3 Questions
Which of the following is NOT a pathway through which complement can be activated?
Innate
Which cells produce complement proteins?
Hepatocytes, tissue macrophages, and epithelial cells of the GI
What is required for complement proteins to be activated?
They require cleavage
Study Notes
- Complement is a group of serum proteins that enhance aspects of innate immunity and some effects of antibodies.
- It exists in an inactive form and is activated sequentially as a cascade.
- Complement proteins are proenzymes that require cleavage for activation.
- Complement components are designated by numbers or letters.
- Complement can be activated through three major pathways: classical, alternative, and lectin.
- The classical pathway is antibody-dependent and triggered by the formation of antigen-antibody complexes.
- The alternative pathway is antibody-independent and stimulated by antigens directly.
- The lectin pathway is also antibody-independent but resembles the classical pathway.
- Complement proteins are produced by hepatocytes, tissue macrophages, and epithelial cells of the GI.
- The heat-labile complement is a component of normal plasma.
"Test your knowledge on the fascinating world of complement proteins and their role in enhancing immunity! This quiz will challenge you to identify the different complement components, understand their activation pathways, and explore their production in various cells. With questions ranging from the classical pathway to the heat-labile complement, this quiz is perfect for anyone interested in immunology and the body's defense mechanisms. Sharpen your skills and showcase your expertise with this informative and exciting quiz!"
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