of gases in the early atmosphere could have led to the formation of organic molecules
- These organic molecules would have formed the building blocks of early cells, as proposed by Alexander Oparin and JBS Haldane in the 'primordial soup' hypothesis
Formation of Carbon Compounds: Evidence
- The Miller-Urey experiment recreated the conditions thought to have existed on Earth prior to life
- The experiment used a specific apparatus to boil water, mix with gases, add electrical discharges, and cool the mixture
- After a week, the condensed mixture was found to contain traces of simple organic molecules, including amino acids
- The spontaneous formation of vesicles may have occurred due to the amphipathic nature of fatty acids
- Fatty acids are major components of lipids, which can form bilayers with polar parts facing outward and non-polar parts facing inward
- These bilayers can spontaneously form microspheres, or small vesicles, which could have formed the membranes of early cells
The First Cells: RNA
- RNA may have performed both genetic storage and enzymatic functions in early cells, as proposed by the RNA world hypothesis
- RNA can store genetic information and have enzymatic properties
- RNA can assemble spontaneously from nucleotides, replicate itself, and control the rate of chemical reactions
- Evidence for the RNA world hypothesis includes
- Ribose can be formed from methanal, a product of the Miller-Urey experiment
- Deoxyribose in DNA is produced from ribose in an enzyme-catalysed reaction
- Ribozymes are able to join amino acids together to form proteins from an RNA template
Evolution of Life: Hydrothermal Vents
- It is possible that LUCA (Last Universal Common Ancestor) evolved in hydrothermal vents deep in the ocean
- The conditions near hydrothermal vents provide opportunities for organisms to generate energy by chemosynthesis
- Fossilised structures found in sedimentary rocks near deep-sea hydrothermal vents in Quebec, Canada, may be evidence of early life
- The structures are similar to those produced by modern prokaryotes found near hydrothermal vents
- The fossils are at least 3.77 billion years old, but could be more than 4 billion years old
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Description
Revision notes on the origins of cells, covering formation of carbon compounds, evolution of cells, and evidence for evolution of life.