How much do you know about bleeding disorders and platelet function?
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Questions and Answers

What does the Capillary Resistance Test detect?

  • Platelet aggregation using aggregating agents and an aggregometer
  • Platelet adhesiveness using Glass Bead Retention Test
  • Abnormalities in capillary walls or thrombocytopenia (correct)
  • Abnormalities in platelet number and function

    • What is the purpose of the Lee-White whole blood clotting time test?

  • To measure the time for venous blood to form a solid clot. (correct)
  • To test for dysfibrinogenemia
  • To screen for factor deficiencies in the intrinsic and common pathways.
  • To measure the time for blood to clot after calcium is added to platelet-poor plasma

    • What is the primary concern in specimen collection for hemostasis testing?

  • Preventing contamination with tissue thromboplastin (correct)
  • Hemolysis
  • Using an inappropriate container
  • Improper temperature

    • Which of the following can cause false shortening of clotting tests in hemostasis testing?

    <p>Contamination with tissue thromboplastin</p> Signup and view all the answers

    What does the Lee-White whole blood clotting time measure?

    <p>The time for venous blood to form a solid clot.</p> Signup and view all the answers

    Which type of needle is most commonly used for hemostasis sample collection?

    <p>20-gauge needle</p> Signup and view all the answers

    Which method is used to measure Bleeding Time?

    <p>Modified Duke Method and Ivy Method</p> Signup and view all the answers

    Which of the following is released from injured cells and activates thromboplastin?

    <p>Tissue thromboplastin</p> Signup and view all the answers

    Which pathway(s) of blood coagulation does the activated partial thromboplastin time screen for factor deficiencies in?

    <p>Both intrinsic and common pathways</p> Signup and view all the answers

    What does the plasma recalcification time measure?

    <p>The time for blood to clot after calcium is added to platelet-poor plasma</p> Signup and view all the answers

    Which anticoagulant is preferred for coagulation testing?

    <p>Trisodium citrate</p> Signup and view all the answers

    Which pathway does the activated partial thromboplastin time screen for factor deficiencies in?

    <p>Intrinsic pathway</p> Signup and view all the answers

    What is the purpose of the prothrombin time test?

    <p>To monitor anticoagulant therapy.</p> Signup and view all the answers

    What does Platelet Aggregation Test measure?

    <p>Platelet aggregation using aggregating agents and an aggregometer</p> Signup and view all the answers

    What is the ideal ratio of blood to anticoagulant for patients with normal hematocrit?

    <p>9:1</p> Signup and view all the answers

    What is the ideal ratio of blood to anticoagulant for coagulation testing?

    <p>9:1</p> Signup and view all the answers

    What does the prothrombin time test for?

    <p>Factor deficiencies in the extrinsic and common pathways</p> Signup and view all the answers

    What is the Platelet Estimation on Peripheral Blood Smear used for?

    <p>To detect abnormalities in platelet number and function</p> Signup and view all the answers

    Which anticoagulant is unsuitable for coagulation testing?

    <p>EDTA</p> Signup and view all the answers

    What does the international normalized ratio provide a means of standardizing?

    <p>PT reporting worldwide</p> Signup and view all the answers

    Which factor is unstable in the presence of EDTA?

    <p>Factor VIII</p> Signup and view all the answers

    What are the Aggregation Disorders mentioned in the text?

    <p>Adhesion Defects and Abnormalities in Risotocetin</p> Signup and view all the answers

    What can cause prolonged clotting times in hemostasis testing?

    <p>Changes in pH</p> Signup and view all the answers

    Which test is used to distinguish factor deficiencies and involves testing normal plasma, adsorbed plasma, and aged serum?

    <p>Substitution assay</p> Signup and view all the answers

    What is the purpose of the international normalized ratio?

    <p>To provide a means of standardizing PT reporting worldwide</p> Signup and view all the answers

    Which anticoagulant is unsuitable for coagulation testing?

    <p>EDTA</p> Signup and view all the answers

    What are some other tests used in hemostasis testing?

    <p>The reptilase time, thrombin time, and substitution assay</p> Signup and view all the answers

    What conditions can the results of hemostasis tests indicate?

    <p>All of the above</p> Signup and view all the answers

    What is the Clot Retraction Time used for?

    <p>To measure the time for the clot to retract from the walls of the tube</p> Signup and view all the answers

    What is the preferred concentration of sodium citrate for coagulation testing?

    <p>3.2%</p> Signup and view all the answers

    What is the recommended centrifugation speed and time for obtaining platelet-poor plasma?

    <p>2000 g for 10 minutes</p> Signup and view all the answers

    What is the substitution assay used for?

    <p>To distinguish factor deficiencies.</p> Signup and view all the answers

    Which test measures the time for blood to clot after calcium is added to platelet-poor plasma?

    <p>Plasma recalcification time</p> Signup and view all the answers

    Which diseases are mentioned in the text?

    <p>Hemophilia, von Willebrand disease, and Glanzmann's thrombasthenia</p> Signup and view all the answers

    What is the recommended centrifugation speed and time to obtain platelet-poor plasma?

    <p>2000 g for 10 minutes</p> Signup and view all the answers

    What is the Platelet Adhesiveness used for?

    <p>To detect platelet adhesiveness</p> Signup and view all the answers

    What pathways of blood coagulation does the prothrombin time test screen for factor deficiencies in?

    <p>Both extrinsic and common pathways</p> Signup and view all the answers

    What conditions can be indicated by the results of hemostasis tests?

    <p>Hypofibrinogenemia, dysfibrinogenemia, and immunologic antithrombin deficiencies</p> Signup and view all the answers

    Study Notes

    1. Bleeding time measures time for a standard wound to stop bleeding.
    2. Methods for Bleeding Time: Modified Duke Method and Ivy Method.
    3. Platelet Count detects abnormalities in platelet number and function.
    4. Capillary Resistance Test detects abnormalities in capillary walls or thrombocytopenia.
    5. Clot Retraction Time measures the time for the clot to retract from the walls of the tube.
    6. Platelet Estimation on Peripheral Blood Smear uses a formula to estimate platelet count.
    7. Platelet Aggregation Test measures platelet aggregation using aggregating agents and an aggregometer.
    8. Platelet Adhesiveness uses Glass Bead Retention Test to detect platelet adhesiveness.
    9. Aggregation Disorders include Adhesion Defects and Abnormalities in Risotocetin.
    10. Diseases: Hemophilia, von Willebrand disease, and Glanzmann's thrombasthenia.

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    Description

    Test your knowledge on bleeding disorders and platelet function with this informative quiz. Explore different methods for bleeding time and platelet count, as well as tests for platelet aggregation and adhesiveness. Learn about common aggregation disorders and diseases like Hemophilia, von Willebrand disease, and Glanzmann's thrombasthenia. Sharpen your understanding of these important medical concepts and challenge yourself with this quiz.

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