Hyperthyroidism Pharmacologic Therapy Quiz

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Questions and Answers

Which form of pharmacotherapy is considered the treatment of choice for hyperthyroidism?

  • Thyroid hormone synthesis inhibitors
  • Antithyroid medications
  • Thyroid hormone replacement therapy
  • Administration of the radioisotope 131I (correct)

Why is radioactive iodine therapy contraindicated during pregnancy?

  • It interferes with the synthesis of thyroid hormones
  • It may cause irreversible damage to the thyroid gland
  • It may lead to hypothyroidism in the fetus
  • It crosses the placenta (correct)

What precaution should women of childbearing age take before receiving radioactive iodine therapy?

  • Receive a pregnancy test (correct)
  • Undergo a thyroid function test
  • Undergo a complete blood count test
  • Begin thyroid hormone replacement therapy

For how long should women of childbearing age avoid conceiving following radioactive iodine treatment?

<p>6 months (C)</p> Signup and view all the answers

Why is breast-feeding contraindicated for up to 6 weeks prior to radioactive iodine treatment?

<p>It may expose the infant to radioactive iodine (B)</p> Signup and view all the answers

What percentage of cases does a single dose of radioactive iodine effectively treat?

<p>80% to 90% (D)</p> Signup and view all the answers

What is the primary goal of radioactive iodine therapy (131I)?

<p>To eliminate the hyperthyroid state with a single dose of radiation (D)</p> Signup and view all the answers

Why is radioactive iodine concentrated in the thyroid gland?

<p>Because almost all iodine that enters the body becomes concentrated in the thyroid gland (D)</p> Signup and view all the answers

What is the potential consequence of an ablative dose of radioactive iodine?

<p>Acute release of thyroid hormone and increased symptoms (B)</p> Signup and view all the answers

How is thyroid storm manifested?

<p>Cardiac arrhythmias, fever, and neurologic impairment (A)</p> Signup and view all the answers

What is the purpose of using beta-blockers in radioactive iodine therapy?

<p>To control symptoms of thyroid storm (B)</p> Signup and view all the answers

When is thyroid hormone replacement started after radioactive iodine therapy?

<p>4 to 18 weeks after stopping antithyroid medications (D)</p> Signup and view all the answers

Why can TSH measurements be misleading in the early months following treatment with radioactive iodine?

<p>Due to acute release of thyroid hormone (B)</p> Signup and view all the answers

What is the principal test measured at 3 to 6 weeks following administration of radioactive iodine?

<p>Serum free T4 (C)</p> Signup and view all the answers

When should TSH be measured once a normal thyroid state has been established?

<p>Every 6 to 12 months for life (D)</p> Signup and view all the answers

What is a major advantage of treatment with radioactive iodine compared to antithyroid medications?

<p>Avoids many side effects associated with antithyroid medications (C)</p> Signup and view all the answers

Why might some patients elect to be treated with antithyroid medications rather than radioactive iodine?

<p>Fear of radiation (A)</p> Signup and view all the answers

How can patients receiving radioactive iodine contaminate others?

<p>Through saliva, urine, or radiation emitting from their body (A)</p> Signup and view all the answers

What is the purpose of observing patients for signs of thyroid storm after receiving an ablative dose of radioactive iodine?

<p>To monitor for life-threatening conditions such as cardiac arrhythmias, fever, and neurologic impairment (A)</p> Signup and view all the answers

Why is serum free T4 the principal test measured at 3 to 6 weeks following administration of radioactive iodine?

<p>To differentiate between persistent hyperthyroidism and transient hypothyroidism (A)</p> Signup and view all the answers

What precaution should women of childbearing age take before receiving radioactive iodine therapy?

<p>Use contraception and avoid conceiving for at least 6 months prior to treatment (D)</p> Signup and view all the answers

Why might some patients elect to be treated with antithyroid medications rather than radioactive iodine?

<p>Fear of radiation (B)</p> Signup and view all the answers

When should TSH be measured once a normal thyroid state has been established?

<p>Every 6 to 12 months for life (B)</p> Signup and view all the answers

Why is radioactive iodine therapy contraindicated during pregnancy?

<p>It crosses the placenta (B)</p> Signup and view all the answers

What is the primary goal of radioactive iodine therapy (131I)?

<p>To cause destructive effects on the thyroid gland (C)</p> Signup and view all the answers

Why should women of childbearing age be given a pregnancy test 48 hours before administration of radioactive iodine?

<p>To avoid potential harm to the developing fetus (A)</p> Signup and view all the answers

What is the potential consequence of an ablative dose of radioactive iodine?

<p>Hypothyroidism (D)</p> Signup and view all the answers

Why is breast-feeding contraindicated for up to 6 weeks prior to radioactive iodine treatment?

<p>To prevent radioactive contamination of breast milk (C)</p> Signup and view all the answers

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