HSV1 and HSV2: Herpes Simplex Virus
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Questions and Answers

What is the characteristic of the DNA of HSV1 and HSV2?

  • Single-stranded and circular
  • Double-stranded and linear (correct)
  • Single-stranded and linear
  • Triple-stranded and spiral

    • Where does HSV1 primarily replicate?

  • In the endoplasmic reticulum
  • In the mitochondria
  • In the cytoplasm
  • In the nucleus (correct)

    • What is the characteristic appearance of Cowdry bodies in HSV1 and HSV2 infections?

  • Target-like structures (correct)
  • Dot-like structures
  • Ring-like structures
  • Thread-like structures

    • What is the primary mode of transmission of HSV1 and HSV2?

    <p>Through sexual contact and saliva</p> Signup and view all the answers

    What is the common complication of HSV1 infection in the eye?

    <p>Keratoconjunctivitis</p> Signup and view all the answers

    What is the characteristic of herpes labialis caused by HSV1?

    <p>Ulcers on the lips</p> Signup and view all the answers

    What is the site of latency for HSV1?

    <p>Trigeminal ganglia</p> Signup and view all the answers

    What is the characteristic of Tzanck smear in HSV1 and HSV2 infections?

    <p>Presence of multinucleated giant cells</p> Signup and view all the answers

    What is the complication of HSV2 infection in the central nervous system?

    <p>Encephalitis</p> Signup and view all the answers

    What is the characteristic of herpes whitlow caused by HSV1?

    <p>Painful vesicular lesions on the fingers</p> Signup and view all the answers

    What is the primary site of infection for HSV1?

    <p>Upper half of the body</p> Signup and view all the answers

    What is the characteristic appearance of HSV1 ulcers on the lips?

    <p>Snake-like ulcers</p> Signup and view all the answers

    What is the common complication of HSV1 infection in the brain?

    <p>Encephalitis</p> Signup and view all the answers

    What is the characteristic of HSV2 infection in the genital region?

    <p>Painful vesicular lesions</p> Signup and view all the answers

    Where does HSV2 primarily replicate?

    <p>Sacral ganglia</p> Signup and view all the answers

    What is the characteristic of HSV1 latency?

    <p>Latent in trigeminal ganglia</p> Signup and view all the answers

    What is the characteristic of HSV2 transmission?

    <p>Through sex and vertically</p> Signup and view all the answers

    What is the characteristic of Erythema multiforme in HSV1 infection?

    <p>Target lesions on the hands and feet</p> Signup and view all the answers

    What is the characteristic of Tzanck smear in HSV1 and HSV2 infections?

    <p>Multinucleated giant cells</p> Signup and view all the answers

    What is the characteristic of herpes labialis caused by HSV1?

    <p>Ulcers on the lips</p> Signup and view all the answers

    Study Notes

    HSV1 and HSV2

    • Both are DNA viruses and belong to the Herpesviridae family
    • Enveloped viruses with double-stranded linear DNA genomes
    • Replicate in the nucleus

    Characteristics of HSV Infections

    • Transmitted via sexual contact, saliva, and vertically from mother to child
    • Two strains: HSV1 and HSV2, with different symptoms and locations
    • Can cause latent infections, reacting in trigeminal ganglia (HSV1) and sacral ganglia (HSV2)

    HSV1 Infections

    • Typically affects the upper half of the body
    • Causes inflamed lips, ulcers on lips, and Keratoconjunctivitis
    • Can lead to Temporal lobe encephalitis with bizarre behavior
    • Most common cause of sporadic encephalitis
    • Latent in trigeminal ganglia
    • Can cause herpetic whitlow (dew drop on a rose petal appearance)

    HSV2 Infections

    • Typically affects the genital region
    • Causes painful vesicular lesions, inguinal lymphadenopathy, and meningitis
    • Latent in sacral ganglia
    • Can cause neonatal herpes

    Diagnosis and Treatment

    • Diagnosed using Tzanc smear to identify multinucleated giant cells
    • No cure, but can be managed with acyclovir and valcyclovir to prevent breakouts
    • Similar inclusion bodies can be found in cytoplasm in Pox virus infections

    HSV1 and HSV2

    • Both are DNA viruses and belong to the Herpesviridae family
    • Enveloped viruses with double-stranded linear DNA genomes
    • Replicate in the nucleus

    Characteristics of HSV Infections

    • Transmitted via sexual contact, saliva, and vertically from mother to child
    • Two strains: HSV1 and HSV2, with different symptoms and locations
    • Can cause latent infections, reacting in trigeminal ganglia (HSV1) and sacral ganglia (HSV2)

    HSV1 Infections

    • Typically affects the upper half of the body
    • Causes inflamed lips, ulcers on lips, and Keratoconjunctivitis
    • Can lead to Temporal lobe encephalitis with bizarre behavior
    • Most common cause of sporadic encephalitis
    • Latent in trigeminal ganglia
    • Can cause herpetic whitlow (dew drop on a rose petal appearance)

    HSV2 Infections

    • Typically affects the genital region
    • Causes painful vesicular lesions, inguinal lymphadenopathy, and meningitis
    • Latent in sacral ganglia
    • Can cause neonatal herpes

    Diagnosis and Treatment

    • Diagnosed using Tzanc smear to identify multinucleated giant cells
    • No cure, but can be managed with acyclovir and valcyclovir to prevent breakouts
    • Similar inclusion bodies can be found in cytoplasm in Pox virus infections

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    Description

    This quiz covers the characteristics and features of Herpes Simplex Virus 1 and 2, including their structure, replication, and transmission.

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