HUBI 2004: Gene Expression Regulation in Eukaryotes Quiz
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Questions and Answers

What is the main function of activator proteins in eukaryotic transcriptional regulation?

  • Have no effect on transcription
  • Inhibit transcription
  • Disrupt transcription machinery
  • Promote transcription (correct)

    • How do repressor proteins contribute to gene expression regulation in eukaryotes?

  • Activate transcription
  • Block transcription (correct)
  • Enhance translation
  • Induce transcription

    • What distinguishes eukaryotic regulation from bacterial regulation in terms of control mechanisms?

  • Eukaryotes primarily use positive control mechanisms (correct)
  • Bacteria primarily use positive control mechanisms
  • Bacteria primarily use negative control mechanisms
  • Eukaryotes primarily use negative control mechanisms

    • In the context of gene expression, what constitutes a key factor for ensuring the correct amount of gene product in a cell?

    <p>Regulated transcription with appropriate timing and quantity</p> Signup and view all the answers

    What is a characteristic of the regulatory proteins involved in eukaryotic transcriptional regulation?

    <p>Form large complexes in eukaryotes</p> Signup and view all the answers

    How do levels of RNA transcripts contribute to controlling the amount of each protein or RNA in a eukaryotic cell?

    <p>By influencing the amount of gene product synthesis</p> Signup and view all the answers

    What is responsible for the phenomenon of co-suppression in petunias?

    <p>dsRNA</p> Signup and view all the answers

    Which molecules are processed by DICER and RISC in the context of gene regulation?

    <p>dsRNA</p> Signup and view all the answers

    What is the function of RISC-RNA complexes in gene regulation?

    <p>Degrade targeted RNAs</p> Signup and view all the answers

    Which process can lead to gene silencing based on the given information?

    <p>Changes to DNA methylation</p> Signup and view all the answers

    In the context of gene regulation, what does RNAi-based drugs treat?

    <p>Hereditary transthyretin amyloidosis</p> Signup and view all the answers

    What is responsible for binding to the UASG sites in yeast when galactose is present?

    <p>Gal4</p> Signup and view all the answers

    Which protein interacts with Gal4 to keep it inactive when galactose is absent?

    <p>Gal80</p> Signup and view all the answers

    What is the function of the SAGA complex in gene regulation?

    <p>Recruits Mediator</p> Signup and view all the answers

    Which region of DNA contains the TATA box and binds RNA polymerase II in eukaryotic transcription?

    <p>Core promoter region</p> Signup and view all the answers

    What is the main role of enhancer sequences in eukaryotic gene regulation?

    <p>Regulate transcription from a distance</p> Signup and view all the answers

    What prevents the DNA-binding domain of Gal4 from binding to UASG sites when galactose is absent?

    <p>Gal80 interaction</p> Signup and view all the answers

    Which protein forms a homodimer and interacts with Gal80 in yeast gene regulation?

    <p>Gal4</p> Signup and view all the answers

    What type of protein binds to the core promoter region that contains the TATA box?

    <p>RNA polymerase II</p> Signup and view all the answers

    What is the role of silencer sequences in gene regulation?

    <p>Inhibit transcription</p> Signup and view all the answers

    How do enhancers regulate gene expression in eukaryotes?

    <p>By looping DNA to interact with promoters</p> Signup and view all the answers

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