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What is the temperature-dependent dimorphism exhibited by Talaromyces marneffei?
What is the temperature-dependent dimorphism exhibited by Talaromyces marneffei?
- The fungus grows as a mold form at 25°C and as a yeast at 37°C (correct)
- The fungus grows as a yeast form at both 25°C and 37°C
- The fungus grows as a mold form at both 25°C and 37°C
- The fungus grows as a yeast form at 25°C and as a mold at 37°C
What is the presumed mode of transmission for T. marneffei?
What is the presumed mode of transmission for T. marneffei?
- Direct contact with infected humans
- Ingestion of contaminated food or water
- Inhalation of environmental conidia (correct)
- Bite of infected animals
What is the most common manifestation of disseminated infection in profoundly immunosuppressed patients with a CD4+ T-cell count ≤100 cells/mm3?
What is the most common manifestation of disseminated infection in profoundly immunosuppressed patients with a CD4+ T-cell count ≤100 cells/mm3?
- Characteristic skin lesions
- Respiratory and gastrointestinal abnormalities
- Disseminated infection involving multiple organ systems (correct)
- Fever and weight loss
What is the characteristic feature of Paracoccidioidomycosis that can be seen on Giemsa- or Wright-stained smears?
What is the characteristic feature of Paracoccidioidomycosis that can be seen on Giemsa- or Wright-stained smears?
What is the recommended treatment for joint involvement in paradoxical IRIS?
What is the recommended treatment for joint involvement in paradoxical IRIS?
What is the recommended initial therapy for antifungal treatment according to international guidelines?
What is the recommended initial therapy for antifungal treatment according to international guidelines?
What is the primary concern for not widely adopting the strategy of primary prophylaxis with itraconazole in Asia?
What is the primary concern for not widely adopting the strategy of primary prophylaxis with itraconazole in Asia?
What is the current classification of Talaromyces marneffei?
What is the current classification of Talaromyces marneffei?
What is the main disadvantage of PCR-based assays for diagnosing Paracoccidioidomycosis?
What is the main disadvantage of PCR-based assays for diagnosing Paracoccidioidomycosis?
What is the relapse rate for patients who are compliant on secondary prophylaxis with itraconazole and effective ART?
What is the relapse rate for patients who are compliant on secondary prophylaxis with itraconazole and effective ART?
What is the role of macrophages in host defense against T. marneffei?
What is the role of macrophages in host defense against T. marneffei?
What are the common laboratory findings in patients with disseminated infection caused by intracellular pathogens?
What are the common laboratory findings in patients with disseminated infection caused by intracellular pathogens?
What is the critical virulence factor of T. marneffei in a mouse model?
What is the critical virulence factor of T. marneffei in a mouse model?
What is the on-treatment mortality of disseminated infection in both HIV-infected and non-HIV-infected patients?
What is the on-treatment mortality of disseminated infection in both HIV-infected and non-HIV-infected patients?
What did the multicenter itraconazole versus amphotericin B for talaromycosis trial (IVAP) demonstrate about the effectiveness of amphotericin B and itraconazole?
What did the multicenter itraconazole versus amphotericin B for talaromycosis trial (IVAP) demonstrate about the effectiveness of amphotericin B and itraconazole?
Which antigen detection assay has the highest sensitivity and specificity for diagnosing Paracoccidioidomycosis?
Which antigen detection assay has the highest sensitivity and specificity for diagnosing Paracoccidioidomycosis?
Which of the following is true about talaromycosis?
Which of the following is true about talaromycosis?
What is the recommended maintenance antifungal therapy for patients with co-infections of cryptococcal meningitis and talaromycosis?
What is the recommended maintenance antifungal therapy for patients with co-infections of cryptococcal meningitis and talaromycosis?
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