Tuberculosis is caused by tubercle bacilli in the lung.
Macrophages invade infected tissue and wall off the lesion to limit transmission.
Primary lesion includes Tcel, foamy giant cell, infected macrophage, and firm caseous core.
Persisting mycobacteria can be found in lesion-free tissue and lymph nodes.
Late stages of tuberculosis result in fibrosis and reduced functional lung tissue.
This causes increased work on respiratory muscles and reduced vital capacity.
The respiratory membrane surface area is reduced and thickness is increased.
This causes diminished pulmonary diffusing capacity.
There is an abnormal ventilation perfusion ratio in the lung.
Overall pulmonary diffusion of O2 and CO2 is reduced.

Test your knowledge of tuberculosis with this informative quiz! Learn about the causes, symptoms, and stages of this infectious disease. Discover how macrophages and mycobacteria play a role in its progression, and understand the impact it has on the respiratory system. With questions about the respiratory membrane and ventilation perfusion ratio, this quiz will challenge your understanding of pulmonary diffusing capacity. Become an expert on tuberculosis by taking this quiz today!