Human Digestion Process
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Questions and Answers

Match the following organs with their primary functions:

Liver = Detoxification and bile production Gallbladder = Storage and concentration of bile Pancreas = Production of digestive enzymes Kidney = Filtration of blood to form urine

Match the following parts of the nephron with their functions:

Glomerulus = Site of blood filtration Proximal convoluted tubule = Reabsorption of water and nutrients Loop of Henle = Creation of concentration gradient Collecting duct = Final water reabsorption

Match the following digestive enzymes with what they break down:

Disaccharidases = Break down disaccharides into monosaccharides Peptidases = Break down proteins into peptides Endopeptidase = Cleaves peptide bonds within proteins Brush-border enzymes = Facilitate nutrient absorption in the intestine

Match the following hormones with their roles:

<p>Aldosterone = Regulates sodium and potassium levels Antidiuretic hormone (ADH) = Regulates water reabsorption Renin = Helps regulate blood pressure Insulin = Regulates blood glucose levels</p> Signup and view all the answers

Match the following processes with their descriptions:

<p>Filtration = Process of blood being filtered in the nephron Reabsorption = Absorption of useful substances back into blood Secretion = Active transport of substances into nephron tubules Osmoregulation = Regulation of fluid and ion balance in the body</p> Signup and view all the answers

Match the following sections of the nephron with their characteristics:

<p>Ascending loop of Henle = Permeable to ions but not water Descending loop of Henle = Permeable to water Distal convoluted tubule = Fine-tuning of electrolyte balance Renal capsule = Fibrous covering of the kidney</p> Signup and view all the answers

Match the following anatomical terms with their definitions:

<p>Cortex = Outer region of the kidney Medulla = Inner part of the kidney Bowman's capsule = Surrounds the glomerulus in the nephron Starling's forces = Regulate fluid movement across capillary walls</p> Signup and view all the answers

Match the following components of the enteric nervous system with their functions:

<p>Anal sphincters = Control opening and closing of the anus Enteric nervous system = Regulates gastrointestinal function independently Albumin = Transports substances in the bloodstream Bile = Aids in digestion and absorption of fats</p> Signup and view all the answers

Match the following digestive structures with their functions:

<p>Small intestine = Site of major nutrient absorption Large intestine = Water absorption and feces storage Stomach = Acidic digestion of food Esophagus = Transports food to the stomach</p> Signup and view all the answers

Match the following kidney functions with their corresponding processes:

<p>Filtration = Initial blood processing in nephron Reabsorption = Returns nutrients to the bloodstream Secretion = Elimination of waste products Concentration = Adjustment of urine concentration</p> Signup and view all the answers

Match the digestive processes with their descriptions:

<p>Mastication = The physical action of chewing food Peristalsis = Wavelike contractions that move food through the digestive tract Chyme = Semi-fluid mass of partially digested food Mechanical digestion = Physical breakdown of food into smaller particles</p> Signup and view all the answers

Match the enzymes with their functions:

<p>Salivary amylase = Begins the breakdown of starches Salivary lipase = Initiates the digestion of fats Pepsin = Breaks down proteins into smaller peptides Gastrin = Stimulates the secretion of gastric acid</p> Signup and view all the answers

Match the organs with their roles in digestion:

<p>Stomach = Mixes food with gastric juices Esophagus = Carries food from mouth to stomach Pharynx = Connects nasal cavity and mouth to esophagus Small intestine = Absorbs nutrients from digested food</p> Signup and view all the answers

Match the cells with their secretions:

<p>Parietal cells = Produce hydrochloric acid Chief cells = Secrete pepsinogen Mucus cells = Produce protective secretions Gastrin-secreting cells = Regulate gastric acid secretion</p> Signup and view all the answers

Match the nutrients with their absorption mechanisms:

<p>Fat-soluble vitamins = Absorbed through lacteals in the small intestine Proteins = Broken down and absorbed as amino acids Carbohydrates = Converted to sugars and absorbed in the intestine Fats = Emulsified and absorbed via lymphatic system</p> Signup and view all the answers

Match the digestive terms with their meanings:

<p>Bolus = Rounded mass of food ready to be swallowed Gut flora = Microorganisms aiding in digestion Microvilli = Increase surface area for nutrient absorption Chyme = Partially digested food mixed with gastric juices</p> Signup and view all the answers

Match the digestive hormones with their functions:

<p>Gastrin = Stimulates gastric acid production Secretin = Regulates acid and bicarbonate levels Cholecystokinin = Stimulates bile and pancreatic juice secretion Insulin = Regulates blood sugar levels</p> Signup and view all the answers

Match the types of digestion with their processes:

<p>Mechanical digestion = Involves physical actions like chewing Chemical digestion = Involves enzymatic breakdown of food Absorption = Process of nutrients entering the bloodstream Defecation = Elimination of indigestible substances</p> Signup and view all the answers

Match the components of the digestive system with their structures:

<p>Esophagus = Muscular tube from mouth to stomach Stomach = Organ for mixing food and gastric juices Small intestine = Site of major nutrient absorption Large intestine = Absorbs water and forms waste</p> Signup and view all the answers

Match the digestive disorders with their descriptions:

<p>Acid reflux = Backflow of stomach acid into the esophagus Gastritis = Inflammation of the stomach lining Celiac disease = Intolerance to gluten leading to damage in the small intestine Irritable bowel syndrome = Affects the large intestine, causing cramping and bloating</p> Signup and view all the answers

Match the following gel electrophoresis techniques with their descriptions:

<p>SDS-PAGE = Uses SDS to denature proteins and add negative charges Native-PAGE = Retains protein structure without denaturing Isoelectric focusing = Separates proteins by their isoelectric point Reducing SDS-PAGE = Uses a reducing agent to break disulfide bonds</p> Signup and view all the answers

Match the following chromatography types with their characteristics:

<p>Gel filtration chromatography = Separates substances by size using small pores Ion-exchange chromatography = Separates substances based on charge Anion-exchange chromatography = Attracts negatively charged molecules Cation-exchange chromatography = Attracts positively charged molecules</p> Signup and view all the answers

Match the following blotting techniques with their target molecules:

<p>Northern blot = RNA Southern blot = DNA Western blot = Protein Eastern blot = Post-translational modifications</p> Signup and view all the answers

Match the following terms related to DNA with their definitions:

<p>Sanger method = Determines the sequence of a DNA strand Primer = Necessary for initiating DNA replication Reverse transcriptase = Produces DNA that is complementary to RNA cDNA library = Collection of cells storing genes of interest</p> Signup and view all the answers

Match the following components of ELISA with their roles:

<p>Direct ELISA = Determines if an antibody binds to an immobilized antigen Indirect ELISA = Uses secondary antibody linked to reporter enzyme Sandwich ELISA = Measures antigen concentration using two antibodies Reporter = Signals the presence of a substance</p> Signup and view all the answers

Match the following components of a centrifugation process with their descriptions:

<p>Pellet = Solid region at the bottom of a centrifuged tube Supernatant = Liquid region at the top of a centrifuged tube Centrifugation = Separating substances by spinning at high speeds Elute = Break interaction to exit the column</p> Signup and view all the answers

Match the following definitions with the appropriate terms:

<p>Charge density = Amount of charge per area of a molecule Disulfide bond = Covalent bond between two cysteine residues Denature = Unfold a protein Isoelectric point (pI) = pH where net charge of a protein is zero</p> Signup and view all the answers

Match the following genetic manipulation techniques with their purposes:

<p>Bacterial transformation = Absorbing genetic information from surroundings Restriction enzymes = Cut specific sequences of DNA Plasmids = Circular pieces of DNA used for cloning Polymerase chain reaction (PCR) = Generates many copies of a DNA piece</p> Signup and view all the answers

Match the following techniques with their applications:

<p>Western blot = Identifies specific proteins Southern blot = Identifies specific DNA strands Northern blot = Identifies specific RNA strands Affinity chromatography = Isolates specific substances using high affinity</p> Signup and view all the answers

Match the following terms related to chromatography with their definitions:

<p>Mobile phase = Liquid containing substance of interest Stationary phase = Immobilized part that attracts substances Affinity chromatography = Uses a stationary phase with affinity for the substance Elution = Releases substance from stationary phase</p> Signup and view all the answers

Match the following components of bone structure with their functions:

<p>Osteons = Basic structural units of compact bone Haversian canals = Contain blood vessels Lacunae = House mature bone cells Volkmann’s canals = Connect Haversian canals</p> Signup and view all the answers

Match the following bone cells with their roles:

<p>Osteoblasts = Responsible for bone growth Osteoclasts = Resorb bone matrix Osteocytes = Maintain bone tissue</p> Signup and view all the answers

Match the following types of ossification with their processes:

<p>Intramembranous ossification = Occurs in flat bones Endochondral ossification = Forms long bones from a cartilage model Osteoblasts = Secrete osteoid for bone formation Cartilage model = Calcifies to form primary ossification centers</p> Signup and view all the answers

Match the following parts of the skin with their descriptions:

<p>Epidermis = Outermost layer of the skin Dermis = Contains sweat glands and hair follicles Hypodermis = Stores adipose tissue and connects to muscles Piloerection = Raising of hairs to trap heat</p> Signup and view all the answers

Match the following muscle-related processes with their descriptions:

<p>Power stroke = Shortening of the sarcomere Shivering = Generates heat through muscle contraction Thermoregulation = Maintains stable internal temperature Sarcoplasmic reticulum = Stores high concentrations of Ca2+</p> Signup and view all the answers

Match the following connective tissues with their components:

<p>Tendons = Attach muscles to bones Ligaments = Connect bone to bone Collagen = Forms structure of tendons and ligaments Yellow bone marrow = Fat-storing tissue in bones</p> Signup and view all the answers

Match the following layers of skin with their characteristics:

<p>Epidermis = Divided into five strata Dermis = Middle layer containing blood vessels Hypodermis = Connective layer storing fat Piloerection = A mechanism for heat retention</p> Signup and view all the answers

Match the following bone components with their roles:

<p>Calcitonin = Reduces blood calcium levels Parathyroid hormone = Increases blood calcium levels Osteoblasts = Stimulated to form new bone Osteoclasts = Break down bone during resorption</p> Signup and view all the answers

Match the following types of bone marrow with their functions:

<p>Red bone marrow = Responsible for hematopoiesis Yellow bone marrow = Stores fat Spongy bone = Contains red bone marrow Compact bone = Provides structural support</p> Signup and view all the answers

Match the following muscle types with their characteristics:

<p>Skeletal muscle = Voluntary control; striated fibers Smooth muscle = Involuntary control; non-striated fibers Cardiac muscle = Involuntary control; striated with intercalated discs Myogenic activity = Electrical activity independent of the brain</p> Signup and view all the answers

Match the following muscle proteins with their roles:

<p>Myosin = Thick filament component involved in contraction Actin = Thin filament component essential for contraction Troponin = Regulates interaction between actin and myosin Tropomyosin = Works with troponin to control muscle contraction</p> Signup and view all the answers

Match the following terms related to muscle contraction with their definitions:

<p>Sarcomere = Functional unit of a muscle fiber Contractile apparatus = Collection of proteins for muscle contraction Actin-myosin crossbridge cycle = 4-step process for muscle contraction Neuromuscular junction = Site of interaction between motor neurons and muscle fibers</p> Signup and view all the answers

Match the following components of the muscular system with their functions:

<p>Motor endplate = Contact point for motor neurons and muscle fibers Sarcoplasmic reticulum = Calcium ion storage for contraction regulation T-tubules = Facilitate signal propagation within muscle cells Motor neurons = Transmit signals from the nervous system to muscles</p> Signup and view all the answers

Match the following aspects of cardiac muscle with their features:

<p>Intercalated discs = Ensure coordinated contraction of heart muscle Purkinje fibers = Aids in contraction of cardiac muscle Cardiac muscle = Multinucleated and striated muscle found in the heart Myogenic activity = Regulates heart rhythm independent of the brain</p> Signup and view all the answers

Match the following terms related to muscle metabolism with their definitions:

<p>Oxygen debt = Result of oxygen deficiency during muscle exertion Contractile velocity = Speed of muscle fiber contraction ATP cleavage = Energy release mechanism during muscle contraction Sarcolemma = Cell membrane of a muscle cell</p> Signup and view all the answers

Match the following processes with their significance in muscle function:

<p>Calcium ion release = Trigger for muscle contraction Actin-myosin binding = Fundamental action in the contraction cycle Troponin-tropomyosin complex = Regulates actin-myosin interaction Skeletal muscle contraction = Enables voluntary movements</p> Signup and view all the answers

Match the following muscle contraction phases with their descriptions:

<p>Resting phase = Muscle not contracted; high calcium concentration in SR Excitation-contraction coupling = Linking neuronal signal to muscle contraction Contraction phase = Shortening of muscle fibers Relaxation phase = Return to resting state after contraction</p> Signup and view all the answers

Match the following concepts of muscle structure with their descriptions:

<p>Skeletal muscle tissue = Consciously controlled with striated appearance Smooth muscle tissue = Found in walls of internal organs and blood vessels Cardiac muscle tissue = Unique for its rhythmic contraction and endurance Sarcomere structure = Contains actin and myosin for contraction strength</p> Signup and view all the answers

Match the following germ layers with their corresponding derivatives:

<p>Endoderm = Epithelial lining of respiratory tract Mesoderm = Musculoskeletal system Ectoderm = Nervous system</p> Signup and view all the answers

Match the following organs with their developmental origin:

<p>Liver = Endoderm Pancreas = Endoderm Adrenal cortex = Mesoderm Gonads = Mesoderm</p> Signup and view all the answers

Match the following body systems with their corresponding germ layer:

<p>Circulatory system = Mesoderm Integumentary system (skin) = Ectoderm Nervous system = Ectoderm Linings of body cavities = Mesoderm</p> Signup and view all the answers

Match the following digestive structures with their origin:

<p>Stomach = Endoderm Epithelial lining of mouth = Ectoderm Epithelial lining of anus = Ectoderm Epithelial lining of respiratory tract = Endoderm</p> Signup and view all the answers

Match the following layers with their respective tissues:

<p>Ectoderm = Integumentary system (skin) Endoderm = Epithelial lining of digestive system Mesoderm = Circulatory system</p> Signup and view all the answers

Match the following embryonic layers with their corresponding derivatives:

<p>Endoderm = Lining of internal organs Mesoderm = Muscle and bone Ectoderm = Skin and nervous system Lateral plate mesoderm = Circulatory system and body cavities</p> Signup and view all the answers

Match the following embryonic structures with their functions:

<p>Notochord = Rod-like structure for support Neural tube = Develops into brain and spinal cord Somites = Differentiates into muscles and vertebrae Neural crest = Gives rise to various body tissues</p> Signup and view all the answers

Match the following development processes with their descriptions:

<p>Determination = Cell commits to specific cell type Differentiation = Cells change for specialized functions Gastrulation = Forms primary germ layers Organogenesis = Formation of organs</p> Signup and view all the answers

Match the following terms to their definitions:

<p>Apoptosis = Programmed cell death Morphogens = Signaling molecules for differentiation Inducer = Cell releasing morphogens Responder = Cell responding to morphogen signals</p> Signup and view all the answers

Match the following stages of embryonic development with their events:

<p>Gastrula = Inner cell mass differentiates Neurulation = Forms neural tube Blastopore = Opening of the archenteron Gestation = Period of pregnancy</p> Signup and view all the answers

Match the following embryonic terms with their meanings:

<p>Primitive streak = Establishes body's longitudinal axis Archenteron = Develops into gastrointestinal tract Deuterostomes = Blastopore develops into anus Parturition = Process of childbirth</p> Signup and view all the answers

Match the following embryonic processes with their significance:

<p>Morphogen signaling = Promotes tissue differentiation Apoptosis = Essential for tissue remodeling Neural folds = Elevations forming neural tube Somites formation = Structure for vertebral differentiation</p> Signup and view all the answers

Match the following cell types with their roles:

<p>Totipotent = Capable of all cell types Responder = Cell undergoing differentiation Inducer = Stimulates neighboring cells Morphogen = Promotes differentiation</p> Signup and view all the answers

Match the following terms with their corresponding structures:

<p>Amniotic sac = Surrounds embryo/fetus Endoderm = Innermost germ layer Ectoderm = Outermost germ layer Mesoderm = Middle germ layer</p> Signup and view all the answers

Match the following concepts in embryological development with their overview:

<p>Gastrulation = Formation of germ layers Neurulation = Nervous system development Organogenesis = Develops organs Apoptosis = Cell death in development</p> Signup and view all the answers

Match the following reproductive hormones with their source:

<p>GnRH = Hypothalamus FSH = Anterior pituitary gland LH = Anterior pituitary gland Testosterone = Leydig cells</p> Signup and view all the answers

Match the following stages of sperm development with their respective descriptions:

<p>Spermatogonium = Undifferentiated germ cell Primary spermatocyte = Diploid cell undergoing meiosis I Secondary spermatocyte = Haploid cell resulting from meiosis I Spermatids = Immature haploid cells maturing into spermatozoa</p> Signup and view all the answers

Match the following structures in the female reproductive system with their functions:

<p>Ovaries = Produce ova and hormones Fallopian tubes = Connect ovaries to uterus Zona pellucida = Protective layer around oocyte Granulosa cells = Form the zona pellucida</p> Signup and view all the answers

Match the following male reproductive structures with their functions:

<p>Testes = Sperm production and hormone secretion Vas deferens = Transports sperm to ejaculatory duct Seminiferous tubules = Site of spermatogenesis Acrosome = Enzyme release for egg penetration</p> Signup and view all the answers

Match the following phases in fertilization with their descriptions:

<p>Acrosomal reactions = Enzymes helping penetrate the zona pellucida Cortical reaction = Prevents polyspermy Zygote = Fertilized egg formation Blastulation = Morula develops into a blastocyst</p> Signup and view all the answers

Match the following types of cells with their roles in spermatogenesis:

<p>Sertoli cells = Support and nourish developing sperm Leydig cells = Produce testosterone Spermatogonium = Stem cell for sperm production Spermatids = Immature cells that mature into spermatozoa</p> Signup and view all the answers

Match the following ovarian cells with their functions:

<p>Theca cells = Produce estrogen Granulosa cells = Stimulated by FSH Oogonia = Undifferentiated germ cells Primary oocyte = Diploid cell undergoing meiosis I</p> Signup and view all the answers

Match the following terms related to early embryonic development with their meanings:

<p>Cleavage = Early cell divisions of the zygote Morula = Ball of packed cells Blastocyst = Structure formed after blastulation Inner cell mass = Develops into the embryo</p> Signup and view all the answers

Match the following definitions related to gamete formation with the correct term:

<p>Gametogenesis = Formation of sperm or ova Oogenesis = Process of oocyte production Spermatogenesis = Process of sperm formation Polyspermy = Egg fertilization by multiple sperm</p> Signup and view all the answers

Match the following types of feedback with their definitions:

<p>Negative feedback = A regulatory mechanism that counteracts changes to maintain stability Positive feedback = A process that amplifies the initial stimulus, leading to escalation</p> Signup and view all the answers

Match the following hormone types with their characteristics:

<p>Autocrine = Signaling that affects the secreting cell itself Paracrine = Signaling that affects nearby cells in the same tissue</p> Signup and view all the answers

Match the following cell types with their secretions:

<p>Islets of Langerhans = Produce insulin and glucagon Hypothalamus = Regulates pituitary gland functions by releasing hormones</p> Signup and view all the answers

Match the following glands with their types of secretion:

<p>Exocrine glands = Secrete substances outwardly through ducts Endocrine glands = Secrete hormones directly into the bloodstream</p> Signup and view all the answers

Match the following pancreatic functions with their roles:

<p>Insulin = Regulates blood sugar by facilitating glucose uptake Glucagon = Increases blood glucose levels by stimulating glycogen breakdown</p> Signup and view all the answers

Match the following hormones with their targets:

<p>FSH = Stimulates follicle development in ovaries TSH = Stimulates the thyroid gland to produce thyroid hormones</p> Signup and view all the answers

Match the following peptide characteristics with their descriptions:

<p>Peptide = Composed of two or more amino acids linked by peptide bonds Hormones = Chemical messengers produced by glands that cause specific responses</p> Signup and view all the answers

Match the following brain structures with their functions:

<p>Hypothalamus = Controls physiological functions and regulates the pituitary Pituitary gland = Releases hormones in response to signals from the hypothalamus</p> Signup and view all the answers

Match the following hormones with their specific effects:

<p>ACTH = Stimulates the adrenal cortex to release cortisol Prolactin = Stimulates milk production in mammary glands</p> Signup and view all the answers

Match the following hormones with their functions:

<p>Endorphins = Natural pain relief Oxytocin = Milk release stimulation ADH = Regulates water balance Calcitonin = Lowers blood calcium levels</p> Signup and view all the answers

Match the following hormones with their origins:

<p>hGH = Anterior pituitary gland hCG = Placenta T3 = Thyroid gland PTH = Parathyroid glands</p> Signup and view all the answers

Match the following adrenal structures with their secretions:

<p>Adrenal cortex = Cortisol Adrenal medulla = Epinephrine Aldosterone = Electrolyte regulation Norepinephrine = Stress response</p> Signup and view all the answers

Match the following hormonal axes with their functions:

<p>HPA = Stress response coordination HPG = Regulation of reproductive functions RAAS = Blood pressure regulation CRH or CRF = Stimulates ACTH release</p> Signup and view all the answers

Match the following thyroid hormones with their characteristics:

<p>T4 = Thyroxine T3 = More metabolically active Calcitonin = Bone-building stimulation PTH = Increases blood calcium levels</p> Signup and view all the answers

Match the following terms with their descriptions:

<p>Catecholamines = Tyrosine derivatives GHRH = Stimulates growth hormone release Epinephrine = Fight-or-flight hormone Cortisol = Glucocorticoid hormone</p> Signup and view all the answers

Match the following adrenal hormones with their types:

<p>Aldosterone = Mineralocorticoid Cortisol = Glucocorticoid Epinephrine = Catecholamine Norepinephrine = Catecholamine</p> Signup and view all the answers

Match the following hormones with their additional roles:

<p>Oxytocin = Uterine contractions ADH = Vasopressin hGH = Growth stimulation Endorphins = Stress response modulation</p> Signup and view all the answers

Match the following hormone interactions with their systems:

<p>HPA = Hypothalamic-pituitary-adrenal HPG = Hypothalamic-pituitary-gonadal RAAS = Renin-angiotensin-aldosterone CRH or CRF = Corticotropin-releasing factor</p> Signup and view all the answers

Match the following hormones with their physiological effects:

<p>Cortisol = Regulates metabolism Oxytocin = Facilitates childbirth PTH = Increases blood calcium Calcitonin = Stimulates bone formation</p> Signup and view all the answers

Match the following cells with their primary functions in the immune system:

<p>Neutrophils = First responders that phagocytose bacteria T cells = Execute the immune response against infected cells B cells = Produce antibodies in response to antigens Natural killer cells = Kill virus-infected or tumor cells</p> Signup and view all the answers

Match the following terms related to the immune system with their descriptions:

<p>Inflammation = Increased blood flow to an affected area Complement system = Signals to recruit phagocytes Opsonization = Tagging of pathogens for phagocytosis Cytokines = Signaling proteins that coordinate immune response</p> Signup and view all the answers

Match the following immune cell types with their characteristics:

<p>Monocytes = Differentiates into macrophages and dendritic cells Eosinophils = Targets parasitic infections Basophils = Involved in allergic responses Mast cells = Release histamine and found in mucous membranes</p> Signup and view all the answers

Match the following immune system responses with their descriptions:

<p>Primary immune response = First encounter with an antigen Secondary immune response = Faster reaction due to memory B cells Humoral immunity = Involves antibodies produced by B cells Cell-mediated immunity = Involves T cells executing the response</p> Signup and view all the answers

Match the following types of T cells with their functions:

<p>Helper T cells = Activate B cells and cytotoxic T cells Killer T cells = Destroy infected cells Memory T cells = Persist for rapid response upon re-encountering an antigen Regulatory T cells = Maintain immune tolerance and prevent autoimmunity</p> Signup and view all the answers

Match the following immune components with their roles:

<p>Immunoglobulins = Human antibodies with a Y-shaped configuration Variable region = Part of antibody that binds specific antigens Naïve B cells = B cells yet to encounter an antigen Clonal selection = Proliferation of immune cells in response to an antigen</p> Signup and view all the answers

Match the following terms related to T cell selection with their definitions:

<p>Positive selection = Eliminates T cells that cannot respond to antigens Negative selection = Eliminates T cells that respond too aggressively T cell receptor = Binds to specific antigens presented by MHC Major histocompatibility complex = Presents antigens to T cells for recognition</p> Signup and view all the answers

Match the following components of the innate immune system with their functions:

<p>Lysozyme = Breaks down bacterial cell walls Phagocyte = Engulfs and destroys pathogens Leukocytes = Primary cells of the immune system Lymphocytes = Type of white blood cell involved in adaptive immunity</p> Signup and view all the answers

Match the following terms with their corresponding concepts in immunology:

<p>Dendritic cells = Present antigens to T cells Macrophages = Engulf and digest pathogens Memory B cells = Remain dormant until re-encountering an antigen Helper T cells = Recruit and activate other immune cells</p> Signup and view all the answers

Match the following immune response terms with their definitions:

<p>Hematopoiesis = Production of blood cells in the bone marrow Antigen = Foreign particle recognized by antibodies White pulp = Lymphoid tissue in the spleen containing immune cells Clonal expansion = Proliferation of specific immune cells after activation</p> Signup and view all the answers

Match the parts of the nervous system with their descriptions:

<p>Central nervous system = Comprises the brain and spinal cord Peripheral nervous system = Connects the CNS to the rest of the body Autonomic nervous system = Controls involuntary bodily functions Somatic nervous system = Responsible for voluntary movements</p> Signup and view all the answers

Match the types of neurons with their functions:

<p>Dendrites = Receive signals from other neurons Axons = Transmit signals to other cells Ventral roots = Carry motor information Dorsal roots = Carry sensory information</p> Signup and view all the answers

Match the brain regions with their primary functions:

<p>Frontal lobe = Involved in executive functions Parietal lobe = Processes sensory information Occipital lobe = Responsible for visual processing Temporal lobe = Associated with auditory processing</p> Signup and view all the answers

Match the conditions with their related brain areas:

<p>Wernicke’s aphasia = Difficulty in understanding language Broca’s aphasia = Difficulty in producing speech Wernicke’s area = Associated with language comprehension Broca’s area = Involved in speech production</p> Signup and view all the answers

Match the parts of the brain with their specific roles:

<p>Corpus callosum = Connects the left and right hemispheres Cerebral cortex = Responsible for higher brain functions Ventral roots = Motor information to the body Dorsal roots = Sensory information to the spinal cord</p> Signup and view all the answers

Match the autonomic nervous system divisions with their responses:

<p>Parasympathetic nervous system = Rest and digest response Sympathetic nervous system = Fight-or-flight response Autonomic nervous system = Controls involuntary functions Somatic nervous system = Voluntary movement response</p> Signup and view all the answers

Match the parts of a neuron with their descriptions:

<p>Soma = The cell body of the neuron Dendrites = Branch-like extensions for receiving signals Axons = Long projections transmitting signals Myelin sheath = Insulation for faster signal transmission</p> Signup and view all the answers

Match the brain lobes with their functions:

<p>Frontal lobe = Reasoning and expressive language Parietal lobe = Spatial awareness and perception Occipital lobe = Visual processing Temporal lobe = Memory and language comprehension</p> Signup and view all the answers

Match the types of nervous systems with their characteristics:

<p>Peripheral nervous system = Nerves outside the CNS Autonomic nervous system = Involuntary control Somatic nervous system = Voluntary control Central nervous system = Brain and spinal cord</p> Signup and view all the answers

Match the following structures with their descriptions:

<p>Nodes of Ranvier = Gaps in the myelin sheath where action potentials are generated Saltatory conduction = The rapid transmission of action potentials in myelinated neurons Myelin = A fatty substance that insulates axons Synapse = The junction between two neurons where signals are transmitted</p> Signup and view all the answers

Match the types of neurons with their functions:

<p>Afferent neurons = Carry sensory information towards the central nervous system Efferent neurons = Carry motor information away from the central nervous system Interneurons = Connect afferent and efferent neurons Upper motor neuron = Originate from the brain and synapse onto lower motor neurons</p> Signup and view all the answers

Match the following processes with their definitions:

<p>Reuptake = Process of removing neurotransmitters from the synaptic cleft Enzymatic degradation = Breakdown of neurotransmitters by enzymes Synaptic pruning = Eliminating less active synapses Temporal summation = Combined effect of multiple signals arriving at a synapse rapidly</p> Signup and view all the answers

Match the following phases of action potential with their characteristics:

<p>Depolarization = Membrane potential decreases, inside becomes more positive Repolarization = Restoration of the membrane potential to its resting state Hyperpolarization = Membrane potential increases, inside becomes more negative Absolute refractory period = Neuron cannot generate another action potential</p> Signup and view all the answers

Match the components of the visual process with their roles:

<p>Photoreceptors = Respond to light and initiate visual process Cornea = Transparent outer layer of the eye Lens = Helps focus light onto the retina Optic nerve = Transmits visual information to the brain</p> Signup and view all the answers

Match the following nerve types with their functions:

<p>Monosynaptic reflex arc = Reflex arc with a single synapse Polysynaptic reflex arc = Involves multiple synapses between neurons Withdrawal reflex = Reflex action in response to a noxious stimulus Neuromuscular junction = Synapse between a motor neuron and muscle fiber</p> Signup and view all the answers

Match the following terms related to sound with their descriptions:

<p>Place theory = Explains how different locations in cochlea correspond to sound frequencies Somatosensation = Sensations related to touch, pressure, temperature, and pain Olfactory receptors = Detect odor molecules in the nasal cavity Olfactory bulb = Processes smell information from olfactory receptors</p> Signup and view all the answers

Match the following types of cell signaling with their descriptions:

<p>Spatial summation = Effect of signals from different synapses at the same time Saltatory conduction = Action potentials jump from node to node Synaptic plasticity = Ability of synapses to change over time Potassium and sodium leak channels = Allow passive movement of ions across the membrane</p> Signup and view all the answers

Match the following elements of the nervous system with their characteristics:

<p>Neuroglia = Support cells maintaining homeostasis Oligodendrocytes = Produce myelin in the central nervous system Schwann cells = Produce myelin in the peripheral nervous system Neurotransmitters = Chemical messengers between neurons</p> Signup and view all the answers

Match the following terms related to visual pigments with their components:

<p>Opsin = Protein component of photoreceptor cells Retinal = Light-sensitive molecule in photoreceptor cells Phototransduction = Conversion of light into electrical signals Ciliary muscle = Changes the shape of the lens for focusing</p> Signup and view all the answers

Study Notes

Mastication and Mechanical Digestion

  • Mastication is the chewing process that breaks food into smaller pieces to aid digestion.
  • Mechanical digestion involves physical breakdown through chewing, churning in the stomach, and muscle movements along the digestive tract.

Salivary Enzymes

  • Salivary amylase starts the breakdown of starches into simpler sugars like maltose.
  • Salivary lipase initiates fat digestion by breaking triglycerides into fatty acids and glycerol.

Food Processing and Passage

  • A bolus is a rounded mass of food formed after mixing with saliva, ready for swallowing.
  • The pharynx connects the nasal cavity and mouth to the esophagus and trachea.

Esophagus and Stomach Functions

  • The esophagus is a muscular tube transporting food to the stomach.
  • Peristalsis refers to wavelike contractions that propel food through the digestive tract.
  • The stomach mixes food with gastric juices, initiating protein digestion and controlling passage into the small intestine.

Stomach Cellular Functions

  • Parietal cells produce hydrochloric acid, creating an acidic environment.
  • Chief cells secrete pepsinogen, the precursor to pepsin, which breaks down proteins.
  • Gastrin is a hormone that stimulates gastric acid secretion.
  • Mucus protects and lubricates stomach tissues.

Chyme and Small Intestine Structure

  • Chyme is a semi-fluid mixture of partially digested food and gastric juices moving to the small intestine.
  • Microvilli are projections in the small intestine that increase surface area for absorption.

Nutrient Absorption

  • Fat-soluble vitamins (K, A, D, E) dissolve in fats and are stored in body tissues.
  • Lacteals absorb fats and fat-soluble vitamins into the lymphatic system.

Gut Microbiome and Waste Removal

  • Gut flora is a diverse community of microorganisms in the gastrointestinal tract aiding digestion and immune function.
  • The rectum stores feces prior to elimination, controlled by anal sphincters.

Enteric Nervous System

  • The enteric nervous system regulates gastrointestinal functions independently of the central nervous system.

Liver and Gallbladder Functions

  • The liver performs metabolic functions: bile production, detoxification, and nutrient storage.
  • Bile emulsifies fats for better digestion and absorption.
  • Albumin, a protein produced by the liver, transports substances in the bloodstream.
  • The gallbladder stores and concentrates bile.

Pancreas and Digestive Enzymes

  • The pancreas produces digestive enzymes and hormones like insulin and glucagon.
  • Brush-border enzymes on intestinal cells help break down complex molecules into absorbable nutrients.

Kidney Function and Structure

  • Nephrons filter, reabsorb, and secrete substances to form urine.
  • Filtration in the nephron forms urine from filtered blood.
  • Secretion involves transferring substances into the renal tubules for elimination.
  • Absorption reclaims useful substances into the bloodstream.

Nephron Anatomy

  • Bowman’s capsule surrounds the glomerulus, collecting filtered fluid.
  • The glomerulus is a network of tiny blood vessels for filtration.
  • Starling’s forces regulate fluid movement across capillary walls in the kidney.

Renal Tubule Segments

  • The proximal convoluted tubule reabsorbs water, ions, and nutrients.
  • Loop of Henle facilitates additional water and ion reabsorption; has descending (water permeable) and ascending (ion permeable) limbs.
  • Distal convoluted tubule fine-tunes electrolyte balance and water reabsorption via hormones.
  • The collecting duct further concentrates urine.

Kidney Regions and Hormonal Regulation

  • The medulla contains renal pyramids and loops of Henle; the cortex houses glomeruli and convoluted tubules.
  • The renal capsule protects the kidney.
  • Aldosterone regulates sodium and potassium levels; renin helps control blood pressure.
  • Antidiuretic hormone (ADH) regulates water reabsorption in the kidneys.

Osmoregulation

  • Osmoregulation maintains fluid and ion balance for internal stability and cell function.

Gel Electrophoresis

  • A technique for separating mixture components based on size and charge.
  • Utilizes a gel matrix, commonly made of polyacrylamide (PAGE), as the medium.

Electric Charges

  • The cathode is the negatively charged side, attracting positive ions.
  • The anode is the positively charged side, attracting negative ions.

Types of Gel Electrophoresis

  • SDS-PAGE: Involves sodium dodecyl sulfate to denature proteins and impart uniform negative charge.
  • Reducing SDS-PAGE: Similar to SDS-PAGE but includes a reducing agent to break disulfide bonds.
  • Native-PAGE: Preserves protein structure, allowing examination of native forms without denaturation.
  • Isoelectric Focusing: Separates proteins based on their isoelectric point (pI), where they have no net charge.

Blotting Techniques

  • Northern Blot: Identifies specific RNA strands post-gel electrophoresis.
  • Southern Blot: Identifies specific DNA strands post-gel electrophoresis.
  • Western Blot: Identifies specific proteins post-gel electrophoresis.

Antibody Techniques

  • Primary Antibody: The initial antibody that binds to a target protein.
  • Secondary Antibody: Conjugated with a label (fluorescent/enzyme) to facilitate detection of the primary antibody.

Molecular Techniques

  • Sanger Method: Sequencing technique for determining DNA sequences.
  • Primer: Short DNA/RNA strand essential for initiating DNA replication.
  • Reverse Transcriptase: Enzyme that synthesizes DNA from an RNA template.
  • Polymerase Chain Reaction (PCR): Amplifies specific DNA sequences to generate numerous copies.
  • cDNA Library: Contains genes of interest stored in host cells, typically bacteria.

Enzyme-Linked Immunosorbent Assays (ELISA)

  • Indirect ELISA: Detects antibody binding by using a secondary, reporter-linked antibody.
  • Direct ELISA: Uses reporter-linked primary antibody for direct observation of binding.
  • Sandwich ELISA: Measures antigen concentration by sequential addition of immobilized antibody, antigen, and labeled antibody.

Genetic Manipulation Techniques

  • Bacterial Transformation: Bacteria uptake genetic material from the environment.
  • Plasmids: Circular DNA molecules used as vectors in genetic engineering.
  • Restriction Enzymes/Endonucleases: Enzymes that cut DNA at specific sequences.

Separation Techniques

  • Centrifugation: Separates components by spinning; creates pellet (dense substances) and supernatant (less dense substances).
  • Chromatography: Isolates a substance from a mixture based on interactions with stationary and mobile phases.
    • Mobile Phase: Liquid carrying the substance of interest.
    • Stationary Phase: Immobilized medium that interacts with the substance.
    • Gel Filtration (Size Exclusion) Chromatography: Separates based on size using porous beads.
    • Ion-Exchange Chromatography: Separates by charge using charged stationary phases.
      • Anion-Exchange: Attracts negatively charged molecules.
      • Cation-Exchange: Attracts positively charged molecules.
    • Affinity Chromatography: Isolates targets using a stationary phase with a specific affinity for the substance.

Elution

  • The process of detaching a substance of interest from the stationary phase to allow it to exit the chromatography column.

Muscle Tissue

  • Skeletal muscle enables voluntary movement and is innervated by the somatic nervous system.
  • Smooth muscle operates involuntarily, controlled by the autonomic nervous system.
  • Cardiac muscle, located in the heart, contains intercalated discs for coordinated contractions.

Muscle Contraction

  • Contractile velocity refers to the speed at which muscle fibers contract.
  • The actin-myosin crossbridge cycle involves ATP cleavage and binding, leading to muscle contraction.
  • Myosin forms thick filaments, while actin forms thin filaments, both vital to the crossbridge cycle.
  • Troponin and tropomyosin regulate muscle contraction by controlling the interaction between actin and myosin.

Muscle Physiology

  • Oxygen debt occurs when the oxygen demand by muscles exceeds supply during energy production.
  • Sarcoplasmic reticulum stores Ca2+ ions essential for muscle contraction and is integral to the sarcomere structure.
  • The power stroke is the movement of myosin heads, shortening the sarcomere as ADP and inorganic phosphate are released.
  • Shivering generates heat through small muscle contractions, aiding in thermoregulation.

Bone Structure and Function

  • Bones are categorized into spongy and compact varieties; spongy bone contains red bone marrow for hematopoiesis.
  • Osteons are the basic units of compact bone, featuring Haversian canals for blood vessel housing.
  • Osteoblasts form bone, while osteoclasts resorb bone matrix; their activities are regulated by calcitonin and parathyroid hormone (PTH).

Ossification

  • Intramembranous ossification occurs within fibrous membranes, forming flat bones.
  • Endochondral ossification involves cartilage models replaced by bone tissue, primarily in long bones.

Connective Tissues

  • Tendons attach muscles to bones; ligaments connect bones to other bones.
  • Both tendons and ligaments are composed of strong, flexible collagen.

Skin Layers

  • The epidermis is the outermost skin layer, composed of five strata.
  • The dermis contains essential structures such as sweat glands, hair follicles, blood vessels, and sensory nerve endings.
  • The hypodermis anchors skin to underlying muscles and stores adipose tissue.

Thermoregulation Mechanisms

  • Piloerection raises hair to trap heat, aiding in temperature regulation.
  • Evaporative cooling dissipates heat through sweat evaporation.
  • Vasodilation increases blood vessel diameter, enhancing heat transfer to the skin's surface for cooling.

Endoderm

  • Forms the epithelial lining of the digestive system, playing a crucial role in digestion and nutrient absorption.
  • Represents the epithelial lining of the respiratory tract, essential for gas exchange and respiratory function.
  • Contributes to the development of vital organs, including the liver, which aids in metabolic processes and detoxification.
  • Involved in the formation of the pancreas, an organ crucial for digestion and blood sugar regulation.
  • Responsible for the development of the stomach, which is integral to food storage and digestion.

Mesoderm

  • Gives rise to the musculoskeletal system, providing structure and support for body movement.
  • Forms the circulatory system, including the heart and blood vessels, facilitating transport of nutrients and oxygen.
  • Develops the gonads, which are necessary for reproduction and hormone production.
  • Creates linings of body cavities, ensuring protection and separation of internal organs.
  • Forms the adrenal cortex, which is vital for hormone production related to stress and metabolism.

Ectoderm

  • Leads to the formation of the integumentary system, which includes the skin, hair, and nails, protecting the body from the environment.
  • Responsible for the development of the nervous system, controlling bodily functions and responses to stimuli.
  • Contributes to the epithelial lining of the mouth and anus, maintaining important roles in digestion and waste elimination.

HPG Axis and Hormones

  • The hypothalamus, anterior pituitary gland, and gonads form the HPG axis, crucial for endocrine control.
  • GnRH (gonadotropin-releasing hormone) is released by the hypothalamus, stimulating the anterior pituitary.
  • FSH (follicle-stimulating hormone) and LH (luteinizing hormone) are produced by the anterior pituitary and play key roles in regulating gametogenesis.

Male Reproductive System

  • Testes: Male reproductive glands responsible for sperm production and hormone secretion.
  • Spermatogenesis occurs in seminiferous tubules and involves spermatogonia, primary spermatocytes, secondary spermatocytes, spermatids, and spermatozoa.
  • Sertoli cells support and nourish developing sperm and are stimulated by FSH.
  • Leydig cells produce testosterone in response to LH stimulation.

Sperm Structure and Function

  • Spermatozoa are mature male reproductive cells, capable of fertilizing an egg.
  • The acrosome contains enzymes to penetrate the egg, while the flagellum provides motility.
  • The vas deferens transports sperm to the ejaculatory duct.

Female Reproductive System

  • Ovaries: Female reproductive organs responsible for ova production and hormone secretion.
  • Oogenesis involves oogonia developing into primary oocytes and secondary oocytes, which can be fertilized.
  • Polar bodies are discarded cells from meiotic divisions that do not contribute to reproduction.

Fertilization and Early Development

  • Fertilization occurs when a sperm cell merges with an ovum, forming a zygote.
  • Acrosomal reactions allow sperm to penetrate the zona pellucida, while cortical reactions prevent polyspermy.
  • Zygote undergoes cleavage, forming a multicellular organism, and becomes an embryo by the end of eight weeks.

Stages of Development

  • Morula: A ball of tightly packed cells formed from the zygote.
  • Blastocyst: Structure with a blastocoel, inner cell mass (ICM), and trophoblast; leads to implantation.
  • Pluripotent cells can develop into various body cell types, while totipotent cells can give rise to all cell types, including extraembryonic tissues.

Gastrulation and Germ Layers

  • Gastrulation forms three germ layers: endoderm, mesoderm, and ectoderm.
  • The primitive streak establishes the body's axis; the archenteron will become the gastrointestinal tract.
  • Endoderm forms internal organ linings, mesoderm yields muscles and bones, and ectoderm creates skin and nervous system structures.

Neurulation and Organ Development

  • Notochord forms in the mesoderm and contributes to vertebral column development.
  • Neural folds create the neural tube, which develops into the brain and spinal cord.
  • Neural crest cells migrate from the neural tube, forming various body tissues.

Additional Developmental Processes

  • Gestation refers to the pregnancy period; organogenesis is the development of organs.
  • Parturition is the childbirth process; the amniotic sac surrounds the embryo for protection.
  • Determination and differentiation define a cell's commitment to its specific type and function.
  • Morphogens influence differentiation; inducers release morphogens, while responders undergo differentiation.
  • Apoptosis is programmed cell death vital for tissue remodeling during development.

Regulatory Mechanisms

  • Negative Feedback: A process where the output of a system counteracts changes, maintaining stability or homeostasis.
  • Positive Feedback: A regulatory mechanism in which output amplifies the initial stimulus, potentially leading to an escalation away from the original state.

Hormonal Signaling

  • Hormones: Chemical messengers produced by glands that circulate in the bloodstream to target cells, eliciting specific biological responses.
  • Autocrine Signaling: A cell secretes signaling molecules that bind to its own receptors or those of similar neighboring cells.
  • Paracrine Signaling: Cells release signaling molecules that affect nearby cells, facilitating communication within the same tissue.

Types of Bioactive Compounds

  • Peptides: Compounds made of two or more amino acids linked by peptide bonds; include peptide hormones, typically short proteins.
  • GPCR: G-protein coupled receptors, family of cell surface receptors important in many signaling pathways.

Cholesterol and Gland Functions

  • Cholesterol: A lipid crucial for building cell membranes and serves as a precursor for steroid hormones.
  • Exocrine Glands: Secrete substances outward through ducts (e.g., sweat glands).
  • Endocrine Glands: Release hormones directly into the bloodstream, affecting distant target tissues.

Pancreas and Hormonal Roles

  • Pancreas: Functions as both an endocrine and exocrine organ, producing insulin and digestive enzymes.
  • Islets of Langerhans: Clusters of cells in the pancreas, including α, β, and δ cells, responsible for producing insulin, glucagon, and somatostatin.
  • Insulin: Regulates blood sugar by facilitating glucose uptake into cells.
  • Glucagon: Increases blood glucose levels by stimulating glycogen breakdown in the liver.
  • Somatostatin: Inhibits the release of hormones including insulin and glucagon.

Brain and Pituitary Regulation

  • Hypothalamus: Brain region controlling physiological functions and regulating the pituitary gland's activity via hormone release.
  • Hypophyseal Portal System: Blood vessels connecting hypothalamus and anterior pituitary, allowing direct communication.
  • Relevant Hormones:
    • FSH: Follicle-stimulating hormone.
    • LH: Luteinizing hormone.
    • ACTH: Adrenocorticotropic hormone.
    • TSH: Thyroid-stimulating hormone.
    • Prolactin: Stimulates milk production in mammary glands.
    • Endorphins: Natural painkillers released in response to stress or pain.

Growth and Reproductive Hormones

  • GHRH: Growth hormone-releasing hormone.
  • hGH: Human growth hormone.
  • hCG: Human chorionic gonadotropin.
  • Oxytocin: Stimulates milk release and aids uterine contractions during childbirth.
  • ADH: Antidiuretic hormone, also known as vasopressin.

Thyroid and Parathyroid Hormones

  • T3 and T4: Triiodothyronine and thyroxine, hormones that regulate metabolism.
  • Calcitonin: Promotes bone formation and reduces blood calcium levels.
  • Parathyroid Hormone (PTH): Increases blood calcium levels.

Adrenal Hormones

  • Adrenal Cortex: Outer layer producing cortisol and aldosterone, vital for metabolism and blood pressure regulation.
  • Adrenal Medulla: Inner part producing epinephrine and norepinephrine, involved in the "fight-or-flight" response.
  • Aldosterone: Regulates electrolyte balance and blood pressure.
  • Cortisol: Regulates metabolism and immune response.
  • Epinephrine and Norepinephrine: Catecholamines involved in stress response and neurotransmission.
  • Catecholamines: Derivatives of tyrosine, including epinephrine and norepinephrine.

Regulatory Axes and Systems

  • HPA Axis: Hypothalamic-pituitary-adrenal axis, regulating stress response.
  • HPG Axis: Hypothalamic-pituitary-gonadal axis, pivotal for reproductive functions.
  • RAAS: Renin-angiotensin-aldosterone system, regulating blood pressure and fluid balance.
  • CRH (CRF): Corticotropin-releasing hormone/factor, involved in the stress response.

Innate Immune System

  • Provides general protection against diseases without recognizing specific pathogens.
  • Lysozyme is a protein in saliva that breaks down bacterial cell walls.

Leukocytes (White Blood Cells)

  • Primary cells of the immune system; crucial for defense.
  • Neutrophils are the most abundant white blood cells, first responders that phagocytize bacteria.
  • Lymphocytes are the second most common and include natural killer cells that target virus- and tumor-infected cells.

Monocytes and their Derivatives

  • Monocytes can differentiate into macrophages (large phagocytic cells) and dendritic cells (antigen presenters).
  • Eosinophils target parasitic infections, while basophils trigger allergic responses by releasing histamine.
  • Mast cells, similar to basophils, are found mainly in mucous membranes and connective tissues.

Phagocytosis and Immune Signaling

  • Phagocytes engulf and destroy pathogens through phagocytosis.
  • The complement system tags pathogens with proteins, promoting phagocyte recruitment.
  • Opsonization refers to proteins attaching to pathogens for easier recognition by phagocytes.

Cytokines and Inflammation

  • Cytokines are signaling proteins that coordinate immune responses.
  • Inflammation occurs in response to injury or pathogens, increasing blood flow and immune cell availability.

Adaptive Immune System

  • Features the ability to adapt and learn to recognize specific pathogens.
  • Naïve B cells are unexposed to antigens, while plasma cells are activated B cells producing antibodies.
  • Memory B cells remain dormant until re-exposure to the same antigen, allowing for a quicker response.

Immune Response Dynamics

  • The primary immune response is slower as naïve B cells encounter antigens for the first time.
  • The secondary immune response is expedited due to the presence of memory B cells.

Immune System Properties

  • Humoral immunity involves B cells and antibody production, while cell-mediated immunity involves T cells.
  • Positive selection ensures T cells accurately respond to antigens, while negative selection eliminates overly aggressive T cells to prevent autoimmunity.

T Cell Types and Functions

  • Helper T cells (CD4+) activate other immune cells by binding to MHC class II proteins.
  • Killer T cells (CD8+) destroy infected cells by identifying presented antigens through MHC class I.

Antigen Recognition

  • Major histocompatibility complex (MHC) proteins present antigens on cell surfaces; MHC class I is found in all cells, while MHC class II is specific to immune cells.
  • Antigen-presenting cells, such as macrophages and dendritic cells, display antigens to activate T cells.

Blood Cell Formation and Types

  • Hematopoiesis is the process of blood cell production in the bone marrow.
  • Erythrocytes are red blood cells responsible for oxygen transport.

Antibodies (Immunoglobulins)

  • Five classes of antibodies with a Y-shaped structure; they recognize specific antigens through their variable regions.
  • The constant region influences the antibody class and stabilizes its structure.

Epitopes and Paratopes

  • Epitopes are specific regions on antigens that antibodies recognize.
  • Paratopes are regions on antibodies that bind to antigens, diverging through random recombination to enable diverse antibody formation.

Autoimmune Disorders

  • Occur when immune cells mistakenly attack healthy body cells, examples include lupus, multiple sclerosis, and rheumatoid arthritis.

Central Nervous System (CNS)

  • Comprises the brain and spinal cord, responsible for processing and transmitting information to and from the body.

Peripheral Nervous System (PNS)

  • Consists of nerves and ganglia outside the CNS, connecting it to the rest of the body supporting sensorimotor functions.

Spinal Nerve Roots

  • Dorsal Roots: Carry sensory information from the body to the spinal cord.
  • Ventral Roots: Exit the spinal cord carrying motor information to the body.

Brain Anatomy

  • Cerebral Cortex: Outer layer of the cerebrum, involved in higher brain functions like thinking and memory.
  • Frontal Lobe: Responsible for executive functions, reasoning, motor skills, and expressive language.
  • Parietal Lobe: Processes sensory information, spatial awareness, and perception.
  • Occipital Lobe: Mainly processes visual information.
  • Temporal Lobe: Associated with auditory processing, memory, and language comprehension.

Brain Regions

  • Corpus Callosum: Connects the left and right hemispheres, facilitating interhemispheric communication.
  • Wernicke’s Area: Involved in language comprehension; damage leads to Wernicke’s aphasia, impairing understanding of language.
  • Broca’s Area: Involved in speech production; damage results in Broca’s aphasia, leading to difficulty in speech coherence.

Nervous System Divisions

  • Autonomic Nervous System: Controls involuntary bodily functions (e.g., heartbeat).
    • Parasympathetic Nervous System: Promotes rest and digestion.
    • Sympathetic Nervous System: Triggers fight-or-flight responses.
  • Somatic Nervous System: Governs voluntary movements and sensory information.

Neuron Structure and Function

  • Soma: Neuron's cell body housing the nucleus.
  • Dendrites: Receive signals from other neurons.
  • Axons: Transmit signals to other cells.
  • Action Potential: Electrical signal propagating along a neuron's membrane during impulse transmission.

Neural Support Cells

  • Oligodendrocytes: Produce myelin in the CNS.
  • Schwann Cells: Produce myelin in the PNS.
  • Myelin: Fatty substance that insulates axons, increasing transmission speed.
  • Nodes of Ranvier: Gaps in myelin for action potential generation.

Signal Transmission

  • Saltatory Conduction: Rapid transmission of action potentials in myelinated neurons node-to-node.
  • Synapse: Junction between two neurons for signal transmission via neurotransmitters.
  • Synaptic Plasticity: Synapses adapt over time based on activity.
  • Synaptic Pruning: Eliminating less active synapses to refine neural connections.

Ion Channels and Membrane Potential

  • Potassium and Sodium Leak Channels: Allow ion movement across the membrane.
  • Sodium-Potassium Pump: Maintains resting potential; pumps sodium out and potassium in.
  • Hyperpolarization: Increases negative membrane potential.
  • Depolarization: Decreases negative membrane potential, making it more positive.
  • Repolarization: Restores membrane potential after depolarization.

Refractory Periods

  • Absolute Refractory Period: No action potential possible regardless of stimulus strength.
  • Relative Refractory Period: Action potential possible only with a stronger-than-usual stimulus.

Neurotransmitters and Synaptic Mechanisms

  • Neurotransmitters: Chemical messengers transmitting signals between neurons.
  • Temporal Summation: Multiple signals arriving quickly at a synapse.
  • Spatial Summation: Signals from different synapses converging simultaneously.
  • Reuptake: Removal of neurotransmitters from the synaptic cleft by the presynaptic neuron.
  • Enzymatic Degradation: Breakdown of neurotransmitters by enzymes.

Neuron Types

  • Afferent Neurons: Carry sensory information to the CNS.
  • Efferent Neurons: Carry motor information away from the CNS.
  • Interneurons: Connect afferent and efferent neurons for communication.

Reflex Arcs

  • Withdrawal Reflex: Reflexive response to noxious stimuli, causing withdrawal.
  • Polysynaptic Reflex Arc: Involves multiple synapses between afferent and efferent neurons.
  • Monosynaptic Reflex Arc: Consists of a single synapse between afferent and efferent neurons.

Motor Control

  • Upper Motor Neurons: Originate from the brain and synapse with lower motor neurons in the spinal cord.
  • Lower Motor Neurons: Innervate muscles via neuromuscular junctions.
  • Neuromuscular Junction: Synapse between a motor neuron and a muscle fiber.

Visual System

  • Photoreceptors: Retina cells that respond to light.
  • Cornea: Transparent outer layer covering the eye.
  • Pupil: Regulates light entering the eye.
  • Lens: Focuses light onto the retina.
  • Retina: Contains photoreceptors and is sensitive to light.
  • Ciliary Muscle: Changes lens shape for focusing.

Optics and Perception

  • Optic Nerve: Transmits visual information from the eye to the brain.
  • Optic Nerve Chiasm: Point where optic nerves partially cross, sharing signals between both brain hemispheres.

Chemical and Sensory Detection

  • Retinal: Light-sensitive molecule in photoreceptors.
  • Opsin: Protein that combines with retinal to form visual pigments.
  • Phototransduction: Conversion of light into electrical signals in photoreceptors.

Auditory Processing

  • Place Theory: Explains frequency sound perception based on cochlea location.
  • Somatosensation: Includes touch, pressure, temperature, and pain sensations.

Olfactory System

  • Olfactory Receptors: Detect odor molecules in the nasal cavity.
  • Olfactory Bulb: Processes smell information from olfactory receptors.

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This quiz covers the essential aspects of human digestion, including the processes of mastication, mechanical digestion, and the role of salivary enzymes. It also explores the function of the esophagus and stomach in food processing and passage. Test your knowledge on how food is broken down and transported through the digestive system.

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