How Well Do You Know Mitochondrial Citrate and Acetyl CoA Metabolism?
8 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which molecule is exported to the cytosol for the production of cytosolic acetyl CoA and oxaloacetate?

  • Acetyl CoA
  • Citrate (correct)
  • Isocitrate
  • Oxaloacetate

    • What is the fate of excess acetyl CoA in the mitochondrial matrix when isocitrate dehydrogenase is inhibited by large amounts of ATP?

  • It is used for fatty acid synthesis
  • It is converted to citrate (correct)
  • It is transported to the cytosol
  • It accumulates in the mitochondrial matrix

    • What enzyme cleaves citrate in the cytosol to produce acetyl CoA and oxaloacetate?

  • Isocitrate dehydrogenase
  • ATP-citrate lyase (correct)
  • Citrate synthase
  • Fatty acid synthase

    • What is the role of citrate in the transport of acetyl CoA?

    <p>It acts as a transporter for acetyl CoA</p> Signup and view all the answers

    What is the product of the cleavage of citrate by ATP-citrate lyase in the cytosol?

    <p>Acetyl CoA and oxaloacetate</p> Signup and view all the answers

    What is the effect of high ATP concentrations on isocitrate dehydrogenase?

    <p>It is inhibited</p> Signup and view all the answers

    What is the purpose of cleaving citrate to produce acetyl CoA in the cytosol?

    <p>To use in fatty acid synthesis</p> Signup and view all the answers

    What is the carbon content of acetyl CoA produced from the cleavage of citrate?

    <p>2 carbon</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser