How Much Do You Know About Transdermal Drug Delivery?

1. Transdermal delivery systems are patches applied to the skin to release active ingredients.
2. They are suitable for drugs that easily cross the skin barrier, have the right hydrophilic/lipophilic balance, are small enough to diffuse through the stratum corneum, and are non-irritating and non-sensitizing.
3. Transdermal delivery has advantages over oral or IV administration, including continuous delivery of drugs with short biological half-lives, lower risk of over- or under-dosing, and simplified dosing schedules.
4. The rate of drug release is regulated to ensure optimal absorption.
5. Factors affecting absorption include temperature, hydration of the stratum corneum, surface area of application, and thickness of the stratum corneum.
6. The skin barrier can be eliminated or modified to increase drug penetration.
7. Promoters of absorption can increase hydration, solubility, and fluidity of lipids in the skin.
8. Examples of promoters of absorption include short-chain alcohols, glycerol, and propylene glycol.
9. Other methods for increasing absorption include the use of cyclodextrins, phospholipids, and surfactants.
10. Transdermal delivery allows for precise dosing and easy discontinuation of treatment.

Are you familiar with transdermal delivery systems? Test your knowledge and learn more about these patches that release active ingredients through the skin. In this quiz, you will discover the advantages of transdermal delivery over other administration methods, factors affecting drug absorption, and ways to increase penetration. From factors affecting drug release rate to promoters of absorption, you'll explore the science behind transdermal delivery systems. Take the quiz now and see how much you know about this innovative drug delivery method!