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Questions and Answers
What is the main function of Ferroportin-l and Hephaestirf?
What is the main function of Ferroportin-l and Hephaestirf?
- Transporting iron as Fe+2 from enterocytes and macrophage engulfed effete RBCs to circulation (correct)
- Transporting iron as Fe+3 from enterocytes to circulation
- Transporting iron as Fe+3 from circulation to enterocytes
- Transporting iron as Fe+2 from circulation to enterocytes
Where is Ferroportin-q found and what is its function?
Where is Ferroportin-q found and what is its function?
- Found in the bone marrow and controls iron exit from cells into portal plasma
- Found in the basolateral surface of duodenal enterocytes, placenta, macrophage and hepatocytes and controls iron exit from cells into portal plasma (correct)
- Found in the basolateral surface of duodenal enterocytes, placenta, macrophage and hepatocytes and controls iron uptake
- Found in the apotransferrin-Tf of bone marrow and controls iron uptake
What is the role of Hepcidin in iron homeostasis?
What is the role of Hepcidin in iron homeostasis?
- It acts as a receptor for Ferroportin-q
- It controls the exit of iron from the cells into portal plasma
- It controls the uptake of iron into the cells from portal plasma
- It acts as a regulatory hormone of iron homeostasis by binding to Ferroportin-q and causing its internalization and degradation (correct)
