How much do you know about glycogen synthesis?
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Questions and Answers

Which of the following is true about glycogenin?

  • It needs another enzyme to form a new glycogen branch
  • It produces α-1,6 branches
  • It can only add one glucose molecule at a time
  • It has a tyrosine with a hydroxyl group (correct)

Which enzyme transfers a terminal fragment of 6-7 glucose residues to an internal glucose residue at the C-6 hydroxyl position?

  • Glycogen synthase
  • Glycogenin
  • Amylo-(1,4-1,6)-transglycosylase (correct)
  • Branching enzyme

What is the site of the 1st glucose to attach to glycogenin?

  • A histidine with a hydroxyl group
  • A threonine with a hydroxyl group
  • A serine with a hydroxyl group
  • A tyrosine with a hydroxyl group (correct)

How many glucose molecules are added to glycogenin before the new glycogen chain is ready to be acted upon by glycogen synthase?

<p>Around 7 (C)</p> Signup and view all the answers

What is the function of glycogen synthase?

<p>To synthesize glycogen from glucose (C)</p> Signup and view all the answers

What is the term used to describe amylo-(1,4-1,6)-transglycosylase?

<p>Branching enzyme (A)</p> Signup and view all the answers

What is the position of the internal glucose residue that receives the terminal fragment of 6-7 glucose residues from the branching enzyme?

<p>C-6 hydroxyl position (A)</p> Signup and view all the answers

What is the name of the enzyme that adds glucose molecules to glycogenin to form a new glycogen branch?

<p>Glycogenin (B)</p> Signup and view all the answers

What is the minimum length of the polymer from which the branching enzyme transfers a terminal fragment of 6-7 glucose residues to an internal glucose residue at the C-6 hydroxyl position?

<p>11 glucose residues (C)</p> Signup and view all the answers

What is the function of the α-1,6 branches in glycogen?

<p>To increase solubility and accessibility of stored glucose (D)</p> Signup and view all the answers

What is the name of the enzyme that breaks down glycogen into glucose?

<p>Glycogen phosphorylase (B)</p> Signup and view all the answers

What is the name of the enzyme that transfers a terminal fragment of 3-4 glucose residues from the non-reducing end of a glycogen chain to the C-4 hydroxyl group of an adjacent glucose residue?

<p>Debranching enzyme (B)</p> Signup and view all the answers

Which of the following is true about glycogenin?

<p>It has a tyrosine with a hydroxyl group (B)</p> Signup and view all the answers

Which enzyme transfers a terminal fragment of 6-7 glucose residues to an internal glucose residue at the C-6 hydroxyl position?

<p>Amylo-(1,4-1,6)-transglycosylase (D)</p> Signup and view all the answers

What is the site of the 1st glucose to attach to glycogenin?

<p>A tyrosine with a hydroxyl group (A)</p> Signup and view all the answers

How many glucose molecules are added to glycogenin before the new glycogen chain is ready to be acted upon by glycogen synthase?

<p>Around 7 (B)</p> Signup and view all the answers

What is the function of glycogen synthase?

<p>To break down glycogen into glucose (A)</p> Signup and view all the answers

What is the term used to describe amylo-(1,4-1,6)-transglycosylase?

<p>Branching enzyme (C)</p> Signup and view all the answers

What is the position of the internal glucose residue that receives the terminal fragment of 6-7 glucose residues from the branching enzyme?

<p>C-6 hydroxyl position (B)</p> Signup and view all the answers

What is the name of the enzyme that adds glucose molecules to glycogenin to form a new glycogen branch?

<p>Glycogenin (C)</p> Signup and view all the answers

What is the minimum length of the polymer from which the branching enzyme transfers a terminal fragment of 6-7 glucose residues to an internal glucose residue at the C-6 hydroxyl position?

<p>11 glucose residues (B)</p> Signup and view all the answers

What is the function of the α-1,6 branches in glycogen?

<p>To increase solubility and accessibility of stored glucose (D)</p> Signup and view all the answers

What is the name of the enzyme that breaks down glycogen into glucose?

<p>Glycogen phosphorylase (B)</p> Signup and view all the answers

What is the name of the enzyme that transfers a terminal fragment of 3-4 glucose residues from the non-reducing end of a glycogen chain to the C-4 hydroxyl group of an adjacent glucose residue?

<p>Debranching enzyme (C)</p> Signup and view all the answers

Which enzyme is responsible for forming a new glycogen branch by adding glucose molecules without the need of another enzyme?

<p>Glycogenin (A)</p> Signup and view all the answers

What is the site of the first glucose to attach to glycogenin?

<p>A tyrosine with a hydroxyl group (B)</p> Signup and view all the answers

How many glucose molecules are added to glycogenin before the new glycogen chain is ready to be acted upon by glycogen synthase?

<p>Around 7 (B)</p> Signup and view all the answers

What is the name of the enzyme responsible for producing α-1,6 branches in glycogen?

<p>Amylo- (1 , 4 - 1 , 6)- transglycosylase (C)</p> Signup and view all the answers

What is the minimum length of a polymer of glucose residues that can be used by the branching enzyme to produce α-1,6 branches in glycogen?

<p>10-11 glucose residues (C)</p> Signup and view all the answers

What is the position of the internal glucose residue that the branching enzyme transfers the terminal fragment of glucose residues to?

<p>C-6 hydroxyl position (C)</p> Signup and view all the answers

What is the name of the amino acid with a hydroxyl group that serves as the site of the first glucose to attach to glycogenin?

<p>Tyrosine (A)</p> Signup and view all the answers

What is the name of the enzyme that can add glucose molecules on top of each other to form a new glycogen branch without the need of another enzyme?

<p>Glycogenin (D)</p> Signup and view all the answers

What is the name of the enzyme that acts upon the new glycogen chain after the addition of around seven glucose molecules by glycogenin?

<p>Glycogen synthase (A)</p> Signup and view all the answers

What is the name of the enzyme that transfers a terminal fragment of glucose residues to an internal glucose residue at the C-6 hydroxyl position to produce α-1,6 branches in glycogen?

<p>Amylo- (1 , 4 - 1 , 6)- transglycosylase (D)</p> Signup and view all the answers

What is the minimum length of a polymer of glucose residues that the branching enzyme can transfer a terminal fragment of glucose residues from to produce α-1,6 branches in glycogen?

<p>10-11 glucose residues (B)</p> Signup and view all the answers

What is the position of the hydroxyl group on the tyrosine that serves as the site of the first glucose to attach to glycogenin?

<p>C-6 hydroxyl position (B)</p> Signup and view all the answers
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