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Questions and Answers
What is one of the primary roles of the central nervous system?
What is one of the primary roles of the central nervous system?
Which statement accurately describes the function of the blood-brain barrier?
Which statement accurately describes the function of the blood-brain barrier?
What are the two divisions of the autonomic nervous system?
What are the two divisions of the autonomic nervous system?
Which of the following structures has a primary role in sensory input?
Which of the following structures has a primary role in sensory input?
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What is one of the functions of the meninges?
What is one of the functions of the meninges?
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What role does the myelin sheath play in nerve impulse transmission?
What role does the myelin sheath play in nerve impulse transmission?
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Which neurotransmitter is associated with the parasympathetic division?
Which neurotransmitter is associated with the parasympathetic division?
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What happens during the repolarization phase of an action potential?
What happens during the repolarization phase of an action potential?
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How does a local anaesthetic affect nerve impulses?
How does a local anaesthetic affect nerve impulses?
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What mechanism is responsible for restoring the resting membrane potential after an action potential?
What mechanism is responsible for restoring the resting membrane potential after an action potential?
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What is the primary function of motor output in the nervous system?
What is the primary function of motor output in the nervous system?
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What role do descending tracts play in the spinal cord?
What role do descending tracts play in the spinal cord?
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Which lobe of the brain is primarily responsible for personality and decision-making?
Which lobe of the brain is primarily responsible for personality and decision-making?
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Which lobe is the principal center for receiving and interpreting sensations such as touch and pain?
Which lobe is the principal center for receiving and interpreting sensations such as touch and pain?
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Which part of the brain is primarily concerned with processing visual information?
Which part of the brain is primarily concerned with processing visual information?
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What type of division is the autonomic nervous system classified as?
What type of division is the autonomic nervous system classified as?
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What is the largest part of the human brain?
What is the largest part of the human brain?
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Which of the following sensations is primarily governed by the temporal lobe?
Which of the following sensations is primarily governed by the temporal lobe?
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What is the primary function of the basal ganglia?
What is the primary function of the basal ganglia?
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Which condition is primarily associated with dysfunction of the basal ganglia?
Which condition is primarily associated with dysfunction of the basal ganglia?
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What is the most common cause of cerebellar dysfunction?
What is the most common cause of cerebellar dysfunction?
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What functions does the cerebellum contribute to in humans?
What functions does the cerebellum contribute to in humans?
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What is the role of the thalamus in the brain?
What is the role of the thalamus in the brain?
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What is the composition of the brainstem?
What is the composition of the brainstem?
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What external factors can the blood-brain barrier effectively exclude?
What external factors can the blood-brain barrier effectively exclude?
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What kind of issues would be expected in a patient with trauma to the pons?
What kind of issues would be expected in a patient with trauma to the pons?
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What role do receptors play in neurotransmission?
What role do receptors play in neurotransmission?
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Which of the following neurotransmitters are associated with the sympathetic nervous system?
Which of the following neurotransmitters are associated with the sympathetic nervous system?
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What is the main function of the parasympathetic nervous system?
What is the main function of the parasympathetic nervous system?
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How does the sympathetic nervous system primarily affect physiological responses?
How does the sympathetic nervous system primarily affect physiological responses?
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What structure is involved in the release of neurotransmitters during synaptic transmission?
What structure is involved in the release of neurotransmitters during synaptic transmission?
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Which component acts as the initial site for transmitting nerve impulses?
Which component acts as the initial site for transmitting nerve impulses?
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What effect does the activation of adrenergic receptors have on the body?
What effect does the activation of adrenergic receptors have on the body?
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What is the primary function of neurotransmitters once they are released into the synaptic cleft?
What is the primary function of neurotransmitters once they are released into the synaptic cleft?
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What characterizes a reflex arc?
What characterizes a reflex arc?
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Which condition is characterized by the destruction of nervous tissue without regeneration?
Which condition is characterized by the destruction of nervous tissue without regeneration?
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What is the primary consequence of a cerebrovascular accident (CVA)?
What is the primary consequence of a cerebrovascular accident (CVA)?
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Which of the following is NOT a characteristic of Alzheimer’s disease?
Which of the following is NOT a characteristic of Alzheimer’s disease?
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Which type of nociceptor responds to fast pain, such as a needle puncture?
Which type of nociceptor responds to fast pain, such as a needle puncture?
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What defines visceral sensation?
What defines visceral sensation?
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Which of the following statements about pain is incorrect?
Which of the following statements about pain is incorrect?
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Which classification of sensations includes taste and hearing?
Which classification of sensations includes taste and hearing?
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What is the primary role of the nervous system in maintaining balance within other systems?
What is the primary role of the nervous system in maintaining balance within other systems?
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Which structure primarily separates the brain from potentially harmful substances in the blood?
Which structure primarily separates the brain from potentially harmful substances in the blood?
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Which division of the nervous system is responsible for sensory input and integrating that information?
Which division of the nervous system is responsible for sensory input and integrating that information?
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What function is primarily impaired in individuals with disorders of the nervous system?
What function is primarily impaired in individuals with disorders of the nervous system?
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What role do meninges play in the nervous system?
What role do meninges play in the nervous system?
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What process occurs immediately after depolarization during an action potential?
What process occurs immediately after depolarization during an action potential?
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Which of the following is a result of the sodium-potassium pump's action?
Which of the following is a result of the sodium-potassium pump's action?
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How does the presence of a myelin sheath influence nerve impulse transmission?
How does the presence of a myelin sheath influence nerve impulse transmission?
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In multiple sclerosis, which aspect of nerve function is primarily affected?
In multiple sclerosis, which aspect of nerve function is primarily affected?
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What initiates an action potential in a neuron?
What initiates an action potential in a neuron?
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Damage to which brain structure primarily results in loss of fine motor control?
Damage to which brain structure primarily results in loss of fine motor control?
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Which brain region acts as a relay station for all sensory stimuli?
Which brain region acts as a relay station for all sensory stimuli?
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What type of breathing problems are likely to arise from trauma to the pons?
What type of breathing problems are likely to arise from trauma to the pons?
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Which of the following is a consequence of alcohol poisoning on the cerebellum?
Which of the following is a consequence of alcohol poisoning on the cerebellum?
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What does the cerebrospinal fluid NOT provide for the brain?
What does the cerebrospinal fluid NOT provide for the brain?
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In addition to sensory exclusion, what else does the blood-brain barrier do?
In addition to sensory exclusion, what else does the blood-brain barrier do?
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Which of the following neurologic conditions is closely related to basal ganglia dysfunction?
Which of the following neurologic conditions is closely related to basal ganglia dysfunction?
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What is the primary role of the sensory (afferent) division of the peripheral nervous system?
What is the primary role of the sensory (afferent) division of the peripheral nervous system?
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Which lobe of the brain is primarily involved in processing sensory input such as touch and temperature?
Which lobe of the brain is primarily involved in processing sensory input such as touch and temperature?
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Which statement accurately describes the function of descending tracts in the spinal cord?
Which statement accurately describes the function of descending tracts in the spinal cord?
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What function is primarily associated with the temporal lobe of the brain?
What function is primarily associated with the temporal lobe of the brain?
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What occurs at the synapse when an electrical impulse reaches a neuron?
What occurs at the synapse when an electrical impulse reaches a neuron?
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The autonomic nervous system is classified as which type of division?
The autonomic nervous system is classified as which type of division?
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The spinal cord functions primarily to:
The spinal cord functions primarily to:
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Which neurotransmitters are primarily involved in the sympathetic nervous system?
Which neurotransmitters are primarily involved in the sympathetic nervous system?
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Which division of the autonomic nervous system is associated with a relaxed state?
Which division of the autonomic nervous system is associated with a relaxed state?
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Which of the following best describes the functions of the cerebrum?
Which of the following best describes the functions of the cerebrum?
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What happens to the digestive system when the sympathetic nervous system is activated?
What happens to the digestive system when the sympathetic nervous system is activated?
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Activation of which lobe would most likely impair the ability to recognize visual stimuli?
Activation of which lobe would most likely impair the ability to recognize visual stimuli?
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Where does the binding of neurotransmitters occur in synaptic transmission?
Where does the binding of neurotransmitters occur in synaptic transmission?
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What role do mitochondria play in the synapse?
What role do mitochondria play in the synapse?
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What physiological changes are primarily associated with the 'fight or flight' response?
What physiological changes are primarily associated with the 'fight or flight' response?
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What is the primary function of the synaptic cleft?
What is the primary function of the synaptic cleft?
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What is the primary characteristic of a concussion?
What is the primary characteristic of a concussion?
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Which of the following best describes cerebral edema?
Which of the following best describes cerebral edema?
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What type of receptors are nociceptors?
What type of receptors are nociceptors?
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What is a significant consequence of a cerebrovascular accident (CVA)?
What is a significant consequence of a cerebrovascular accident (CVA)?
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Which factor characterizes slow pain transmitted through C nerve fibers?
Which factor characterizes slow pain transmitted through C nerve fibers?
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Which statement about Alzheimer’s disease is correct?
Which statement about Alzheimer’s disease is correct?
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Which of the following is NOT a general sensation classification?
Which of the following is NOT a general sensation classification?
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What role does pain serve in human physiology?
What role does pain serve in human physiology?
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Study Notes
Introduction to the Nervous System
- The nervous system is a highly complex system divided into two major parts:
- Central nervous system (CNS)
- Peripheral nervous system
- The nervous system controls all other organ systems and is essential for maintaining balance within those systems.
- Nervous system disorders are numerous and often difficult to diagnose and treat.
Objectives
- Explain the difference between the central and peripheral nervous systems.
- Describe the functions of the nervous system.
- Describe the structure of a neuron.
- Describe the structure and function of a synapse.
- Describe the function of the blood-brain barrier.
- Describe functions of meninges.
- Describe the functions of the spinal cord.
- List the major divisions of the brain and give the general functions of each.
- Explain the two divisions of the autonomic nervous system.
Organization of the Nervous System
- The nervous system is divided into the central nervous system (CNS) and the peripheral nervous system (PNS).
- The CNS consists of the brain and spinal cord.
- The PNS consists of nerves that carry sensory and motor information between the CNS and the rest of the body.
- Afferent (sensory) division
- Efferent (motor) division
- somatic nervous system
- autonomic nervous system
Functions of the Nervous System
- Sensory input: gathering information; monitoring changes inside and outside the body.
- Integration: processing and interpreting sensory input and deciding if action is needed.
- Motor output: a response to integrated stimuli activates muscles or glands.
Functional Classification of the Peripheral Nervous System
- Sensory (afferent) division: carries information to the CNS.
- Motor (efferent) division: carries impulses away from the CNS.
- Somatic: voluntary nervous system
- Autonomic: involuntary nervous system
Spinal Cord - Ascending and Descending Tracts
- The spinal cord carries information to and from the brain.
- Ascending tracts carry sensory information up to the brain.
- Descending tracts carry motor information down from the brain to muscles and glands.
Apply Your Knowledge - Answer
- Descending tracts carry motor information down from the brain to muscles and glands.
The Brain
- Four parts:
- Cerebrum
- Diencephalons
- Brain stem
- Cerebellum
Functions of the Cerebrum
- The largest part of the brain.
- Composed of different lobes: frontal, parietal, temporal, and occipital.
- Frontal lobe: influences personality.
- Parietal lobe: receives and interprets sensations.
- Occipital lobe: sense of vision.
- Temporal lobe: senses of smell and sound.
Layers of the Cerebrum
- Basal ganglia - internal islands of gray matter that regulates voluntary motor activities- dysfunction may result in tremors (Parkinson's Disease)
The Cerebellum
- Located at the back of the brain.
- Coordinates gait, equilibrium, and voluntary muscle activity.
- Damage to this area results in loss of control of fine movements, posture, and motor learning.
The Brainstem
- Composed of the midbrain, pons, and medulla oblongata.
- Crucial for respiration and cardiovascular system function.
The Diencephalon
- Thalamus: relays sensory stimuli to the brain.
- Hypothalamus: controls body temperature, appetite, body fluids, and endocrine functions.
Limbic system
- Series of structures involved in learning, memory, and emotional responses (e.g., pain, pleasure, affection, anger).
Cerebrospinal Fluid
- Supports, protects, and exchanges materials.
- Forms a watery cushion to protect the brain.
- Circulates to monitor levels of CO2, O2, and pH.
Blood Brain Barrier
- Includes the least permeable capillaries of the body, excluding many potentially harmful substances.
- However, it is not effective against some substances like fats, fat-soluble molecules, respiratory gases, alcohol, nicotine, and anesthesia.
Apply Your Knowledge
- Trauma to the pons can result in the inability to breathe without assistance.
The Synapse
- Region where communication occurs between two neurons or between a neuron and a target cell.
- A neurotransmitter is released from the nerve cell towards the other receiving cell with receptor.
Transmission of Chemical Signals Across the Synapse
- When an electrical impulse reaches the end of a neuron, neurotransmitters are released.
- The neurotransmitters bind to receptors in the next neuron generating a new electrical signal.
The Autonomic Nervous System
- Part of the peripheral nervous system that innervates cardiac muscles, smooth muscles, and glands.
- Functionally divided into:
- Sympathetic nervous system: prepares the body for stressful situations (fight or flight)
- increased heart rate and blood pressure; slows down digestive system; releases adrenaline/noradrenaline (adrenaline-ergic).
- Parasympathetic nervous system: responsible for resting / digesting
- decreases heart rate and blood pressure, stimulates digestive system. Releases Acetylcholine (choline-ergic).
- Sympathetic nervous system: prepares the body for stressful situations (fight or flight)
Nerve Physiology
- Nerve cells are excitable cells.
- Any stimulus changes the membrane potential leading to an impulse (action potential).
- The myelin sheath increases the velocity of nerve transmission.
Starting a Nerve Impulse
- A stimulus depolarizes the neuron's membrane.
- A depolarised membrane allows sodium ions (Na+) to flow inside the membrane.
- The exchange of ions initiates an action potential in the neuron.
The Action Potential
- The action potential (nerve impulse) propagates over the entire axon.
- Potassium ions rush out of the neuron, repolarising the membrane.
- The sodium-potassium pump restores the original ion configuration.
- This action requires ATP.
Action Potential (Nerve Impulse)
- Depolarization: Sodium ions (Na+) pass into the neuron.
- Repolarization: Potassium ions (K+) pass out of the neuron.
- Return to resting potential: by closure of potassium channels and activation of the sodium-potassium pump.
- Local anesthetic blocks sodium channels, preventing pain signal transmission to the brain.
Nerve Impulse Propagation
- Impulses travel faster when nerve fibers have a myelin sheath.
- In multiple sclerosis, the myelin sheath is destroyed (autoimmune disease)
The Reflex Arc
- Reflex: rapid, predictable, and involuntary response to stimuli.
- Reflex arc: direct route from a sensory neuron, to an interneuron, to an effector.
Traumatic Brain Injuries
- Concussion: slight brain injury, no permanent damage.
- Contusion: nervous tissue destruction, nervous tissue does not regenerate, cerebral edema (swelling) may compress and kill brain tissue.
Cerebrovascular Accident (CVA)
- Commonly called a stroke.
- Result of a ruptured blood vessel or clot.
- Brain tissue supplied with oxygen from that blood source dies.
- Loss of some functions or death may result.
Alzheimer's Disease
- Progressive degenerative brain disease.
- Mostly seen in the elderly, can begin in middle age.
- Structural changes include abnormal protein deposits in neurons.
- Victims experience memory loss, irritability, confusion, and eventually hallucinations and death.
Classification of Sensation
- General sensations: superficial (touch, heat, cold), deep, visceral (abnormal conditions).
- Special senses: taste, smell, vision, hearing.
Pain
- An unpleasant emotional and sensory experience that accompanies actual or potential tissue damage.
- Gives conscious awareness of tissue damage.
- Serves as a protection mechanism, prompting removal of the body from danger, promoting healing and avoiding noxious stimuli.
Nociceptors
- Special receptors responding only to noxious stimuli.
- Generate nerve impulses interpreted by the brain as pain.
Fast Pain (Acute)
- Occurs rapidly after stimulus (0.1 second).
- Sharp pain (e.g., needle puncture, cut).
- Not felt in deeper tissues.
- Transmitted to the brain by type A (myelinated) nerve fibers.
Slow Pain (Chronic)
- Begins more slowly and increases in intensity.
- Felt in both superficial and deeper tissues.
- Smaller C nerve fibers (unmyelinated).
- Transmitted to the brain by slowly conducting C nerve fibers.
Visceral Pain
- Often accompanied by strong autonomic and/or somatic reflexes.
- Poorly localized, may be referred.
- Mostly caused by distension of hollow organs or ischemia (localized mechanical trauma may be painless).
Referred Pain
- Pain originating from organs perceived as coming from the skin.
- Site of pain may be distant from the organ.
- Examples: Pain from the heart to the left shoulder; pain from gallbladder to the right shoulder.
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Description
Test your knowledge on the human nervous system with this quiz focusing on its structures, functions, and mechanisms. From the role of the central nervous system to the specifics of neurotransmitters, this quiz covers key concepts essential for understanding human biology.