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Questions and Answers
What is the primary component of collagen in hyaline cartilage?
What is the primary component of collagen in hyaline cartilage?
- Type II collagen (correct)
- Type IV collagen
- Type I collagen
- Type III collagen
What is the function of metalloproteinases in cartilage?
What is the function of metalloproteinases in cartilage?
- To provide lubrication to cartilage
- To degrade cartilage matrix (correct)
- To maintain the resilience of cartilage
- To synthesize extracellular matrix
What is the role of isogenous groups in cartilage?
What is the role of isogenous groups in cartilage?
- To degrade cartilage matrix
- To provide lubrication to cartilage
- To maintain the resilience of cartilage
- To synthesize extracellular matrix (correct)
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Study Notes
- Chondrocytes synthesize and maintain the extracellular matrix of hyaline cartilage.
- Chondrocytes can be found singularly or in isogenous groups.
- Isogenous groups represent recently divided cells that produce matrix material.
- Metalloproteinases degrade cartilage matrix, allowing cells to reposition and expand.
- Cartilage contains 60%-70% water and inorganic salts for resilience and lubrication.
- Cartilage matrix contains collagens, PGs, and non-collagenous proteins.
- Type II collagen makes up 90%-95% of collagen in hyaline cartilage.
- Type II collagen forms a fibrillary meshwork for tensile strength and shape.
- Dry weight of cartilage matrix is 40%-70% collagen.
- Age and location affect the composition of cartilage.
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