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Questions and Answers
What is the main cause of tuberculosis?
What is the main cause of tuberculosis?
- A fungus
- A bacterium (correct)
- A virus
- A parasite
What is the primary lesion in tuberculosis made up of?
What is the primary lesion in tuberculosis made up of?
- Tcel, foamy giant cell, and infected macrophage
- Foamy giant cell, infected macrophage, and firm caseous core (correct)
- Foamy giant cell and infected macrophage
- Tcel and infected macrophage
How does tuberculosis affect the respiratory system?
How does tuberculosis affect the respiratory system?
- It reduces functional lung tissue and pulmonary diffusing capacity (correct)
- It increases vital capacity
- It reduces ventilation perfusion ratio in the lung
- It increases respiratory muscle strength
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Study Notes
- Tuberculosis is caused by tubercle bacilli in the lung.
- Macrophages invade infected tissue and wall off the lesion to limit transmission.
- Primary lesion includes Tcel, foamy giant cell, infected macrophage, and firm caseous core.
- Persisting mycobacteria can be found in lesion-free tissue and lymph nodes.
- Late stages of tuberculosis result in fibrosis and reduced functional lung tissue.
- This causes increased work on respiratory muscles and reduced vital capacity.
- The respiratory membrane surface area is reduced and thickness is increased.
- This causes diminished pulmonary diffusing capacity.
- There is an abnormal ventilation perfusion ratio in the lung.
- Overall pulmonary diffusion of O2 and CO2 is reduced.
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