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Questions and Answers

What is the primary indicator of unresectability in gastric cancer?

  • Small tumor size
  • Presence of locoregional metastases
  • Vascular involvement of major blood vessels (correct)
  • Patient's age

Which symptom is most characteristic of gastroesophageal reflux disease (GERD)?

  • Dysphagia
  • Weight loss
  • Heartburn (correct)
  • Halitosis

What complication is associated with Barrett's esophagus?

  • Precancerous changes in the esophagus (correct)
  • Aspirin-induced esophagitis
  • Eosinophilic esophagitis
  • Esophageal stricture

What is a typical ALARM symptom in GERD that warrants further evaluation?

<p>Dysphagia (B)</p> Signup and view all the answers

Which diagnostic method is considered gold standard for assessing GERD?

<p>24-hour ambulatory pH monitoring (A)</p> Signup and view all the answers

What therapeutic approach is recommended after assessing alarm symptoms in GERD?

<p>Antacids and H2 receptor blockers (D)</p> Signup and view all the answers

Which symptom may suggest aspiration pneumonia in a GERD patient?

<p>Cough at night (C)</p> Signup and view all the answers

What is a common misdiagnosis for atypical symptoms of GERD?

<p>Asthma (D)</p> Signup and view all the answers

What surgical procedure is considered definitive for chronic pilonidal disease?

<p>Surgical excision of all sinus tracts (D)</p> Signup and view all the answers

What is a common outcome of dumping syndrome following surgery?

<p>Malnutrition (A)</p> Signup and view all the answers

Which symptom is characteristic of pyloric stenosis in infants?

<p>Nonbilious vomiting (D)</p> Signup and view all the answers

What is the normal pH range for acid-base balance?

<p>7.35 - 7.45 (A)</p> Signup and view all the answers

What does an increased PCO2 with a decreased pH indicate?

<p>Respiratory acidosis (B)</p> Signup and view all the answers

Which patient population is most likely to present with pilonidal disease?

<p>Sedentary young adults and patients with obesity (B)</p> Signup and view all the answers

What is the first step in management for an acute pilonidal abscess?

<p>Incision and drainage (B)</p> Signup and view all the answers

What is the recommended dietary approach for patients to manage postoperative complications?

<p>Smaller, more frequent meals (A)</p> Signup and view all the answers

What is the most common cause of urinary tract infections in the hospital setting?

<p>Catheterization (B)</p> Signup and view all the answers

Which treatment is recommended to prevent atelectasis after surgery?

<p>Incentive spirometry (A)</p> Signup and view all the answers

What is the most accurate diagnostic tool for diagnosing thrombophlebitis in the lower leg?

<p>Venography (D)</p> Signup and view all the answers

Which organism is most commonly implicated in postoperative wound infections?

<p>Staphylococcus aureus (A)</p> Signup and view all the answers

What is the typical time frame for the appearance of surgical wound infections?

<p>5-10 weeks (B)</p> Signup and view all the answers

What is the rationale behind continuing chronic narcotics on the day of surgery?

<p>To prevent opioid withdrawal symptoms. (A)</p> Signup and view all the answers

Which of the following is a significant contraindication for surgery?

<p>History of drug abuse. (B)</p> Signup and view all the answers

What is the recommended timeline for smoking cessation prior to surgery?

<p>8 weeks before surgery. (C)</p> Signup and view all the answers

What is an appropriate pharmacological treatment for alcohol dependence?

<p>Naltrexone. (D)</p> Signup and view all the answers

What complication is associated with recent smoking cessation?

<p>Increased respiratory distress. (D)</p> Signup and view all the answers

Which of the following is true regarding the use of patient-controlled anesthesia (PCA) pumps in opioid-abusing patients?

<p>They can risk relapsing the patient to opioid use. (D)</p> Signup and view all the answers

Why are volatile anesthetics concerning for certain patients?

<p>They can mimic alcohol intoxication. (D)</p> Signup and view all the answers

What does the acronym CAGE stand for in screening patients for alcohol use?

<p>Cut down, Annoyed, Guilt, Eye opener. (C)</p> Signup and view all the answers

Which lab tests can be useful for diagnosing or monitoring alcohol use?

<p>MCV and GGT. (D)</p> Signup and view all the answers

What is the correct association regarding sympathomimetic drug use during surgery?

<p>It leads to a greater pressor response during surgery. (A)</p> Signup and view all the answers

What is the main purpose of using multiple methods for prophylaxis in patients at varying risk levels?

<p>To optimize the efficacy based on individual risk profiles (B)</p> Signup and view all the answers

Which factor is NOT considered a significant risk for postoperative kidney function deterioration?

<p>Prolonged surgical duration (A)</p> Signup and view all the answers

What is the recommended fluid calculation for an adult patient over 24 hours?

<p>Patient weight (kg) x 30 (B)</p> Signup and view all the answers

How should postoperative hyperglycemia be managed in diabetic patients?

<p>With IV short-acting insulin or SQ sliding scale insulin (C)</p> Signup and view all the answers

What is the primary strategy for patients with COPD before surgery?

<p>Aim for the best possible baseline respiratory function (D)</p> Signup and view all the answers

Which condition is a contraindication for elective surgery?

<p>Acute lower respiratory tract infection (B)</p> Signup and view all the answers

For patients undergoing procedures requiring catheter placement, which of the following is NOT a suitable indication?

<p>Short, routine surgeries (D)</p> Signup and view all the answers

What is the safest method to manage potassium levels in the post-operative period?

<p>Monitor and replace with IV potassium based on urine output (A)</p> Signup and view all the answers

When is it recommended to use IV insulin for perioperative glucose control?

<p>For rapid adjustments in elevated blood glucose levels (B)</p> Signup and view all the answers

What should be prioritized within the first 24 hours post-surgery regarding potassium?

<p>Avoiding any potassium supplements due to surgery stress (A)</p> Signup and view all the answers

Which of the following is NOT a key feature of substance use disorder?

<p>Use in lower amounts than intended (C)</p> Signup and view all the answers

What should be done for patients on methadone prior to surgery?

<p>Continue methadone use, including the day of surgery (A)</p> Signup and view all the answers

What is a significant predictor for surgical site infections in diabetic patients post-op?

<p>Blood glucose levels over 140mg/dL (A)</p> Signup and view all the answers

What approach should be taken toward patients with a history of smoking before surgery?

<p>Advise stopping smoking at least 8 weeks prior to surgery (B)</p> Signup and view all the answers

What is the most common cause of bloody diarrhea with fever?

<p>Inflammatory bowel disease (IBD) (A)</p> Signup and view all the answers

Which of the following is a common complication associated with diverticulitis?

<p>Intestinal obstruction (C)</p> Signup and view all the answers

What dietary modification is most effective for managing diverticulosis?

<p>High fiber diet (C)</p> Signup and view all the answers

In esophageal neoplasms, what is the primary link to squamous cell carcinoma?

<p>Tobacco and alcohol use (B)</p> Signup and view all the answers

What is the test of choice for diagnosing esophageal webs?

<p>Barium esophagram (C)</p> Signup and view all the answers

What is the most common symptom of gastric carcinoma?

<p>Early satiety (B)</p> Signup and view all the answers

Which risk factor is most strongly associated with gastric cancer?

<p>H. pylori infection (C)</p> Signup and view all the answers

What is often the initial management for a patient with diverticulitis?

<p>Broad spectrum antibiotics (A)</p> Signup and view all the answers

What symptom is most commonly associated with esophageal strictures?

<p>Dysphagia, especially to solids (D)</p> Signup and view all the answers

Which condition is characterized by a transition of squamous to columnar epithelium in the esophagus?

<p>Barrett's esophagus (D)</p> Signup and view all the answers

Which symptom can indicate a complication of squamous cell carcinoma of the esophagus?

<p>Hypercalcemia (B)</p> Signup and view all the answers

What might indicate a diagnosis of c. difficile colitis?

<p>Patient history of recent antibiotic use (C)</p> Signup and view all the answers

Which diagnostic test is most effective for identifying infectious agents in stool?

<p>Stool cultures and microscopy (C)</p> Signup and view all the answers

What is the typical age of onset for diverticular disease?

<p>Over 40 years (A)</p> Signup and view all the answers

Flashcards

Gastric Cancer Resection

Surgical removal of the stomach and regional lymph nodes. Complete removal is ideal for successful treatment.

Unresectability Indicators (Gastric Cancer)

Signs that a tumor cannot be surgically removed, such as vascular or lymph node involvement.

GERD (Gastroesophageal Reflux Disease)

Acid reflux from the stomach into the esophagus causing irritation and damage.

GERD Symptoms (Classic)

Heartburn (pyrosis), regurgitation, dysphagia, or cough. Often post-meal.

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ALARM Symptoms (GERD)

Serious symptoms that require urgent investigation, including dysphagia, odynophagia, weight loss, bleeding.

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GERD Diagnosis

Starts with a clinical history, often confirmed by endoscopy. Ambulatory pH monitoring may be used.

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GERD Treatment (Basic)

Initial: Antacids or H2 blockers. If symptoms persist or alarm symptoms exist, endoscopy is needed.

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Barrett's Esophagus

Precancerous change in esophageal lining; often associated with GERD.

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Gastroenteritis Inflam Type

Bloody diarrhea with fever, dysentery; indicates invasive organisms or IBD (inflammatory bowel disease).

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Diverticulosis

Uninflamed diverticula, often asymptomatic but a cause of lower GI bleeding.

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Diverticulitis

Inflamed diverticula, secondary to obstruction/infection (fecaliths).

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Esophageal Squamous Cell

Cancer type linked to tobacco/alcohol use, hot beverages.

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Esophageal Adenocarcinoma

Cancer type linked to GERD/Barrett's esophagus, obesity.

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Esophageal Strictures

Narrowing of the esophagus.

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Esophageal Webs

Thin membranes in the upper esophagus, possibly congenital.

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Schatzki Ring

Mucosal constrictions in the lower esophagus; often associated with hiatal hernia.

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Gastric Adenocarcinoma

Most common worldwide type of stomach cancer; often diagnosed late in progression.

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H. Pylori

A type of bacteria, often the most important risk factor for gastric cancer.

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Gastric Carcinoma Signs of Mets

Presence of distant cancer spread as indicated by lymph nodes (Virchow's node,etc), or palpable nodule on rectal exam or left axillary lymph node involvement.

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Diverticulitis Diagnostic

CT scan. increased WBCs, +guaiac in stool.

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Esophageal Neoplasms Diagnosis

Upper endoscopy with biopsy; Barrett's esophagus screening every 3-5 years.

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Gastroenteritis fluids

IV fluids are important for management, oral preferred if possible; Bland, low residue (BRAT) diet is supportive

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Gastroenteritis Diagnosis

Stool WBCs indicate presence of inflammation. Cultures, microscopy, and toxin identification may be needed

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Pilonidal Cysts

Infection of skin and subcutaneous tissue near the buttocks, often due to hair follicle inflammation.

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Pilonidal Disease Treatment

Surgical excision of all sinus tracts is the definitive treatment for chronic pilonidal disease.

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Pyloric Stenosis Presentation

Infants initially feed well, but later vomit non-bilious fluids after each or most feedings.

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Pyloric Stenosis Additional Indicators

Infants with pyloric stenosis often have at least three: fever >101.5°F, high heart rate >120, high white blood cells (>10.5 × 10^9), anemia.

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Respiratory Acidosis

Low blood pH due to lungs not removing enough carbon dioxide (high CO2).

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Respiratory Alkalosis

High blood pH due to lungs removing too much carbon dioxide (low CO2).

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Acid-Base Disorders

Disorders of the pH balance in the body, monitored by looking at pH, PCO2, and bicarbonate.

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Post-Surgical Weight Loss Causes

Weight loss after surgery can be due to problems like maldigestion or dumping syndrome, not just the procedure itself.

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Post-op Wound Infection

An infection of a surgical wound, typically appearing 5-10 weeks after surgery, often characterized by fever, pain, redness, drainage, and hardened tissue.

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Nosocomial UTI

A urinary tract infection (UTI) acquired hospital setting

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Common Post-op Infections (Timeframe)

Infections arising within a specific time window from surgery: Wind (atelectasis) First 24-48 hours, Water (UTI) 48-72 hours, Wound (infection) >72 hours

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Common Post-op Infection Organisms

Staphylococcus aureus (Staph) is a frequent culprit in post-surgical wound infections.

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Blood Clots after surgery

Thrombophlebitis, a blood clot in a vein, can be superficial or deep. Diagnosis usually starts with a sonogram.

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Chronic Narcotics Surgery

Continuing narcotic medications on the day of surgery is recommended.

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Alcohol/Drug Screening

Assess alcohol and drug use in all patients (frequency, quantity).

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Acute Intoxication + Surgery

Avoid surgery if possible in cases of acute substance intoxication.

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Smoking & Surgery Risk

Smoking within a year of surgery increases post-operative complications and resource use.

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Smoking Cessation Timing

Optimal smoking cessation should be at least 8 weeks before surgery.

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Nicotine Replacement Therapy

Nicotine replacement may be helpful even the day before surgery.

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Post-op Fever Causes

Post-operative fever can be caused by various factors: infection, environmental changes, etc

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Opioid Use & Analgesia

Predicting opioid needs for pain management is difficult in patients with opioid use disorders.

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Sympathomimetic Drugs & Anesthesia

Patients using sympathomimetic drugs (e.g., cocaine, amphetamines) may have an increased response to anesthetic inducers.

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Volatile Solvents & Surgery

Chronic use of volatile solvents can mimic alcohol intoxication and may cause heart problems.

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Perioperative Bleeding Risk

Increased chance of bleeding during or after surgery, depending on the patient's risk factors.

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Bleeding Prophylaxis

Methods to prevent bleeding during or after surgery (e.g., Fondaparinux, mechanical devices).

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Fluid loss in post-op

Fluid loss in adult patients as insensible/sensible in range of 1500-2500 mL, based on age, gender, and weight.

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Calculating Post-op Fluids

A patient's weight in kg multiplied by 30 gives the approximate fluid needed over 24 hrs, with considerations for other factors.

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Post-op Electrolyte Monitoring

Routine electrolyte checks might not be necessary post-surgery unless unusual fluid loss, sepsis, pre-existing problems, or kidney issues are present.

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Post-op Potassium

Avoid adding potassium in the first 24 hours post-surgery, due to increased levels from surgery stress.

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Preoperative Diabetes Assessment

Patients should be screened for diabetes at admission.

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Perioperative Hyperglycemia

High blood sugar before or after surgery; often treated with IV insulin in diabetic patients.

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Post-op Hyperglycemia Risk

High post-operative blood sugar increases infection risk and longer hospital stays in diabetic patients.

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Smoking Cessation for Surgery

Stopping smoking at least 8 weeks before surgery is optimal to reduce complications.

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COPD and Surgery

Management of COPD prior to surgery, to get to their best possible baseline condition before surgery.

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Asthma and Elective Surgery

Well-controlled asthma poses little risk to elective surgeries but poorly controlled asthma does increase the risk of complications. Need appropriate therapy in these cases.

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Pulmonary Complications

Pulmonary issues are the most common perioperative complications, often related to the surgical site or pre-existing lung conditions.

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Substance Use Disorder and Surgery

A patient's substance use disorder can cause various surgical complications, from issues with access to impaired wound healing and pain management.

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Study Notes

Unresectability in Gastric Cancer

  • Primary indicator: Infiltrative growth pattern of the tumor extending beyond the stomach wall, indicating a spread that cannot be surgically removed.

Gastroesophageal Reflux Disease (GERD)

  • Most characteristic symptom: Heartburn, a burning sensation in the chest that often radiates up to the throat.

Barrett's Esophagus

  • Associated complication: Esophageal adenocarcinoma, a type of cancer that develops in the lining of the esophagus.

ALARM Symptoms in GERD

  • Typical ALARM symptom: Dysphagia (difficulty swallowing), especially if new or progressive, as it suggests a potential obstruction.

Diagnosing GERD

  • Gold standard method: Endoscopy, which allows visualization of the esophagus and detection of any abnormalities.

Managing ALARM Symptoms in GERD

  • Recommended approach: Referral to a specialist for further evaluation and potential biopsy to rule out serious conditions.

Aspiration Pneumonia in GERD

  • Suggestive symptom: Recurrent nighttime cough, especially in the presence of GERD.

Atypical Symptoms of GERD

  • Common misdiagnosis: Anxiety or depression as GERD symptoms can mimic those of mental health conditions.

Chronic Pilonidal Disease

  • Definitive surgical procedure: Pilonidal cystectomy, which involves complete excision of the cyst and surrounding tissue.

Dumping Syndrome

  • Common outcome: Rapid weight loss and nutritional deficiencies due to the body's inability to properly absorb nutrients after surgery.

Pyloric Stenosis in Infants

  • Characteristic symptom: Projectile vomiting, forceful expulsion of milk or formula shortly after feeding.

Acid-Base Balance

  • Normal pH range: 7.35 to 7.45, representing the body's normal acidity.

Increased PCO2 with Decreased pH

  • Indicates: Respiratory acidosis, a condition where the body's ability to eliminate CO2 is impaired, leading to increased acidity.

Pilonidal Disease

  • Most likely patient population: Young adults, particularly males, as the condition is linked to hair growth and friction in the buttocks region.

Acute Pilonidal Abscess

  • First step in management: Incision and drainage of the abscess to relieve pressure and infection.

Postoperative Complications Management

  • Recommended dietary approach: High-protein, low-fiber diet to facilitate healing and minimize digestive disturbances.

Hospital-Acquired Urinary Tract Infections

  • Most common cause: Catheterization, the insertion of a tube into the bladder, creating a pathway for infection.

Preventing Atelectasis after Surgery

  • Recommended treatment: Deep breathing exercises and incentive spirometry to expand the lungs and prevent collapse.

Diagnosing Thrombophlebitis

  • Most accurate tool: Doppler ultrasound, which uses sound waves to detect blood flow and identify blood clots.

Postoperative Wound Infections

  • Most commonly implicated organism: Staphylococcus aureus, a type of bacteria commonly found on the skin.

Surgical Wound Infection Timeline

  • Typical time frame: 4-14 days after surgery, with the majority developing within the first week.

Chronic Narcotics on Surgery Day

  • Rationale: Continuation of pain medications on surgery day helps manage pain and allows the surgical team to assess individual response and adjust doses accordingly.

Contraindication for Surgery

  • Significant contraindication: Uncontrolled bleeding disorders, as these can increase the risk of excessive bleeding during and after surgery.

Smoking Cessation Before Surgery

  • Recommended timeline: 6-8 weeks prior to surgery to allow the body to heal and minimize postoperative respiratory complications.

Alcohol Dependence Treatment

  • Appropriate pharmacological treatment: Medications like naltrexone or acamprosate, which help reduce cravings and prevent relapse.

Recent Smoking Cessation Complication

  • Associated complication: Increased risk of pneumonia due to impaired mucus clearance and airway inflammation.

Patient-Controlled Anesthesia (PCA) Pumps

  • True regarding opioid abusers: PCA pumps can be used but require careful monitoring and dose adjustment due to the potential for misuse and increased risk of overdose.

Volatile Anesthetics Concern

  • Reason: Volatile anesthetics can trigger malignant hyperthermia, a rare but life-threatening condition characterized by rapid muscle breakdown and fever.

CAGE Screening for Alcohol Use

  • Acronym stands for:
    • C: Have you ever felt the need to cut down on your drinking?
    • A: Have people annoyed you by criticizing your drinking?
    • G: Have you ever felt guilty about your drinking?
    • E: Have you ever had a drink first thing in the morning (eye-opener) to steady your nerves or get rid of a hangover?

Lab Tests for Alcohol Use

  • Useful lab tests:
    • GGT (Gamma-glutamyl transferase): A liver enzyme elevated in chronic drinkers.
    • AST (Aspartate aminotransferase) & ALT (Alanine aminotransferase): Liver enzymes that may be elevated in liver damage caused by alcohol.

Sympathomimetic Drug Use During Surgery

  • Correct association: May increase blood pressure and heart rate and can interfere with anesthesia, requiring close monitoring and potentially dose adjustments.

Prophylaxis with Multiple Methods

  • Main purpose: To target different mechanisms and reduce the risk of specific complications, particularly in patients with increased risk factors.

Postoperative Kidney Function Deterioration Risk

  • Factor NOT considered significant: History of seasonal allergies.

Fluid Calculation for Adults

  • Recommended fluid calculation: 30 ml/kg/day, with adjustments based on individual factors like weight, body surface area, and ongoing losses.

Postoperative Hyperglycemia Management in Diabetics

  • Recommended approach: Tight glycemic control through insulin infusion or adjusted oral medication regimens based on blood sugar monitoring.

COPD Patients Before Surgery

  • Primary strategy: Optimization of respiratory function through medication, pulmonary rehabilitation, smoking cessation, and vaccination.

Contraindication for Elective Surgery

  • Contraindication: Unstable medical conditions, such as uncontrolled heart failure or active infections.

Catheter Placement Indication

  • NOT a suitable indication: Performing a routine chest x-ray.

Managing Postoperative Potassium Levels

  • Safest method: Oral potassium supplementation, unless there are underlying conditions that prevent absorption or require urgent correction.

IV Insulin Use for Perioperative Glucose Control

  • Recommended use: When oral medications are insufficient or blood sugar levels require rapid and precise control, particularly in critical care settings.

Potassium Priority in First 24 Hours

  • Prioritization: Monitoring and adjusting the potassium level to prevent hypokalemia (low potassium) and its potential complications, such as cardiac arrhythmias.

Substance Use Disorder Key Features

  • NOT a key feature: Lack of self-control over alcohol use.

Methadone Patients Before Surgery

  • Action to take: Continued methadone dosing according to the established regimen, with potential adjustments guided by individual factors and surgical needs.

Surgical Site Infections in Diabetic Patients

  • Significant predictor: Poor glycemic control, as elevated blood sugar levels weaken the immune system and increase susceptibility to infection.

Approach for Patients with Smoking History

  • Recommendation: Smoking cessation counseling and pharmacologic interventions to help quit prior to surgery and minimize postoperative complications.

Bloody Diarrhea with Fever

  • Most common cause: Clostridium difficile infection (C. difficile colitis), a type of bacterial infection.

Diverticulitis Complication

  • Common complication: Abscess formation, a collection of pus that can develop in the diverticula (outpouchings in the colon).

Diverticulosis Dietary Modification

  • Most effective: High-fiber diet, which helps regulate bowel movements and prevent constipation, a contributing factor to diverticulitis.

Esophageal Squamous Cell Carcinoma

  • Primary link: Tobacco smoking and alcohol consumption are the most significant contributing factors.

Diagnosing Esophageal Webs

  • Test of choice: Esophagoscopy, a procedure using a flexible scope to directly visualize the esophagus and identify webs.

Gastric Carcinoma Symptom

  • Most common: Indigestion or dyspepsia, a general feeling of discomfort or pain in the upper abdomen.

Gastric Cancer Risk Factor

  • Strongest association: Helicobacter pylori infection, a type of bacteria that can colonize the stomach and increase the risk of developing cancer.

Diverticulitis Management

  • Initial management: Primarily focused on conservative measures, such as antibiotics and rest, to treat infection and allow inflammation to subside.

Esophageal Strictures Symptom

  • Commonly associated: Dysphagia (difficulty swallowing), as the narrowing of the esophagus can obstruct food passage.

Barrett's Esophagus

  • Characterized by: Transition of the normal squamous epithelial tissue lining the esophagus to a columnar epithelium similar to the stomach, increasing the risk of esophageal adenocarcinoma.

Squamous Cell Carcinoma Complication

  • Indicative symptom: Dysphagia (difficulty swallowing), especially if progressive and accompanied by weight loss, can be indicative of tumor growth and obstruction.

C. difficile Colitis Indication

  • Indicative of: Recent antibiotic use, as antibiotics can disrupt the gut microbiome and create conditions that allow C. difficile to thrive.

Stool Infectious Agent Identification Test

  • Most effective test: Stool culture, which allows identification of specific infecting organisms and determination of antibiotic resistance.

Diverticular Disease Age of Onset

  • Typical age of onset: Age 40 and above, becoming more common with increasing age.

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