Questions and Answers
What is a telomere?
What are telomeres made of?
When is replication at the chromosome end a problem in somatic cells?
What removes all the RNA primers during end replication problem in somatic cells?
Signup and view all the answers
What fills the gap created by the removal of RNA primers during end replication problem in somatic cells?
Signup and view all the answers
Why can't the gap created at the 5’ end of the lagging strand be filled with DNA by polymerase during end replication problem in somatic cells?
Signup and view all the answers
What does the gap created at the 5’ end of the lagging strand during end replication problem in somatic cells result in?
Signup and view all the answers
Can the final gap created at the 5’ end of the lagging strand be filled in germ, stem & cancer cells?
Signup and view all the answers
What are RNase H and FEN1 responsible for during end replication problem in somatic cells?
Signup and view all the answers
Which strand experiences end replication problem during somatic cell division?
Signup and view all the answers
What is a telomere?
Signup and view all the answers
What are telomeres made of?
Signup and view all the answers
When is replication at the chromosome end a problem in somatic cells?
Signup and view all the answers
What removes all the RNA primers during end replication problem in somatic cells?
Signup and view all the answers
What fills the gap created by the removal of RNA primers during end replication problem in somatic cells?
Signup and view all the answers
Why can't the gap created at the 5’ end of the lagging strand be filled with DNA by polymerase during end replication problem in somatic cells?
Signup and view all the answers
What does the gap created at the 5’ end of the lagging strand during end replication problem in somatic cells result in?
Signup and view all the answers
Can the final gap created at the 5’ end of the lagging strand be filled in germ, stem & cancer cells?
Signup and view all the answers
What are RNase H and FEN1 responsible for during end replication problem in somatic cells?
Signup and view all the answers
Which strand experiences end replication problem during somatic cell division?
Signup and view all the answers
What is a telomere?
Signup and view all the answers
What is the composition of telomeres?
Signup and view all the answers
Why is replication at the chromosome end (telomere) a problem in somatic cells?
Signup and view all the answers
What removes all the RNA primers during end replication problem in somatic cells?
Signup and view all the answers
What fills the gap created by the removal of RNA primers during end replication problem in somatic cells?
Signup and view all the answers
Why can't the gap created at the 5’ end of the lagging strand be filled with DNA by polymerase during end replication problem in somatic cells?
Signup and view all the answers
Can the final gap created at the 5’ end of the lagging strand be filled in somatic cells?
Signup and view all the answers
Which cells can fill the final gap created at the 5’ end of the lagging strand?
Signup and view all the answers
What is the function of telomerase?
Signup and view all the answers
What is the consequence of telomere shortening?
Signup and view all the answers
What is the role of telomerase in germ, stem, and cancer cells?
Signup and view all the answers
What is the reason for the permanent gap (overhangs) in somatic cells?
Signup and view all the answers