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Questions and Answers
What is Azidothymidine (AZT)?
What is Azidothymidine (AZT)?
- An analog of GTP
- An analog of TTP (correct)
- An analog of ATP
- An analog of CTP
What is the mechanism of action of Azidothymidine (AZT)?
What is the mechanism of action of Azidothymidine (AZT)?
- It inhibits viral fusion with host cells
- It inhibits viral RNA synthesis
- It interferes with viral DNA chain elongation (correct)
- It inhibits viral attachment to host cells
What is the role of the 3'-OH group in DNA chain elongation?
What is the role of the 3'-OH group in DNA chain elongation?
- It prevents formation of phosphodiester bonds
- It cleaves the phosphate group from the incoming nucleotide
- It forms hydrogen bonds with the incoming nucleotide (correct)
- It stabilizes the DNA helix
What is the effect of the lack of 3'-OH group in Azidothymidine?
What is the effect of the lack of 3'-OH group in Azidothymidine?
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What is the therapeutic use of Azidothymidine?
What is the therapeutic use of Azidothymidine?
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What is the function of TTP in DNA replication?
What is the function of TTP in DNA replication?
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What is the significance of the azido group in Azidothymidine?
What is the significance of the azido group in Azidothymidine?
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