Podcast
Questions and Answers
Which of the following statements about the morphology of Hymenolepis nana is correct?
Which of the following statements about the morphology of Hymenolepis nana is correct?
What is the primary pathogenic effect caused by Hymenolepis nana?
What is the primary pathogenic effect caused by Hymenolepis nana?
Which of the following statements about the morphology of Hymenolepis nana is incorrect?
Which of the following statements about the morphology of Hymenolepis nana is incorrect?
Which of the following is not a characteristic of the eggs of Hymenolepis nana?
Which of the following is not a characteristic of the eggs of Hymenolepis nana?
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What is not a feature of the pathogenesis of Hymenolepis nana?
What is not a feature of the pathogenesis of Hymenolepis nana?
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What is the most common method for diagnosing Fasciola hepatica infection?
What is the most common method for diagnosing Fasciola hepatica infection?
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Which of the following is the recommended treatment for Fasciola hepatica infection?
Which of the following is the recommended treatment for Fasciola hepatica infection?
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Which of the following is NOT a potential pathological effect of Fasciola hepatica infection?
Which of the following is NOT a potential pathological effect of Fasciola hepatica infection?
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Which of the following is NOT an intermediate host for Fasciola hepatica?
Which of the following is NOT an intermediate host for Fasciola hepatica?
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What is the infective stage of Fasciola hepatica that leads to human infection?
What is the infective stage of Fasciola hepatica that leads to human infection?
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Which of the following statements about the life cycle of Fasciola hepatica is correct?
Which of the following statements about the life cycle of Fasciola hepatica is correct?
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What is a characteristic feature of the morphology of the adult Fasciola hepatica?
What is a characteristic feature of the morphology of the adult Fasciola hepatica?
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Which of the following statements about the pathology of Fasciola hepatica infection is incorrect?
Which of the following statements about the pathology of Fasciola hepatica infection is incorrect?
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What is a recommended prevention measure for Fasciola hepatica infection?
What is a recommended prevention measure for Fasciola hepatica infection?
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Which of the following statements about the life cycle of Fasciola hepatica is incorrect?
Which of the following statements about the life cycle of Fasciola hepatica is incorrect?
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Study Notes
Egg Morphology and Clinical Manifestations
- Egg morphology: barrel-shaped, outer and inner shell, transparent polar prominences (polar plugs)
- Clinical manifestations: headache, abdominal pain, dizziness, diarrhea, enteritis due to necrosis of intestinal epithelial cells
Hymenolepis diminuta (Rat Tapeworm)
- Hosts: rats, mice, and other rodents
- Life cycle: ingestion of intermediate host, grain weevil, containing larval stages
- Infests: dried grains, fruits, flour, and cereal
- Morphology: larger than H. nana, scolex with no hooks, eggs with no polar filaments
- Pathology: minimal and non-specific
- Treatment: Praziquantel
Taenia spp. (Tapeworms)
- Two species that infect humans: Taenia saginata and Taenia solium
- Life cycle: infective egg from human feces ingested by cow or pig, oncosphere hatches and penetrates the intestinal mucosa, localizes and encysts in muscle
- Morphology: scolex attaches to human intestine, larva: cysticercus, fluid-filled barrier with an invaginated scolex, eggs of both species are identical
Taenia saginata (Beef Tapeworm)
- MOI: ingestion of cysticercus in cow flesh
- Cysticercus: ovoidal, milky white in color, single scolex invaginated into a fluid-filled barrier
- Morphology:
- Scolex: unarmed with 4 sucking disks
- Gravid proglottids: 1 inch or slightly longer, uterus contains 15-20 primary branches, uterine pore located in a lateral position
- Eggs: identical to T. solium, unsegmented region, high regenerative capacity
- Diagnosis: identify proglottids, eggs, or scolex, perianal swabs, eggs can be differentiated
Hymenolepis nana (Dwarf Tapeworm)
- Most common tapeworm infection in humans
- Definitive host: humans, rodents
- Life cycle: ingestion of embryonated eggs or insects (beetles, fleas) containing larvae, autoinfection: eggs remain in the intestine
- Diagnosis: finding eggs in feces
- Morphology:
- Scolex: 4 sucking disks, short rostellum with hooks
- Proglottid: broader than long, rarely seen in feces specimens
- Body divided into two parts: anterior (long and slender) and posterior (shorter and thicker)
Hookworms (Blood-sucking Nematodes)
- Morphology: large plates in the mouth, adults with large, cylindrical, fusiform bodies, females larger than males
- Pathology: blood loss, anemia, protein loss, rectal prolapse, edematous rectal tissue, inflammation of the colon with hemorrhage
Necator americanus (Hookworm)
- Adults: small, cylindrical, fusiform, gray, females larger than males
- Copulatory bursa: catch, hold female, pair of ventral cutting plates
Ancylostoma duodenale (Hookworm)
- Slightly larger than N. americanus
- Head continuous in the same direction as body curvature
- Two pairs of curved ventral cutting teeth
Metabolism of Ascaris spp.
- Embryos: consume lipid and carbohydrate reserves during first 10 days of development, resynthesize carbohydrate from fat
- Snails: Lymnaea, aquatic plants: Nasturtium officinale (watercress), Ipomea obscura, Ipomea aquatica (kangkong)
Clonorchis sinensis (Chinese Liver Fluke)
- Bile duct and gallbladder of humans and fish-eating mammals (dogs, cats)
- Found in China, Korea, and Japan
- Egg morphology: small protuberance at the abopercular end, ovoid, yellowish to brown in color
- Mode of transmission: ingestion of metacercariae, excysts in the duodenum, attaches to mucosa of bile duct, pancreatic duct, and gallbladder through suckers and embedding in sticky mucus
Fasciola spp. (Liver Flukes)
- Liver and biliary passages of humans and herbivorous mammals (ruminants)
- Mode of transmission: ingestion of metacercariae encysted from edible aquatic plants or by drinking water with floating metacercariae
- Intermediate hosts: snails (Bulimus striatulus, Parafossarulus genera, Thiara granifera, Melanoides tuberculatus)
- Pathology: migrate by penetrating intestinal wall, peri cavity, abdominal wall, diaphragm, and lungs, immature worms settle close to the bronchi, grow, and sexually mature
- Clinical manifestations: granulomatous reaction in the lungs, development of fibrotic encapsulation, pairs of adult worms found in fibrotic capsules or cysts in lungs of infected hosts, chest pain, hemoptysis, myalgia, dyspnea, fever, fatigue
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Description
Test your knowledge on Hymenolepis diminuta, a rat tapeworm that infests rodents and can cause enteritis in heavy infections in humans. Learn about its life cycle, clinical manifestations, pathology, morphology, and treatment with Praziquantel.