Hypothyroidism and Cretinism Quiz

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Questions and Answers

Which congenital abnormality of the hypothalamo-pituitary thyroid axis causes congenital hypothyroidism with cretinism?

  • Myxedema madness
  • is a correct statement but not the answer to the question. B) is a symptom of hypothyroidism but not a congenital abnormality. C) is a type of goiter but not a congenital abnormality. (correct)
  • Endemic Goiter
  • Graves' disease

What is the clinical finding in endemic goiter?

  • TSH is high, the serum level of T4 and T4 is normal (subclinical hypothyroidism
  • Nervousness, weight loss, hyperphagia, heat intolerance, increase cardiac output, increased pulse pressure, a fine tremor of the outstretched fingers, sweating and variable increment in BMR.
  • Dwarfism and mental retardation with potbellies and enlarged protruded tongues.
  • is a correct statement but not the answer to the question. C) is a symptom of hyperthyroidism but not a clinical finding in endemic goiter. D) is a description of cretinism, not endemic goiter. (correct)

What causes Graves' disease?

  • is a characteristic of endemic goiter, not Graves' disease) C) is a cause of endemic goiter, not Graves' disease) D) is a cause of physiological goiter, not Graves' disease
  • Increase stress and demand for T3 and T4 necessary for growth
  • Autoimmune disease with circulating antibodies formed against TSH receptors (correct)
  • Inadequate thyroid hormone synthesis due to low dietary intake of iodine

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