How much do you know about glycogen synthesis?
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Questions and Answers

Which of the following is true about glycogenin?

  • It needs another enzyme to form a new glycogen branch
  • It produces α-1,6 branches
  • It can only add one glucose molecule at a time
  • It has a tyrosine with a hydroxyl group (correct)
  • Which enzyme transfers a terminal fragment of 6-7 glucose residues to an internal glucose residue at the C-6 hydroxyl position?

  • Glycogen synthase
  • Glycogenin
  • Amylo-(1,4-1,6)-transglycosylase (correct)
  • Branching enzyme
  • What is the site of the 1st glucose to attach to glycogenin?

  • A histidine with a hydroxyl group
  • A threonine with a hydroxyl group
  • A serine with a hydroxyl group
  • A tyrosine with a hydroxyl group (correct)
  • How many glucose molecules are added to glycogenin before the new glycogen chain is ready to be acted upon by glycogen synthase?

    <p>Around 7</p> Signup and view all the answers

    What is the function of glycogen synthase?

    <p>To synthesize glycogen from glucose</p> Signup and view all the answers

    What is the term used to describe amylo-(1,4-1,6)-transglycosylase?

    <p>Branching enzyme</p> Signup and view all the answers

    What is the position of the internal glucose residue that receives the terminal fragment of 6-7 glucose residues from the branching enzyme?

    <p>C-6 hydroxyl position</p> Signup and view all the answers

    What is the name of the enzyme that adds glucose molecules to glycogenin to form a new glycogen branch?

    <p>Glycogenin</p> Signup and view all the answers

    What is the minimum length of the polymer from which the branching enzyme transfers a terminal fragment of 6-7 glucose residues to an internal glucose residue at the C-6 hydroxyl position?

    <p>11 glucose residues</p> Signup and view all the answers

    What is the function of the α-1,6 branches in glycogen?

    <p>To increase solubility and accessibility of stored glucose</p> Signup and view all the answers

    What is the name of the enzyme that breaks down glycogen into glucose?

    <p>Glycogen phosphorylase</p> Signup and view all the answers

    What is the name of the enzyme that transfers a terminal fragment of 3-4 glucose residues from the non-reducing end of a glycogen chain to the C-4 hydroxyl group of an adjacent glucose residue?

    <p>Debranching enzyme</p> Signup and view all the answers

    Which of the following is true about glycogenin?

    <p>It has a tyrosine with a hydroxyl group</p> Signup and view all the answers

    Which enzyme transfers a terminal fragment of 6-7 glucose residues to an internal glucose residue at the C-6 hydroxyl position?

    <p>Amylo-(1,4-1,6)-transglycosylase</p> Signup and view all the answers

    What is the site of the 1st glucose to attach to glycogenin?

    <p>A tyrosine with a hydroxyl group</p> Signup and view all the answers

    How many glucose molecules are added to glycogenin before the new glycogen chain is ready to be acted upon by glycogen synthase?

    <p>Around 7</p> Signup and view all the answers

    What is the function of glycogen synthase?

    <p>To break down glycogen into glucose</p> Signup and view all the answers

    What is the term used to describe amylo-(1,4-1,6)-transglycosylase?

    <p>Branching enzyme</p> Signup and view all the answers

    What is the position of the internal glucose residue that receives the terminal fragment of 6-7 glucose residues from the branching enzyme?

    <p>C-6 hydroxyl position</p> Signup and view all the answers

    What is the name of the enzyme that adds glucose molecules to glycogenin to form a new glycogen branch?

    <p>Glycogenin</p> Signup and view all the answers

    What is the minimum length of the polymer from which the branching enzyme transfers a terminal fragment of 6-7 glucose residues to an internal glucose residue at the C-6 hydroxyl position?

    <p>11 glucose residues</p> Signup and view all the answers

    What is the function of the α-1,6 branches in glycogen?

    <p>To increase solubility and accessibility of stored glucose</p> Signup and view all the answers

    What is the name of the enzyme that breaks down glycogen into glucose?

    <p>Glycogen phosphorylase</p> Signup and view all the answers

    What is the name of the enzyme that transfers a terminal fragment of 3-4 glucose residues from the non-reducing end of a glycogen chain to the C-4 hydroxyl group of an adjacent glucose residue?

    <p>Debranching enzyme</p> Signup and view all the answers

    Which enzyme is responsible for forming a new glycogen branch by adding glucose molecules without the need of another enzyme?

    <p>Glycogenin</p> Signup and view all the answers

    What is the site of the first glucose to attach to glycogenin?

    <p>A tyrosine with a hydroxyl group</p> Signup and view all the answers

    How many glucose molecules are added to glycogenin before the new glycogen chain is ready to be acted upon by glycogen synthase?

    <p>Around 7</p> Signup and view all the answers

    What is the name of the enzyme responsible for producing α-1,6 branches in glycogen?

    <p>Amylo- (1 , 4 - 1 , 6)- transglycosylase</p> Signup and view all the answers

    What is the minimum length of a polymer of glucose residues that can be used by the branching enzyme to produce α-1,6 branches in glycogen?

    <p>10-11 glucose residues</p> Signup and view all the answers

    What is the position of the internal glucose residue that the branching enzyme transfers the terminal fragment of glucose residues to?

    <p>C-6 hydroxyl position</p> Signup and view all the answers

    What is the name of the amino acid with a hydroxyl group that serves as the site of the first glucose to attach to glycogenin?

    <p>Tyrosine</p> Signup and view all the answers

    What is the name of the enzyme that can add glucose molecules on top of each other to form a new glycogen branch without the need of another enzyme?

    <p>Glycogenin</p> Signup and view all the answers

    What is the name of the enzyme that acts upon the new glycogen chain after the addition of around seven glucose molecules by glycogenin?

    <p>Glycogen synthase</p> Signup and view all the answers

    What is the name of the enzyme that transfers a terminal fragment of glucose residues to an internal glucose residue at the C-6 hydroxyl position to produce α-1,6 branches in glycogen?

    <p>Amylo- (1 , 4 - 1 , 6)- transglycosylase</p> Signup and view all the answers

    What is the minimum length of a polymer of glucose residues that the branching enzyme can transfer a terminal fragment of glucose residues from to produce α-1,6 branches in glycogen?

    <p>10-11 glucose residues</p> Signup and view all the answers

    What is the position of the hydroxyl group on the tyrosine that serves as the site of the first glucose to attach to glycogenin?

    <p>C-6 hydroxyl position</p> Signup and view all the answers

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