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Questions and Answers
Which type of sensory receptor responds to stimuli arising outside the body?
Which type of sensory receptor responds to stimuli arising outside the body?
What is not a function of receptors that respond to internal stimuli?
What is not a function of receptors that respond to internal stimuli?
Which of the following sensations is included in the general senses?
Which of the following sensations is included in the general senses?
The modified dendritic endings of sensory neurons are primarily concerned with which type of sensation?
The modified dendritic endings of sensory neurons are primarily concerned with which type of sensation?
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Which of the following properties is true for general sensory receptors?
Which of the following properties is true for general sensory receptors?
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Which sensory function is NOT one of the special senses of the body?
Which sensory function is NOT one of the special senses of the body?
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What percentage of the body's sensory receptors are located in the eye?
What percentage of the body's sensory receptors are located in the eye?
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What structure protects the eyeball by enclosing it?
What structure protects the eyeball by enclosing it?
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Which muscle is responsible for elevating the upper eyelid?
Which muscle is responsible for elevating the upper eyelid?
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What does the term 'palpebral fissure' refer to?
What does the term 'palpebral fissure' refer to?
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Which accessory structure is NOT involved with the eye?
Which accessory structure is NOT involved with the eye?
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How is the sense of touch classified in comparison to the special senses?
How is the sense of touch classified in comparison to the special senses?
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Which part of the brain is involved in processing visual information?
Which part of the brain is involved in processing visual information?
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What is the primary function of the glossopharyngeal nerve (IX)?
What is the primary function of the glossopharyngeal nerve (IX)?
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Which part of the ear is responsible for both hearing and equilibrium?
Which part of the ear is responsible for both hearing and equilibrium?
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How does the body perceive taste?
How does the body perceive taste?
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Which structure connects the middle ear to the nasopharynx?
Which structure connects the middle ear to the nasopharynx?
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Which part of the inner ear houses the equilibrium receptor region called the crista ampullaris?
Which part of the inner ear houses the equilibrium receptor region called the crista ampullaris?
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What are the three components of the auditory ossicles?
What are the three components of the auditory ossicles?
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What is the main role of the hypothalamus in relation to taste?
What is the main role of the hypothalamus in relation to taste?
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Which component of the ear is solely responsible for hearing?
Which component of the ear is solely responsible for hearing?
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Which gland is responsible for tear production?
Which gland is responsible for tear production?
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What is the primary function of tears?
What is the primary function of tears?
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Which structure drains tears into the nasal cavity?
Which structure drains tears into the nasal cavity?
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What type of solution do lacrimal secretions predominantly consist of?
What type of solution do lacrimal secretions predominantly consist of?
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Which muscle is NOT one of the six extrinsic eye muscles?
Which muscle is NOT one of the six extrinsic eye muscles?
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What is the primary role of the four rectus muscles associated with the eye?
What is the primary role of the four rectus muscles associated with the eye?
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Which statement best describes the relationship between receptors and stimuli?
Which statement best describes the relationship between receptors and stimuli?
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Which layer of the eyeball is primarily composed of the cornea and sclera?
Which layer of the eyeball is primarily composed of the cornea and sclera?
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What separates the internal cavity of the eye into anterior and posterior segments?
What separates the internal cavity of the eye into anterior and posterior segments?
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What is the difference between sensation and perception?
What is the difference between sensation and perception?
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What substance fills the anterior segment of the eye?
What substance fills the anterior segment of the eye?
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What does the term 'sensitive to pain' indicate?
What does the term 'sensitive to pain' indicate?
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How can phantom pain be managed during surgery?
How can phantom pain be managed during surgery?
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Which structure is responsible for bending light as it enters the eye?
Which structure is responsible for bending light as it enters the eye?
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Which type of pain is often felt in a different region from where it originates?
Which type of pain is often felt in a different region from where it originates?
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What role do NMDA receptors play in pain perception?
What role do NMDA receptors play in pain perception?
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Which of the following statements is true regarding general senses?
Which of the following statements is true regarding general senses?
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What is a critical factor in pain tolerance and response to pain medications?
What is a critical factor in pain tolerance and response to pain medications?
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What initiates the flow of transducer currents in hair cells?
What initiates the flow of transducer currents in hair cells?
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What type of movements do cristae specifically respond to?
What type of movements do cristae specifically respond to?
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What role do the otoliths play in motion detection?
What role do the otoliths play in motion detection?
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How does the ampullary cupula operate during head rotation?
How does the ampullary cupula operate during head rotation?
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What results from the bending of stereocilia toward the tallest member of their array?
What results from the bending of stereocilia toward the tallest member of their array?
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What is the primary function of the Organ of Corti?
What is the primary function of the Organ of Corti?
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What happens to the stereocilia when sound waves cause the tectorial membrane to shear?
What happens to the stereocilia when sound waves cause the tectorial membrane to shear?
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Which part of the cochlea is responsible for housing mechanoreceptor hair cells?
Which part of the cochlea is responsible for housing mechanoreceptor hair cells?
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Study Notes
Sensory Perception
- Sensory receptors are specialized to respond to environmental changes (stimuli).
- Receptor activation generates graded potentials triggering nerve impulses.
- Sensory awareness (sensation) and interpretation (perception) of stimuli are enabled.
Receptor Classification
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Receptors are classified by the type of stimulus they detect, body location, and structural complexity.
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Functional receptor types include mechanoreceptors, thermoreceptors, photoreceptors, chemoreceptors, and osmoreceptors.
- Mechanoreceptors respond to touch, pressure, vibration, and stretch.
- Thermoreceptors respond to temperature changes.
- Photoreceptors respond to light energy (like those in the retina).
- Chemoreceptors respond to chemicals (like those in smell, taste, and detecting blood chemistry changes).
- Osmoreceptors respond to changes in osmotic pressure.
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Modalities describe the types of sensations detected.
- Nociceptors detect pain-causing stimuli.
- Exteroceptors respond to stimuli from outside the body (e.g., most special sense organs and skin receptors).
- Interoceptors (visceroceptors) respond to stimuli from internal organs and blood vessels.
- Proprioceptors inform the brain about body movements and position.
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Receptors are located in various places, fitting the type:
- Exteroceptors are located in the skin and special sense organs.
- Interoceptors respond to stimuli within internal structures like viscera and blood vessels.
- Proprioceptors detect stretch in skeletal muscles, tendons, joints, ligaments, and connective tissue, updating the brain on body position and movement.
Receptor Structure
- Simple receptors use modified sensory neuron dendrites and are widely distributed throughout the body.
- Receptors for special senses (e.g., vision, hearing, equilibrium, smell, and taste) are housed within complex sense organs.
- For general senses, receptors follow a "one receptor-one function" rule, at times, but also respond to various stimuli; general senses include touch, pressure, stretch, vibration, temperature, pain, and muscle sense.
Non-encapsulated receptors
- These free nerve endings are simple, unspecialized.
- Examples include: thermoreceptors, nociceptors, tactile (Merkel) discs, and hair follicle receptors.
Encapsulated Receptors
- These receptors are characterized by specialized structures (capsules).
- These receptors are mechanoreceptors.
- Examples include: tactile (Meissner's) corpuscles, lamellar (Pacinian) corpuscles, bulbous corpuscles (Ruffini endings), muscle spindles, tendon organs, and joint kinesthetic receptors.
Sensory Processing
- Sensation is the awareness of changes in the internal and external environment.
- Perception is the conscious interpretation of these stimuli.
- Sensory processing happens at three major levels: receptor, circuit, and perceptual.
Levels of Neural Integration
- Sensory receptor level: detects and transduces stimuli into nerve signals.
- Circuit level: pathways of neurons conduct nerve impulses to appropriate parts of the brain.
- Perceptual level: the brain interprets the meaning of the stimuli, a process that depends on the location of the neurons in the sensory cortex.
Perception of Pain
- Pain warns about actual or potential tissue damage, allowing for protective actions.
- Pain is caused by extreme pressure, temperature, and chemicals (histamine, potassium ions, ATP, acids, bradykinin).
- Sensory pathways release neurotransmitters (e.g., glutamate and substance P).
- Some pain impulses are suppressed by endogenous opioids (e.g., endorphins).
Pain Tolerance
- Pain perception is uniform across individuals given the same stimulus.
- Pain tolerance varies significantly by individual.
- Pain sensitivity refers to a lowered pain tolerance, rather than a low pain threshold and is influenced by genetic factors and responses to pain medications.
Visceral and Referred Pain
- Visceral pain arises from stimulation of visceral organ receptors.
- Visceral pain feels as a vague aching, gnawing, or burning sensation.
- Visceral pain can be triggered by tissue stretching, ischemia, or chemicals, and muscle spasms.
- Referred pain is pain originating in one body area that is perceived as coming from a different area.
- Referred pain often involves visceral and somatic pain fibers traveling on the same nerves (examples: Left arm pain during a heart attack).
Clinical Implications
- Chronic pain arises from persistent stimulation of receptors leading to heightened sensitivity (hyperalgesia).
- Chronic pain can result from situations, such as limb loss, leading to phantom limb pain.
Nervous System Senses (General Characteristics)
- Sensory function maintains homeostasis by providing information about the external and internal environments.
- Two main categories: general and special senses.
- General senses: widely distributed receptors throughout the body (e.g., in skin, internal organs, joints).
- Special senses: specialized receptors confined to structures in the head (e.g., eyes, ears, nose, mouth).
Sensory Receptors (General characteristics)
- Collect information from the environment and relay it to the central nervous system (CNS) by sending signals along sensory neurons.
- Link the nervous system to changes and events in the internal and external environments.
- Can be specialized cells or multicellular structures.
Special Senses (Types)
- The special senses include vision, taste, smell, hearing, and equilibrium.
The Eye and Vision
- The eye has approximately 70% of the body's sensory receptors.
- The brain's visual processing area, half of the cerebral cortex, is significantly involved with visual functions.
Accessory structures of the Eyeball
- Eyebrows, eyelids (palpebrae), eyelashes, conjunctiva, lacrimal apparatus (structures that produce tears), extrinsic muscles.
Lacrimal Apparatus
- The lacrimal glands produce tears, which drain into the nasal cavity
- Tears contain a dilute saline solution, mucus, antibodies, and lysozyme (a bacterial enzyme).
Extrinsic Eye Muscles
- Six extrinsic eye muscles allow movement.
- Four rectus muscles (superior, inferior, lateral, medial)
- Two oblique muscles (superior, inferior)
Eyeball Structure
- The eyeball wall is comprised of three layers (fibrous, vascular, and inner).
- The fibrous layer includes the cornea and sclera.
- The vascular layer includes the choroid, ciliary body, and iris.
- The inner layer (retina) has photoreceptor cells (rods and cones), neurons, and glial cells.
- The internal cavity is filled with humors (aqueous and vitreous).
Internal Structure of the Eye
- Cornea, iris, pupil, ciliary zone, ciliary body, lens, anterior segment, posterior segment, scleral venous sinus.
Retina Anatomy: Inner Layer
- The retina has photoreceptor cells (rods and cones), bipolar cells, and ganglion cells.
- The optic disc is the site where the optic nerve leaves the eye (blind spot).
Retina Anatomy: Pigmented Layer
- The pigmented layer is next to the choroid, helping to absorb light and block scattering, phagocytize photoreceptor fragments, and store vitamin A.
Rods and Cones
- Rods are for dim light and peripheral vision, are more numerous and light-sensitive, and don't provide color or sharp images.
- Cones are for bright light and high-resolution color vision.
Fundus of the Eye
- Macula lutea is an area with high cone density, primarily for central vision (acuity).
- Fovea centralis is the precise center of the macula, with the highest cone density.
Internal Chambers and Fluids
- Aqueous humor fills the anterior segment of the eye from the capillaries in the ciliary processes.
- Aqueous humor drains from the scleral venous sinus, located in the anterior eye segment.
- Vitreous humor fills the posterior segment of the eye.
Pupillary Light Reflex
- Pupillary constriction (parasympathetic activation) and dilation (sympathetic activation) regulate light entering the eye.
- Sphincter pupillae muscle constricts the pupil, while the dilatator pupillae dilates it.
PERL/A Eye Exam
- PERRLA is an acronym used to summarize a clinical eye exam, including pupil evaluation:
- Pupils, are equal in size, round, and react to light and accommodation.
The Chemical Senses: Smell and Taste (General characteristics)
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Complementary chemical senses (smell and taste) provide information about the presence or absence of certain substances within the environment.
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Chemoreceptors detect dissolved chemicals in fluids (smell: nasal fluids; taste: saliva).
Sense of Smell (Olfactory Receptors)
- Olfactory epithelium lines the roof of the nasal cavity and covers the superior nasal conchae.
- Olfactory epithelium contains olfactory receptors, which, when stimulated, relay the message to the brain for smell recognition.
Olfactory Bulb
- Olfactory bipolar neurons, covered by a mucus layer that acts as a solvent for odorants.
- Fascicles (made of olfactory nerve fibers) transmit olfactory signals to the brain.
Specificity of Olfactory Receptors
- Humans have approximately 400 different receptor types in the olfactory epithelium.
- Each odorant is perceived by stimulation of multiple receptor types.
- Non-odorant stimuli (such as ammonia and some hot/cold substances) also activate the sensory receptors.
Physiology of Smell
- Odorants must be volatile (gaseous) to be smelled.
- Odorants dissolve in the mucus covering the olfactory epithelium.
Olfactory Transduction Process
- Odorants bind to specific receptors on olfactory cilia, activating associated G proteins that trigger a series of intracellular events leading to ion channel activation producing a nerve impulse.
The Olfactory Pathway
- Signals travel from olfactory receptors through the olfactory nerve, olfactory bulb, olfactory tract (fibers) to the frontal lobe and related areas for smell processing.
- Signals also travel to the hypothalamus and limbic system for emotional responses.
Sense of Taste (Gustatory Pathway)
- Taste receptors are located on papillae (fungiform, foliate, and vallate) of the tongue, as well in the soft palate, pharynx, and epiglottis..
- Taste buds, composed of gustatory epithelial cells and basal cells, house the taste receptors called microvilli (gustatory hairs).
- Tastants (molecules dissolved in saliva) interact with the gustatory hairs, initiating a signal that is transmitted to the brain for taste identification.
Basic Taste Sensations
- The five basic taste sensations are sweet, sour, salty, bitter, and umami.
- umami: taste related to MSG and glutamate
Physiology of Taste
- Tastants (molecules) must dissolve in saliva to be detected.
- Dissolved tastants permeate the taste pores to interact with gustatory hairs.
Gustatory Pathway
- Two cranial nerves carry signals from different parts of the tongue to the brain.
- Facial nerve (VII): carries impulses from anterior two-thirds of the tongue.
- Glossopharyngeal nerve (IX): carries impulses from the posterior one-third of the tongue and the pharynx.
- Vagus nerve (X): carries impulses from the epiglottis and lower pharynx.
- Signals synapse in the solitary nucleus of the medulla, then relay through the thalamus to the gustatory cortex in the insula.
- Hypothalamus and limbic system processes allow for emotional and appreciation of taste.
The Ear: Hearing and Balance
- The ear receives and translates auditory and balance information for processing by the brain.
- The ear is organized into three areas: external, middle, and inner.
External Ear
- The external ear's primary role is to collect sounds and direct them to the middle ear.
- The auricle (pinna) and external auditory meatus.
Middle Ear
- The ossicles (malleus, incus, stapes) transmit sound vibrations from the eardrum to the inner ear.
- The pharyngotympanic (auditory) tube connects the middle ear to the pharynx, equalizing pressure between the middle ear and the atmospheric pressure.
Internal Ear (Labyrinth)
- Composed of the bony and membranous labyrinths.
- The bony labyrinth encloses the membranous labyrinth which contains fluid (endolymph).
- The membranous labyrinth's components, semicircular canals, vestibule, and cochlea, detect and translate rotational, positional, and auditory stimuli and relay signals that inform the brain of head movements.
Semicircular Canals
- Within the semicircular canals, the crista ampullaris contains supporting cells and hair cells which are positioned within a gel-like mass called cupula.
- Sensory hair cells in the crista ampullaris are activated by changes in the endolymph velocity, resulting from rotational head movements.
Cochlea
- The cochlea, containing the organ of Corti and auditory hair cells, translates sound vibrations to nerve impulses.
- The organ of Corti includes the tectorial and basilar membranes, plus hair cells. These components, when stimulated by sound vibrations, initiate a transduction process that leads to nerve impulses.
- Sound frequencies activate specific regions of the basilar membrane.
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Test your knowledge on human sensory receptors with this quiz! Explore questions about the general and special senses, the sensory function of different receptors, and key structures of the eye and ear. Perfect for students studying human anatomy.