62 Questions
What do hyperkinetic disorders consist of?
Excessive involuntary movements
How are hyperkinetic movements described based on?
Induction, complexity, suppressibility
Which body parts should be identified in the description of a hyperkinetic movement disorder?
The body parts involved in the movement
What type of movements are considered automatic?
Learned motor behaviors performed without conscious effort
What best describes involuntary movements?
Not intentional and rarely suppressible
Which category of movement is induced by an inner sensory stimulus or unwanted feeling?
Semivoluntary
What type of movement disorder is characterized by relatively quick, unpredictable, and dance-like movements of various body parts?
Chorea
Which movement disorder is characterized by sudden brief contractions of a single muscle or body part?
Myoclonus
What movement disorder is described as sustained, involuntary contractions of antagonist muscles in one or more body parts?
Dystonia
Which type of tremor can affect the hands, arms, or head and is usually benign?
Essential tremor
What characteristic distinguishes hyperkinetic dysarthria from other dysarthrias?
Changes speech patterns
Which factor contributes to all hyperkinetic movement disorders interfering with speech production?
Dysfunction in the cerebellar control circuit
What is a common characteristic of hyperkinetic dysarthria?
Involuntary speaking normal at one moment and abnormally the next moment
Which movement disorders can lead to hyperkinetic dysarthria?
Chorea and dystonia
What neurotransmitter imbalance can result in hyperkinesia?
Inhibitory dopamine vs excitatory ACh
What can lesions in the cerebellar structure cause?
Abnormal thalamocortical discharge patterns
What is a characteristic of chorea?
Random, rapid, purposeless movements
What is Huntington's Disease characterized by?
Expansion of CAG repeats in IT 15 gene
What movement patterns are associated with hyperkinetic dysarthria?
Either subtle movements or large obvious movements
What might cause abnormal motor cortex discharges in hyperkinetic dysarthria?
Decrease in dopaminergic activity within the circuit
What is a characteristic feature of Huntington's Disease?
Inherited degenerative CNS disorder
How do individuals with severe chorea try to modify their movements?
By making movements appear intentional to cover them up
In hyperkinetic disorders, the movements are typically characterized by a lack of movement and stiffness.
False
Chorea is a common hyperkinetic disorder characterized by sustained contractions of antagonist muscles in various body parts.
False
Voluntary movements are intentional, planned, or self-initiated.
True
Hyperkinetic movements can be suppressed by volitional attention or sensory tricks.
True
Involuntary movements in hyperkinetic disorders are always fully intentional and suppressible.
False
Dystonia is a common hyperkinetic disorder characterized by sustained contractions of antagonist muscles in one or more body parts.
True
Chorea movements are slow and can be consciously controlled.
False
Myoclonus involves sustained contractions of antagonist muscles in the body parts affected.
False
Tics, such as eye blinks and head jerks, cannot be controlled voluntarily.
False
Dystonia movements are generally faster and more abrupt than choreic movements.
False
Restless leg syndrome causes a crawling sensation that is most prominent during ambulation.
False
Hyperkinetic dysarthria can lead to normal speech execution without any interference from involuntary movements.
False
Hyperkinetic dysarthria is characterized by consistent articulatory precision.
False
Hyperkinetic dysarthria may make functional daily living skills such as walking, eating, and talking nearly impossible.
True
Dyskinesias always result from an imbalance between inhibitory acetylcholine (ACh) and excitatory dopamine.
False
Lesions in the cerebellar structure cannot cause hyperkinetic dysarthria.
False
Chorea is characterized by slow, purposeful, and intentional movements.
False
Huntington's Disease affects the peripheral nervous system.
False
Involuntary movements associated with hyperkinetic dysarthria can interfere with speech production.
True
Hyperkinetic dysarthria may involve subtle movements like large movements of many parts of the body.
True
Individuals with severe chorea can easily suppress their involuntary movements.
False
Dyskinesias in hyperkinetic dysarthria are solely caused by an imbalance in serotonin levels.
False
Match the neurotransmitter with its function in hyperkinesia:
Dopamine = Inhibitory - downer Acetylcholine (ACh) = Excitatory Serotonin = May result in hyperkinesia if imbalanced Norepinephrine = Involved in BG control but role not well understood
Match the characteristic with its description in hyperkinetic dysarthria:
Harshness = One of the vocal characteristics of hyperkinetic dysarthria Variable articulatory imprecision = Speaking normal at one moment and abnormally the next moment Prosodic abnormalities = Include myloklonus then interfere diaphragm and intercostal muscles changing ability to communicate Breathing coordination issues = Resulting from distorted subsystems due to physical movement distortions
Match the movement pattern with its associated disorder:
Purposeless movements interfering with discrete actions = Chorea Volitional modification to cover up movements = Characteristic of severe cases of Chorea Expansion of CAG repeats within IT 15 gene = Huntington's Disease Gradual degeneration of neurons in BG and cerebral cortex = Etiology of Huntington's Disease
Match the type of tremor with its description:
Essential tremor = Action tremor affecting hands, arms, or head; usually benign in nature Resting tremor = Tremor occurring when the affected body part is at rest Postural/sustention tremor = Tremor during maintaining a position against gravity Action/intention tremor = Tremor during voluntary movement towards a target
Match the movement disorder with its associated body parts involved:
Chorea = Limbs, head, face, mouth, and neck Myoclonus = Single muscle or body part affected by sudden contractions Tics = Eye blinks, shoulder shrugs, and head jerks Dystonia = Antagonist muscles in one or more body parts
Match the movement disorder with its characteristic muscle tone fluctuation:
Chorea = Muscle tone fluctuates between hypotonic and hypertonic during one utterance Myoclonus = Sudden contractions cannot be consciously suppressed like hiccups Tics = Motor or vocal behaviors that can be controlled voluntarily Dystonia = Sustained contractions of antagonist muscles come and go in a waxing and waning pattern
Match the hyperkinetic movement disorder with its sensory experience:
Restless leg syndrome = Unpleasant crawling sensation in legs or arms; prominent during relaxation Hyperkinetic Dysarthria = Perceptually distinguishable from other dysarthrias affecting speech production Huntington's Disease = Affects peripheral nervous system causing involuntary movements interfering with speech production Essential Tremor = Action tremor affecting hands, arms, or head; usually benign in nature
Match the following hyperkinetic disorders with their common characteristics:
Restless Leg Syndrome = Causes a crawling sensation most prominent during ambulation Huntington's Disease = Characterized by relatively quick, unpredictable, dance-like movements Dyskinesias = Result from an imbalance between inhibitory acetylcholine (ACh) and excitatory dopamine Tremors = Affect hands, arms, or head and are usually benign
Match the involuntary movement Pattern with its description
Chorea = relatively quick, unpredictable, coordinate movements of the limbs, head, face, mouth, and neck; can have a dance like quality Myoclonus = sudden brief contractions of a single muscle or body part. Tics = motor or vocal behaviors that can be controlled voluntarily Dystonia = sustained, involuntary contractions of antagonist muscles in one or more body parts
Match the involuntary movement pattern with its description.
Restless leg syndrome = an unpleasant, crawling sensation in the legs or arms particularly during sitting and relaxation, it is most prominent in the evening; disappears during ambulation Tremor = an oscillatory, rhythmic movement of one or more body parts Dystonia = sustained, involuntary contractions of antagonist muscles in one or more body parts Tics = motor or vocal behaviors that can be controlled voluntarily
Match the type of movement disorder to its description
Chorea = Characterized by rapid, involuntary, random, purposeless movements of a body part Huntington's disease = Inherited autosomal dominant degenerative CNS disorder Myoclonus = nvoluntary and brief contractions of part of a muscle, a whole muscle, or a group of muscles in the same area of the body. Tics = Throat clearing, grunts, barking, Repetitive eye blinks, facial twitches, grimaces
Match the type of movement disorder to its description
Spasmodic Torticollis = Intermittent dystonic contractions of the neck, resulting in involuntary turning of the head, which is tilted upward Essential Tremor = Benign hyperkinetic movement that causes tremulous movements in affected body parts; an action tremor that disappears at rest Dystonia = sustained, involuntary contractions of antagonist muscles in one or more body parts Spasmodic Dysphonia = Involuntary vocal fold movements during phonation
Match the categorization of dystonia according to body part
Focal = present in only one part of the body Segmental = includes two or more parts of the body Generalized = affects all four limbs and the torso or neck Hemidystonia = affects two or more body parts on the same side of the body
Myoclonus contractions can occur with muscles on the opposite side of the body.
False
Chorea is nearly impossible to suppress.
True
Myoclonus contractions can be consciously suppressed.
False
Tics can be controlled voluntarily.
True
Movements associated with dystonia are typically slower and more prolonged than choreic movements.
True
Study Notes
Hyperkinetic Disorders
- Characterized by excessive involuntary movements
- Too much movement, too little dopamine
- Common disorders include: Restless Leg Syndrome, dystonia, chorea, tics, myoclonus, and tremors
Hyperkinetic Movement Disorders
- Can be described based on:
- How they are induced (stimuli, action, exercise)
- Complexity of the movements (complex or simple)
- Suppressibility (by volitional attention or sensory tricks)
- Description should identify which body parts are involved
Movement Categories Based on Volition
- Automatic: learned motor behaviors without conscious effort
- Involuntary: not intentional, rarely suppressible but can be partially suppressed
- Semivoluntary: movements induced by inner sensory stimulus or unwanted feeling/compulsion
- Voluntary: intentional, planned, or self-initiated
Characteristics of Hyperkinetic Disorders
- Any of the following five involuntary movement patterns can interfere with speech/communication:
- Chorea
- Myoclonus
- Tics
- Dystonia
- Tremor
- Interfere with speech production, resulting in hyperkinetic dysarthria
Chorea
- Relatively quick, unpredictable, coordinate movements of the limbs, head, face, mouth, and neck
- Dance-like quality
- Involuntary, irregular, purposeless, and nonrhythmic
- Movements seem to flow randomly from one body part to another
Myoclonus
- Sudden brief contractions of a single muscle or body part
- "Myo" = single, "Clonus" = contraction
- Contractions can occur singly in a repeating irregular pattern or rhythmically
- Cannot be consciously suppressed
- Examples: hiccups (myoclonus of the diaphragm), jerking as you are falling asleep (myoclonus)
Tics
- Motor or vocal behaviors that can be controlled voluntarily
- Desire to move becomes difficult to suppress
- When the tic occurs, it gives pts momentarily relief
- Examples: motor tics (eye blinks, shoulder shrugs, head jerks), vocal tics (grunting, humming, barking)
Dystonia
- Sustained, involuntary contractions of antagonist muscles in one or more body parts
- Contractions come and go in a waxing and waning pattern
- Two opposite muscle groups = groups fighting, leading to twisted posture
- Very painful, high suicide rate among this patient population
Tremor
- Oscillatory, rhythmic movement of one or more body parts
- Essential tremor: action tremor affecting hands, arms, or head (usually benign)
- Can also result in a voice tremor when the vocal folds are affected
- Types: resting tremor, postural/sustention tremor, action/intention tremor
Restless Leg Syndrome
- Unpleasant, crawling sensation in the legs or arms
- Particularly prominent in the evening, disappears during ambulation
Hyperkinetic Dysarthria
- Perceptually distinguishable from other dysarthrias
- Clinician can make an accurate diagnosis just by observing the individual's movements
- No one underlying symptom, so speech is different in each individual
- Any of the 6 movement disorders can cause a disruption to the 5 subsystems for speech
- Accounts for 6% of all dysarthrias and 5.5% of all motor speech disorders
- Accompanied by hypokinesia disorder
- Definition: difficult to define because it can be caused by many hyperkinetic movement disorders
- Shared factors: caused by dysfunction in the Basal ganglia, portions of the extrapyramidal system, and atypical cerebellar control circuit
- Commonality: all produce involuntary movements that interfere with speech production
- Muscle tone can range from hypotonic to hypertonic, and even fluctuate between the two during one utterance
- Speech gives the impression that normal speech is being executed, but then it is interfered with by regular or unpredictable involuntary movements that distort, slow, or interrupt communication.### Perceptual Characteristics of Hyperkinetic Dysarthria
- Characterized by vocal variability, articulatory imprecision, harshness, and prosodic abnormalities
- Speaking style can change suddenly from normal to abnormal
- Myoclonus can interfere with diaphragm and intercostal muscles, affecting communication
Etiologies of Hyperkinetic Dysarthria
- Several hyperkinetic movement disorders can lead to hyperkinetic dysarthria
- Involuntary movements can vary in severity and type, ranging from barely noticeable to severely impaired daily living skills
Neurological Basis of Dyskinesias
- Dyskinesias can result from an imbalance between excitatory ACh and inhibitory dopamine
- Relative increase in dopaminergic activity or decrease in cholinergic activity within the circuit may result in hyperkinesia
- Other neurotransmitters are involved in basal ganglia (BG) control, but their roles are not well understood
Hyperkinetic Dysarthria and Movement
- Movements can range from subtle (e.g., just lips, hands, or vocal folds) to obvious (e.g., large movements of many body parts)
- Each hyperkinetic disorder has its own unique characteristic movement pattern
Associated Movement Disorders and Diseases
Chorea
- Characterized by rapid, involuntary, random, purposeless movements of a body part
- Can range from mild (appearing restless or jittery) to severe (interfering with walking, swallowing, speech, and other discrete movements)
Huntington's Disease
- Inherited autosomal dominant degenerative CNS disorder
- Caused by gradual degeneration of neurons in the BG and cerebral cortex
- Characterized by expansion of the number of CAG repeats within the IT15 gene, resulting in the enlargement of the Huntingtin protein
- A normal person has a CAG repeat number between 10-28, while those affected by Huntington's have 36 or more
Test your knowledge on hyperkinetic disorders which are characterized by excessive involuntary movements, including conditions like Restless Leg Syndrome and dystonia. Learn about the common hyperkinetic movements and how they are induced.
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