Human Respiratory and Circulatory Systems Quiz
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Questions and Answers

What volume of air is considered the anatomical dead space?

  • 70 ml
  • 500 ml
  • 350 ml
  • 150 ml (correct)
  • What is the tidal volume?

  • 350 ml
  • 700 ml
  • 150 ml
  • 500 ml (correct)
  • What is the volume of air that reaches the alveoli?

  • 700 ml
  • 350 ml (correct)
  • 150 ml
  • 500 ml
  • What is the formula used to calculate the percentage of fresh air reaching the alveoli?

    <p>(Tidal Volume - Anatomical Dead Space) / Tidal Volume x 100% (D)</p> Signup and view all the answers

    What is the percentage of fresh air reaching the alveoli?

    <p>70% (C)</p> Signup and view all the answers

    What is the main function of the respiratory system?

    <p>To exchange oxygen and carbon dioxide between the body and the environment (B)</p> Signup and view all the answers

    Which of the following factors contributes to the decrease in Hb affinity for Oxygen in the tissues?

    <p>Increased partial pressure of carbon dioxide (pCO2) (E)</p> Signup and view all the answers

    What is the name of the electrical signal that triggers a heart beat?

    <p>Action potential (A)</p> Signup and view all the answers

    Which of the following is NOT a component of the structure of the heart?

    <p>Lungs (A)</p> Signup and view all the answers

    What is the difference between the atria and the ventricles of the heart?

    <p>The atria are smaller and receive blood from the body, while the ventricles are larger and pump blood out of the heart. (C)</p> Signup and view all the answers

    What is the function of the pericardium?

    <p>To protect and lubricate the heart (C)</p> Signup and view all the answers

    What are the components of the cardiac cycle?

    <p>Diastole and systole (C)</p> Signup and view all the answers

    Which of the following is NOT a function of the circulatory system?

    <p>Producing hormones that regulate blood pressure (C)</p> Signup and view all the answers

    What is the function of the larynx?

    <p>It regulates the flow of air to the lungs. (A), It is responsible for the production of sound. (C)</p> Signup and view all the answers

    Where does gas exchange occur in the circulatory system?

    <p>In the capillaries of the lungs. (D)</p> Signup and view all the answers

    What is the role of the trachea?

    <p>It connects the larynx to the bronchi. (C)</p> Signup and view all the answers

    Which vessel carries deoxygenated blood to the heart?

    <p>Vena cava (C)</p> Signup and view all the answers

    Which of the following statements is TRUE about the pulmonary artery?

    <p>It carries blood from the heart to the lungs. (C), It carries deoxygenated blood. (D)</p> Signup and view all the answers

    What is the relationship between the pharynx and the larynx?

    <p>The pharynx leads into the larynx. (A)</p> Signup and view all the answers

    Which of the following is NOT a part of the respiratory system?

    <p>Esophagus (C)</p> Signup and view all the answers

    Why is the pulmonary vein considered a vein even though it carries oxygenated blood?

    <p>The pulmonary vein carries blood from the lungs to the heart. (D)</p> Signup and view all the answers

    What is the primary role of the circulatory system in the respiratory process?

    <p>To pump blood to the lungs for gas exchange. (C)</p> Signup and view all the answers

    What is the primary function of the nasal cavity in the respiratory process?

    <p>All of the above. (D)</p> Signup and view all the answers

    What is the key difference in excitation-contraction coupling between skeletal and cardiac muscle?

    <p>Skeletal muscle relies on direct interaction between transverse tubules and the sarcoplasmic reticulum (SR), while cardiac muscle uses Ca2+-induced Ca2+ release. (B)</p> Signup and view all the answers

    What is the structure of myocardial cells?

    <p>Short, branched, and interconnected, with electrical synapses (gap junctions). (C)</p> Signup and view all the answers

    What is a key characteristic of cardiac muscle that distinguishes it from skeletal muscle?

    <p>Cardiac muscle is capable of producing its own action potentials automatically, while skeletal muscle requires external stimulation. (B)</p> Signup and view all the answers

    What is the significance of the presence of gap junctions in myocardial cells?

    <p>Gap junctions allow for the rapid and coordinated spread of electrical signals throughout the heart. (B)</p> Signup and view all the answers

    Which of these statements is TRUE regarding taurine?

    <p>Taurine deficiency can contribute to heart problems in both humans and animals. (D)</p> Signup and view all the answers

    What is the key role of ATP in the process of muscle contraction?

    <p>ATP provides energy for the activation of the myosin head and its change in orientation (A), ATP is used to break the bond between myosin and actin after the power stroke (D)</p> Signup and view all the answers

    What is the function of the troponin complex in muscle contraction?

    <p>To regulate the exposure of actin binding sites for myosin (A)</p> Signup and view all the answers

    What is the direct consequence of calcium ions binding to troponin in muscle contraction?

    <p>The troponin-tropomyosin complex moves, exposing binding sites on actin for myosin (A)</p> Signup and view all the answers

    What is the role of the myosin head in the muscle contraction process?

    <p>To bind to actin, undergo a power stroke, and detach from actin (C)</p> Signup and view all the answers

    How does the concentration of calcium ions in the muscle cell influence the contraction process?

    <p>High calcium concentrations inhibit the binding of myosin to actin (A)</p> Signup and view all the answers

    What is the key difference between skeletal muscle and cardiac muscle contraction, based on the provided information?

    <p>Skeletal muscle requires external stimulation by somatic motor nerves, while cardiac muscle is stimulated by the autonomic nervous system (B)</p> Signup and view all the answers

    What is the main function of the myosin filaments in muscle contraction?

    <p>To bind to actin and generate the power stroke during muscle contraction (A)</p> Signup and view all the answers

    According to the provided information, what happens when the concentration of calcium ions in the muscle cell decreases?

    <p>The muscle fiber relaxes (B)</p> Signup and view all the answers

    What is the name of the protein that anchors thin filaments in muscle cells?

    <p>Z-disc (A)</p> Signup and view all the answers

    What is the name of the protein that is responsible for the contraction of muscles?

    <p>Myosin (A)</p> Signup and view all the answers

    What is the name of the section of the muscle fiber between two Z-discs?

    <p>Sarcomere (D)</p> Signup and view all the answers

    Which of the following is NOT a characteristic of a myofibril?

    <p>Located within the sarcolemma (B)</p> Signup and view all the answers

    How does the arrangement of thin and thick filaments contribute to the striated pattern of muscle fibers?

    <p>The different protein compositions of the thin and thick filaments create the dark and light bands. (B)</p> Signup and view all the answers

    What is the name of the light band in the sarcomere?

    <p>I-band (A)</p> Signup and view all the answers

    What is the name of the narrow light band in the center of the A-band?

    <p>H-zone (D)</p> Signup and view all the answers

    What is the role of troponin in muscle contraction?

    <p>Troponin binds to calcium and moves tropomyosin away from the myosin binding sites. (C)</p> Signup and view all the answers

    What is the name of the protein molecule that is attached to actin and blocks myosin binding sites in a relaxed muscle?

    <p>Tropomyosin (A)</p> Signup and view all the answers

    What is the role of the myosin head in muscle contraction?

    <p>The myosin head binds to actin and pulls the thin filament toward the center of the sarcomere. (D)</p> Signup and view all the answers

    Which of the following events occurs first during muscle contraction?

    <p>Calcium ions bind to troponin. (B)</p> Signup and view all the answers

    What is the role of ATP in muscle contraction?

    <p>All of the above. (D)</p> Signup and view all the answers

    What is the term for the sliding of thin and thick filaments past each other during muscle contraction?

    <p>Sliding filament theory (A)</p> Signup and view all the answers

    What is the name of the structure that surrounds individual muscle fibers?

    <p>Sarcolemma (C)</p> Signup and view all the answers

    Which of the following is TRUE about the H-zone during muscle contraction?

    <p>The H-zone gets smaller. (D)</p> Signup and view all the answers

    Which of the following is NOT a factor that affects the force of muscle contraction?

    <p>The type of muscle fibers present (D)</p> Signup and view all the answers

    Flashcards

    Anatomical Dead Space

    The volume of the respiratory system that doesn't participate in gas exchange.

    Tidal Volume

    The amount of air inhaled or exhaled during normal breathing.

    Fresh Air Reaching Alveoli

    The portion of inhaled air that participates in gas exchange in the lungs.

    Calculation of Fresh Air Percentage

    The method to determine the percentage of fresh air entering the alveoli.

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    Gas Exchange

    The process of oxygen and carbon dioxide transfer between the alveoli and blood.

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    Hb Affinity for Oxygen

    The tendency of hemoglobin to bind with oxygen; decreased affinity means hemoglobin releases oxygen more readily.

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    O2 Movement in Lungs

    The process of oxygen entering the bloodstream from the alveoli in the lungs during breathing.

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    CO2 Movement in Tissues

    The process of carbon dioxide being released from tissues into the bloodstream for exhalation.

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    Circulatory System Distribution

    How blood is allocated throughout the body, varying during different activity levels.

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    Structure of the Respiratory System

    Anatomical components including trachea, bronchi, and alveoli facilitating gas exchange.

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    Mechanics of Breathing

    The physical actions of inhalation and exhalation involving diaphragm and intercostal muscles.

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    Electrical Activity of the Heart

    The sequence of electrical impulses that trigger heartbeats, controlling the heart rhythm.

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    Cardiac Cycle

    The sequence of events in one heartbeat including contraction (systole) and relaxation (diastole).

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    Pharynx

    A muscular passage that connects the nasal cavity to the larynx.

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    Larynx

    The voice box that diverts air to the lungs and food to the esophagus.

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    Trachea

    The tube that carries air from the larynx to the lungs.

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    Bronchus

    Branches from the trachea leading to the lungs.

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    Pulmonary artery

    Carries deoxygenated blood from the heart to the lungs.

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    Pulmonary vein

    Carries oxygenated blood from the lungs to the heart.

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    Vena cava

    Large vein carrying deoxygenated blood to the right atrium of the heart.

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    Right atrium

    The chamber that receives deoxygenated blood from the body.

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    Left atrium

    The chamber that receives oxygenated blood from the lungs.

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    Capillary beds

    Networks of small blood vessels where gas exchange occurs.

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    SA Node

    The natural pacemaker of the heart that produces action potentials automatically.

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    Myocardial Cells

    Short, branched, and interconnected heart muscle cells forming the heart myocardium.

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    Skeletal Muscle Contraction

    Direct excitation-contraction coupling via transverse tubules and SR in skeletal muscles.

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    Cardiac Cell Ca2+ Release

    In cardiac cells, Ca2+ channels don't directly interact; it involves Ca2+-induced Ca2+ release.

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    Taurine in Diet

    Cats need taurine in their diet to prevent heart failure; humans do not produce it.

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    Myosin Head

    The part of myosin that binds to actin and ATP.

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    ATP Hydrolysis

    The process where ATP is broken down to ADP, activating myosin.

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    Troponin Complex

    A protein complex that has 3 subunits, attached to tropomyosin.

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    Tropomyosin

    A protein that, together with troponin, regulates actin's access to myosin.

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    Calcium Ion (Ca2+)

    A crucial ion that binds with troponin, triggering muscle contraction.

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    Power Stroke

    The action where myosin pulls actin, shortening the muscle.

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    Cardiac Muscle vs Skeletal Muscle

    Cardiac muscle contracts with intrinsic signals; skeletal needs external nerve signals.

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    Excitation-Contraction Coupling

    The process linking muscle excitation to contraction.

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    Myocardial cell relaxation

    The process where myocardial cells return to a relaxed state after contraction.

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    Myofibrils

    Long, rod-shaped organelles in muscle fibers that facilitate contraction.

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    Striated pattern

    The alternating light and dark bands observed in myofibrils due to actin and myosin arrangement.

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    Z-discs

    Protein structures that act as anchors for thin filaments in a sarcomere.

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    Sarcomere

    The section of muscle fiber between two Z-discs, functioning as the basic unit of contraction.

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    Thin filaments

    Protein strands primarily composed of actin, involved in muscle contraction.

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    Thick filaments

    Proteins, primarily myosin, that interact with thin filaments for muscle contraction.

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    Actin

    A protein that makes up thin filaments in muscle fibers and facilitates contraction.

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    Myosin

    A protein that forms thick filaments in muscle fibers and has heads that pivot for contraction.

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    I-bands

    Light bands in a striated muscle, which contain only thin filaments.

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    A-bands

    Dark bands in a striated muscle, containing thick and some thin filaments.

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    H-zone

    The central region of the A-band where only thick filaments are present.

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    Contraction mechanism

    The process by which thick and thin filaments slide past each other, shortening the sarcomere.

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    Study Notes

    Important Dates for BIOM*3200

    • Practice test 1 (from last year) is now available.
    • Ask your TA if you have any questions about the practice test.
    • Tuesday, January 21: CV lecture 1
    • Thursday, January 23: CV lecture 2
    • Friday, January 24: Office hours
    • Monday, January 27: Office hours
    • Tuesday, January 28: CV lecture 3 – Distinguished Clinician Scientist
    • Thursday, January 30: Test #1

    Cardio-Respiratory: Version 12

    • Distribution of blood (blood pie chart): 449
    • Structure of the respiratory system: 525-527
    • Physical properties of lungs to mechanics of breathing: 530-533
    • Lung volumes and capacities: 535-536
    • Oxygen toxicity, nitrogen narcosis, hyperbaric oxygen therapy, decompression sickness: 545-546
    • Hemoglobin: 552
    • Carbon dioxide transport to ventilation and acid-base balance: 558-560
    • High altitude to the end of the chapter: 563-566

    Cardio-Respiratory: Version 13

    • Distribution of blood (blood pie chart): 455
    • Structure of the respiratory system: 533-535
    • Physical properties of lungs to pulmonary disorders: 538-544.
    • Disorders caused by High Partial Pressures of Gases: 552-553
    • Hemoglobin: 559
    • Carbon dioxide transport to ventilation and acid-base balance 565-568
    • High altitude to the end of the chapter: 571-573

    Cardio-Respiratory: Version 14

    • Distribution of blood (blood pie chart): 455
    • Structure of the respiratory system: 533-535
    • Physical properties of lungs to pulmonary disorders: 538-544
    • Disorders caused by High Partial Pressures of Gases: 552-553
    • Hemoglobin: 559
    • Carbon dioxide transport to ventilation and acid-base balance: 565-568
    • Respiratory adaptations to high altitude: 573

    Cardio-Respiratory: Version 15

    • Distribution of blood (blood pie chart): 455
    • Structure of the respiratory system: 533-535
    • Disorders caused by High Partial Pressures of Gases: 536-544
    • Hemoglobin: 559
    • Carbon dioxide transport to ventilation and acid-base balance: 565-568
    • Respiratory adaptations to high altitude: 573

    Cardio-Respiratory: Version 16

    • Distribution of blood (blood pie chart): 454
    • The respiratory system (section 16.1): 532-535
    • Physical properties of lungs to pulmonary disorders: 537-543
    • Disorders caused by High Partial Pressures of Gases: 551-552
    • Hemoglobin: 558-559
    • Carbon dioxide transport to acid-base balance: 564-566
    • Acclimatization to high altitude: 570

    Learning Objectives

    • Distribution of blood at-rest in the circulatory system
    • Structure of the respiratory system
    • Physical aspects of ventilation
    • Mechanics of breathing
    • Hemoglobin and Oxygen transport

    Distribution of Blood in the Circulatory System at Rest

    • The venous system contains most of the blood.
    • It acts as a reservoir storing blood that can be released to the circulatory system during exercise or other appropriate conditions.

    Structure of Blood Vessels

    • Arteries provide resistance to blood flow from the heart.
    • Veins can expand as they accumulate blood.
    • The average pressure in veins is only 2 mmHg compared to 100 mmHg average arterial pressure.

    Veins

    • Venous pressure is too low to return blood to the heart.
    • Skeletal muscle groups help return lower limb blood to the heart via contractions, this is called the "skeletal muscle pump".
    • Breathing, abdominal and thoracic contractions help also to return venous blood to the heart

    Arteries

    • The elastic recoil of large elastic arteries maintains blood flow during the diastolic phase when the heart is resting.
    • Small arteries and arterioles are less elastic.
    • Their size changes slightly.

    Capillaries

    • There are over 40 billion capillaries in the body, meaning every cell is very close to a capillary.
    • Capillaries have walls composed of a single cell layer, making exchange of materials between blood and tissues easier.
    • Vasoconstriction decreases blood flow, and vasodilation increases it.

    More about Capillaries

    • Blood pressure forces fluid out of the capillary at the arterial end.
    • Osmotic pressure draws fluid back into the capillary at the venous end

    Air Passageways

    • The nasal cavity leads to the pharynx (throat) which leads to the larynx.
    • The larynx is where air diverts to the lungs and food to the esophagus.
    • The larynx also contains folds called vocal cords.

    The Pharynx and the Larynx

    • The nasal cavity leads to the pharynx, a muscular passage connecting the nasal cavity to the larynx.
    • The larynx is the part of the throat where air travels to the lungs and food passes the esophagus.
    • The larynx contains structures called the vocal cords.

    The Respiratory System

    • The respiratory system's components include the trachea, bronchi, and the lungs.
    • The respiratory system facilitates gas exchange (intake of oxygen, release of carbon dioxide).

    Physical Properties of the Lungs: Inspiration and Compliance

    • Lungs must be compliant (stretchable) to expand during inhalation.
    • Lung compliance is measured as the change in lung volume per unit change in transpulmonary pressure.
    • Lung diseases can reduce compliance

    Physical Properties of the Lungs: Expiration and Elasticity

    • To exhale, the lungs must shrink when tension is released, which requires elasticity.
    • Elasticity, due to elastin proteins, allows the lungs to return to their initial size after being stretched.
    • Lungs are normally attached to the chest wall, resulting in elastic tension during respiration.

    Lungs are Normally Attached to the Chest Wall

    • Lungs are attached to the chest wall via pleural membranes, which consist of a layer attached to the lung surface and another attached the inner chest wall.
    • They generate a mucous-rich, lubricating fluid to allow them to slide easily within the thoracic cavity.

    The Pleural Membranes

    • The pleural fluid holds the two pleural membranes together.
    • The pleural fluid acts as a lubricant, making the lungs able to slide easily within the thoracic cavity.

    Physical Properties of the Lungs: Surface Tension

    • Surface tension is exerted by fluid in the alveoli (air sacs).
    • The alveolar fluid contains surfactant, a mixture of phospholipids and surfactant proteins.
    • This surfactant reduces surface tension, preventing the alveoli from collapsing.

    Physical Properties of the Lungs: Respiratory Distress Syndrome

    • Premature babies may be born with insufficient surfactant.
    • This causes the alveoli to collapse, making it hard to breathe.

    Physical Properties of the Lungs: Lung Volumes and Capacities

    • Tidal volume (volume of air breathed in and out in a normal breath).
    • Inspiratory reserve volume (the volume of air inspired from rest to maximal inspiration).
    • Expiratory reserve volume (the volume of air that can be expired from rest to maximal exhalation).
    • Residual volume (the volume of air remaining in the lungs after the expiratory reserve volume is expelled).

    Anatomical Dead Space

    • Nose, mouth, larynx, trachea, bronchi, and bronchioles are areas where no gas exchange occurs.
    • Anatomical dead space is approximately 150 ml.

    Critical Thinking Questions

    • Zombies (Walking Dead) & Vampires (Twilight): How does the percentage of fresh air reaching the alveoli change under fictional conditions of inspiration?

    The Role of Hemoglobin

    • Hemoglobin is an iron-containing protein in red blood cells.
    • It binds to oxygen (O2), acting as a transport protein from the lungs to body tissues.
    • Hemoglobin is very effective at carrying and releasing oxygen due to its chemical properties. 

    Carbon Dioxide/Oxygen Transport in Blood

    • CO2 diffuses from the blood to the alveoli in the lungs, and from body tissues to the blood.
    • CO2 levels are low in the blood of the lungs, which will result in less acidity.
    • CO2 levels are high in the blood of body tissues, which will result in higher acidity.
    • Hemoglobin also binds to CO2.
    • Carbonic anhydrase is an enzyme that catalyzes the conversion of CO2 to bicarbonate (HCO3-) in red blood cells.

    O₂ Uptake in the Lungs

    • O₂ dissolves into the fluid lining the alveoli
    • Moves from the alveoli to blood capillaries
    • Combines with hemoglobin to form oxyhemoglobin.
    • Oxyhemoglobin formation occurs in the lungs because blood CO₂ levels are low.

    O₂ Release in the Tissues

    • Oxygen (O2) is released from oxyhemoglobin and diffuses into body tissues.
    • Dissociation occurs because plasma CO2 levels are high and pH goes down in body tissue, this is also referred to as becoming more acidic.

    CO₂ Transport

    • CO₂ is transported in the blood mostly as bicarbonate (HCO3−) .
    • A small amount is carried chemically attached to hemoglobin.

    Electrical Activity of the Heart

    • Sinoatrial node (SA node) is the heart's pacemaker.
    • Atrioventricular node (AV node) temporarily delays the electrical signal from the atria to ventricles.
    • Purkinje fibers spread electrical signal throughout the ventricles.

    The Electrocardiogram (ECG)

    • The signals are recorded from the body by electrodes, and form the waveform of a complex, compound action potential.

    Coronary Artery Disease

    • Plaque buildup in the coronary arteries reduces blood flow to the heart.
    • This can cause chest pain or angina.

    Myocardial Infarction

    • The complete blockage of blood flow can result in a myocardial infarction, or heart attack.
    • Interruption to blood flow results in the death of heart muscle cells (myocardial cells).

    ECG & Heart Disease

    • An electrocardiogram or ECG, is a test to measure the electrical activity of the heart.
    • Irregularities in the waveforms (e.g., ST-segment depression, prolonged PR interval, or QRS complex) can suggest underlying cardiac problems.

    Tachycardia (Abnormal Heartbeat)

    • Rapid heart rate, >100 bpm.
    • Symptoms can include palpitations, shortness of breath, dizziness, and chest pain.

    Bradycardia (Abnormal Heartbeat)

    • Slow heart rate, < 60 bpm.
    • Symptoms can include lightheadedness, fatigue, and fainting

    Cardiac Muscle

    • Cardiac muscle cells are short, branched, and interconnected.
    • These cells contract in a coordinated way due to unique electrical synapses (gap junctions)
    • The cells are striated, but contractions are involuntary.

    Excitation-Contraction Coupling in Cardiac Muscle

    • Voltage-gated calcium channels open and allows calcium to diffuse to the cytoplasm
    • The diffusion of Ca2+ activates the Ca2+ release channels in the sarcoplasmic reticulum (SR); in this way, calcium (Ca2+) in the sarcoplasmic reticulum stimulates contraction.
    • Ca2+-ATPase pumps calcium back into the SR to allow the cardiac muscle to relax. 

    Microanatomy of Muscle

    • Muscle fibres are arranged into thick (myosin) and thin (actin) filaments.
    • Z-discs act as anchors for thin filaments in the I-band.
    • The A-band is comprised of thick filaments and portions of thin filaments.
    • The H-zone is the centre of the A-band.

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    Description

    Test your knowledge on the human respiratory and circulatory systems with this quiz. Questions cover topics such as anatomical dead space, tidal volume, heart structure, and gas exchange. Perfect for students studying biology or health sciences.

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