How well do you know the regulation of glomerular filtration rate?

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Questions and Answers

Autoregulation of GFR maintains GFR despite changes in local blood pressure and ______. Answer: flow.

Reduced blood flow triggers dilation of afferent arteriole and glomerular capillaries and constriction of ______. Answer: efferent arterioles.

Rise in renal blood pressure constricts afferent arterioles and decreases ______ blood flow. Answer: glomerular.

Tubuloglomerular feedback mechanism involves tubular and vascular cells of the ______ apparatus. Answer: juxtaglomerular.

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Macula densa cells detect changes in ______ level of the fluid flowing past. Answer: salt.

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Constriction reduces ______ flow into the glomerulus. Answer: blood.

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Tubuloglomerular feedback mechanism helps to balance the rate of ______ with the rate of fluid reabsorption. Answer: filtration.

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Autoregulation of GFR helps to maintain a stable ______ environment for the cells of the body. Answer: internal.

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Myogenic response is an example of ______ regulation. Answer: intrinsic.

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Afferent arterioles supply blood to the ______. Answer: glomerulus.

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Efferent arterioles carry blood away from the ______. Answer: glomerulus.

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Constriction of afferent arterioles reduces ______. Answer: GFR.

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Study Notes

  • Autoregulation of GFR maintains GFR despite changes in local blood pressure and flow.
  • Myogenic response changes the diameters of afferent arterioles, efferent arterioles, and glomerular capillaries.
  • Reduced blood flow triggers dilation of afferent arteriole and glomerular capillaries and constriction of efferent arterioles.
  • Rise in renal blood pressure constricts afferent arterioles and decreases glomerular blood flow.
  • Tubuloglomerular feedback mechanism involves tubular and vascular cells of the juxtaglomerular apparatus.
  • Macula densa cells detect changes in salt level of the fluid flowing past.
  • Increased salt causes macula densa to secrete ATP and adenosine.
  • ATP and adenosine cause smooth muscles of adjacent afferent arteriole to constrict.
  • Constriction reduces blood flow into the glomerulus.
  • Constriction reduces GFR.

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