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Questions and Answers
What is the primary function of aldosterone in the RAAS cycle?
What is the primary function of aldosterone in the RAAS cycle?
What is the effect of consuming too much sodium on blood pressure?
What is the effect of consuming too much sodium on blood pressure?
How do ACE inhibitors work to lower blood pressure?
How do ACE inhibitors work to lower blood pressure?
What is the relationship between blood volume and blood pressure?
What is the relationship between blood volume and blood pressure?
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Which of the following is a mechanism by which the RAAS cycle increases blood pressure?
Which of the following is a mechanism by which the RAAS cycle increases blood pressure?
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Which of the following is NOT a direct result of LDL protein insudation into endothelial cells?
Which of the following is NOT a direct result of LDL protein insudation into endothelial cells?
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What is the primary consequence of an increased number of LDL proteins in the bloodstream?
What is the primary consequence of an increased number of LDL proteins in the bloodstream?
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What cellular component is primarily responsible for engulfing LDL proteins, leading to the formation of foam cells?
What cellular component is primarily responsible for engulfing LDL proteins, leading to the formation of foam cells?
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What is the role of foam cells in the development of coronary artery disease?
What is the role of foam cells in the development of coronary artery disease?
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What is a thrombus?
What is a thrombus?
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Which of the following is NOT a potential cause of orthostatic hypotension?
Which of the following is NOT a potential cause of orthostatic hypotension?
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What is the key characteristic of hypotension?
What is the key characteristic of hypotension?
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What is the primary issue that leads to right ventricular hypertrophy in pulmonary stenosis?
What is the primary issue that leads to right ventricular hypertrophy in pulmonary stenosis?
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Which of the following is TRUE regarding the relationship between LDL levels and coronary artery disease?
Which of the following is TRUE regarding the relationship between LDL levels and coronary artery disease?
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What is the defining characteristic of orthostatic hypotension?
What is the defining characteristic of orthostatic hypotension?
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Which of the following conditions is NOT associated with secondary hypertension?
Which of the following conditions is NOT associated with secondary hypertension?
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Which subtype of primary hypertension involves only increased diastolic blood pressure?
Which subtype of primary hypertension involves only increased diastolic blood pressure?
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What is the common characteristic of primary hypertension subtypes?
What is the common characteristic of primary hypertension subtypes?
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Which of the following is a modifiable risk factor for primary hypertension?
Which of the following is a modifiable risk factor for primary hypertension?
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Which of the following organs is NOT likely to be affected by end-organ damage resulting from primary hypertension?
Which of the following organs is NOT likely to be affected by end-organ damage resulting from primary hypertension?
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In which population is secondary hypertension more commonly observed?
In which population is secondary hypertension more commonly observed?
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What is a key characteristic that distinguishes primary hypertension from secondary hypertension?
What is a key characteristic that distinguishes primary hypertension from secondary hypertension?
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Which of the following is least likely to be a contributing factor to primary hypertension?
Which of the following is least likely to be a contributing factor to primary hypertension?
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Which of the following types of angina is characterized by unpredictable attacks of chest pain unrelated to exertion?
Which of the following types of angina is characterized by unpredictable attacks of chest pain unrelated to exertion?
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Which of the following is NOT a characteristic of unstable angina?
Which of the following is NOT a characteristic of unstable angina?
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What is the key difference between a STEMI and a non-STEMI?
What is the key difference between a STEMI and a non-STEMI?
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Which of the following is NOT a complication of acute coronary syndrome?
Which of the following is NOT a complication of acute coronary syndrome?
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Which of the following tests is considered the gold standard for diagnosing myocardial infarction?
Which of the following tests is considered the gold standard for diagnosing myocardial infarction?
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What is a primary characteristic of rheumatic heart disease?
What is a primary characteristic of rheumatic heart disease?
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Which of the following congenital heart defects is characterized by an underdeveloped or malformed tricuspid valve?
Which of the following congenital heart defects is characterized by an underdeveloped or malformed tricuspid valve?
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What is the primary consequence of coarctation of the aorta?
What is the primary consequence of coarctation of the aorta?
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Which of the following congenital heart defects is characterized by the aorta being positioned above the ventricular septal opening?
Which of the following congenital heart defects is characterized by the aorta being positioned above the ventricular septal opening?
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What is the primary effect of left-sided heart failure on the body?
What is the primary effect of left-sided heart failure on the body?
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Which symptom is characteristic of paroxysmal nocturnal dyspnea?
Which symptom is characteristic of paroxysmal nocturnal dyspnea?
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Which of the following conditions does NOT directly impair cardiac output?
Which of the following conditions does NOT directly impair cardiac output?
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What is the primary mechanism by which cardiac tamponade decreases cardiac output?
What is the primary mechanism by which cardiac tamponade decreases cardiac output?
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What is the main cause of cor pulmonale?
What is the main cause of cor pulmonale?
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Which of the following is NOT a characteristic of anaphylactic shock?
Which of the following is NOT a characteristic of anaphylactic shock?
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What is the primary mechanism by which septic shock causes cellular hypoxia?
What is the primary mechanism by which septic shock causes cellular hypoxia?
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What is the most severe form of hypertension and what are its defining characteristics?
What is the most severe form of hypertension and what are its defining characteristics?
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Which of the following is NOT a modifiable risk factor for hypertension?
Which of the following is NOT a modifiable risk factor for hypertension?
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What are some symptoms of hypotension?
What are some symptoms of hypotension?
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Which of the following is NOT a potential end-organ damage caused by hypertension?
Which of the following is NOT a potential end-organ damage caused by hypertension?
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Which blood pressure range is considered to be Stage 1 Hypertension?
Which blood pressure range is considered to be Stage 1 Hypertension?
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What is the DASH diet and what is its role in managing hypertension?
What is the DASH diet and what is its role in managing hypertension?
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What is the role of baroreceptors in the kidneys in regulating blood pressure?
What is the role of baroreceptors in the kidneys in regulating blood pressure?
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Which of the following is a sign of end-organ damage due to hypertension?
Which of the following is a sign of end-organ damage due to hypertension?
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Which of the following lifestyle modifications can help reduce the risk of developing hypertension?
Which of the following lifestyle modifications can help reduce the risk of developing hypertension?
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Which of the following is TRUE about hypertensive urgency?
Which of the following is TRUE about hypertensive urgency?
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Flashcards
Primary Hypertension
Primary Hypertension
Hypertension without a known direct cause; most common form.
Isolated Systolic Hypertension
Isolated Systolic Hypertension
High systolic pressure with stable diastolic pressure.
Isolated Diastolic Hypertension
Isolated Diastolic Hypertension
High diastolic pressure with stable systolic pressure.
Combined Hypertension
Combined Hypertension
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Nonmodifiable Risk Factors
Nonmodifiable Risk Factors
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Modifiable Risk Factors
Modifiable Risk Factors
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Secondary Hypertension
Secondary Hypertension
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End-Organ Damage
End-Organ Damage
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Hypertensive Urgency
Hypertensive Urgency
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Hypertensive Emergency
Hypertensive Emergency
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Symptoms of Hypotension
Symptoms of Hypotension
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Risk Factors for Hypertension
Risk Factors for Hypertension
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Blood Pressure Classification - Normal
Blood Pressure Classification - Normal
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Blood Pressure Classification - Prehypertension
Blood Pressure Classification - Prehypertension
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DASH Diet
DASH Diet
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RAAS Cycle
RAAS Cycle
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Symptoms of Hypertension
Symptoms of Hypertension
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Orthostatic Hypotension
Orthostatic Hypotension
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Causes of Hypotension
Causes of Hypotension
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Pulmonary Stenosis
Pulmonary Stenosis
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Right Ventricular Hypertrophy
Right Ventricular Hypertrophy
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LDL and Coronary Artery Disease
LDL and Coronary Artery Disease
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Aldosterone
Aldosterone
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ACE Inhibitors
ACE Inhibitors
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Sodium and Water Relationship
Sodium and Water Relationship
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Chronic Sodium Consumption
Chronic Sodium Consumption
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Low-Density Lipoproteins (LDL)
Low-Density Lipoproteins (LDL)
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LDL Insudation
LDL Insudation
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Foam Cells
Foam Cells
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Thrombus Formation
Thrombus Formation
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Endothelial Cell Damage
Endothelial Cell Damage
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Stable Angina
Stable Angina
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Unstable Angina
Unstable Angina
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STEMI
STEMI
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NSTEMI
NSTEMI
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Cardiac Tamponade
Cardiac Tamponade
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Rheumatic Heart Disease
Rheumatic Heart Disease
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Atrial Septal Defect
Atrial Septal Defect
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Ventricular Septal Defect
Ventricular Septal Defect
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Patent Ductus Arteriosus
Patent Ductus Arteriosus
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Coarctation of the Aorta
Coarctation of the Aorta
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Left Sided Heart Failure
Left Sided Heart Failure
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Right Sided Heart Failure
Right Sided Heart Failure
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Anaphylactic Shock
Anaphylactic Shock
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Septic Shock
Septic Shock
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Dysrhythmias
Dysrhythmias
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Study Notes
Hypertension
- Primary hypertension is the most common type
- Idiopathic; no direct cause
- Rare in patients under 10
- Three subtypes:
- Isolated systolic hypertension: High systolic, stable diastolic
- Isolated diastolic hypertension: High diastolic, stable systolic
- Combined systolic and diastolic hypertension: Elevated both systolic and diastolic
- Risk factors:
- Nonmodifiable: Age, family history
- Modifiable: Diet, sedentary lifestyle, obesity, metabolic syndrome
- End-organ damage in: Heart (failure), kidneys (failure), eyes (microcirculation damage), brain (hemorrhage)
Secondary Hypertension
- Identifiable condition causing hypertension
- Most common in children under 10 with specific conditions
- Associated with: Renal disease, coarctation of the aorta, pregnancy, obesity, sleep apnea
Hypertensive Urgency vs. Emergency
- Hypertensive urgency: Least severe, sudden increase in BP without end-organ damage. Controlled over 24-48 hrs with medication
- Hypertensive emergency: Severe, sudden increase in BP with end-organ damage. Requires ICU care
End-Organ Damage
- Impairment or damage of major organs due to hypertension
- Examples in:
- Vascular system (endothelial dysfunction, atherosclerosis, arteriosclerotic stenosis, aortic aneurysm)
- Brain (stroke, hemorrhage)
- Heart (left ventricular hypertrophy, chronic heart failure, myocardial infarction)
- Kidneys (albuminuria, proteinuria, chronic renal insufficiency)
Modifiable Risk Factors
- Poor diet high in fat (increases LDL, atherosclerosis)
- Sedentary lifestyle (weakens vasculature, heart)
- Obesity (contributes to hypertension)
- Metabolic syndrome
Blood Pressure Classification
- Normal: <120/<80 mmHg
- Prehypertension: 120-139/80-89 mmHg
- Stage 1 Hypertension: 140-159/90-99 mmHg
- Stage 2 Hypertension: >160/>100 mmHg
Sodium and Hypertension
- RAAS (renin-angiotensin-aldosterone system) initiated with low BP.
- Sodium retention leads to increased water retention, increased blood volume, and increased blood pressure.
- High sodium intake associated with chronic elevation of blood pressure.
ACE Inhibitors
- Inhibit RAAS, reducing blood volume and blood pressure
- Angiotensin I converted to Angiotensin II is prevented. This prevents vasodilation and release of aldosterone
Orthostatic Hypotension Complications
- 20 mmHg drop in blood pressure within 3 minutes.
Hypotension - Causes
- Vasomotor or baroreceptor response issues
- Drug therapy adverse effects
- Arterial stiffness
- Blood volume depletion
Pulmonary Stenosis
- Abnormal fusion of the pulmonary valve cusps.
- Right ventricular hypertrophy occurs
Correlation of LDL and Coronary Artery Disease
- High LDL is not easily broken down and stays in blood for longer
- LDL may damage epithelial cells (inflammation, immune response).
- This leads to endothelial cell and macrophage activity. (Foam cells and thrombus formation).
Stable Angina vs Unstable Angina
- Stable: Predictable chest pain relieved by rest. Usually due to chronic occlusion by atherosclerosis.
- Unstable: Unpredictable, unrelated to exertion. Often due to vasospasm
Complications of Acute Coronary Syndrome
- STEMI (ST-elevation myocardial infarction), identified by ECG.
- NSTEMI (non-ST-elevation myocardial infarction), not clearly shown on an ECG, but can lead to myocardial infarction
- Complications: Heart failure, myocardial infarction, acute kidney failure
Inverted T Waves
- Possible indicator of ischemic myocardial damage.
Rheumatic Heart Disease
- Acute inflammatory disease, typically from beta-hemolytic streptococci.
- Affects connective tissue in joints, heart, and skin.
Congenital Heart Defects
- Atrial Septal Defect (ASD): Opening between atria
- Ventricular Septal Defect (VSD): Opening between ventricles
- Patent Ductus Arteriosus (PDA): Failure of ductus arteriosus closure
- Coarctation of the aorta: Narrowing of the aorta
Left-Sided vs. Right-Sided Heart Failure
- Left-sided: Systemic effects
- Right-sided: Systemic effects
Paroxysmal Nocturnal Dyspnea (PND)
- Difficulty breathing during sleep
Arrhythmias
- Abnormal heart rhythms that interfere with cardiac output
- Possible symptoms: Fatigue, dizziness, lightheadedness
Cardiogenic Shock
- Reduced cardiac output from left ventricular dysfunction
Obstructive Shock
- Reduced cardiac output by physical obstruction.
- Examples: Pulmonary embolus, cardiac tamponade
Distributive Shock (e.g., Anaphylactic Shock)
- Shock with excessive vasodilation and reduced blood pressure.
- Causes: Inflammatory or allergic responses.
- Symptoms: Severe vasodilation, reduced cardiac output.
Sepsis/Septic Shock
- Body's response to severe infection.
- Clotting cascade, complement system, kinin system are triggered.
- Significant vasodilation, hypotension, blood flow maldistribution, cellular hypoxia, edema.
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Description
Test your knowledge on hypertension, including primary and secondary types, risk factors, and the differences between hypertensive urgency and emergency. This quiz covers essential information on causes, effects, and classifications relevant to hypertension-related conditions.