10 Questions
What is an aerosol?
A liquid suspended in a gas
Why is aerosolized medication preferred over other forms of medication?
It offers higher local drug concentration in the lung
What factors affect particle size in an aerosol?
Substance, method used, and environmental conditions
What is deposition in relation to aerosol?
The amount of drug inhaled
What are the primary mechanisms for deposition of small particles (1-5 µm) in the lung?
Both B and C
What is aging in relation to aerosol?
The process by which an aerosol suspension changes over time
Which factors affect deposition of aerosol in the lungs?
Both A and B
What types of inhalers are capable of delivering medication to target airway regions?
Both A and B
What is the primary deposition mechanism for very small particles deep within the lung (<3 µm)?
Brownian motion
What is the primary deposition mechanism for larger particles (>5 µm)?
Inertial impaction
Study Notes
- An aerosol is a suspension of solid or liquid particles in gas.
- Aerosolized medication offers higher local drug concentration in the lung with lower systemic levels.
- Particle size depends on the substance, method used, and environmental conditions.
- Deposition is the amount of drug inhaled and only a fraction of the emitted aerosol will be inhaled.
- Factors affecting deposition include inertial impaction, sedimentation, and Brownian motion.
- Sedimentation is the primary mechanism for deposition of small particles (1-5 µm).
- Brownian motion is the primary deposition mechanism for very small particles deep within the lung (<3 µm).
- Aging is the process by which an aerosol suspension changes over time.
- Other factors affecting deposition include inspiratory flow rate, flow pattern, respiratory rate, tidal volume, I:E ratio, and breath-holding.
- Metered Dose Inhalers and DPIs are capable of delivering medication to target airway regions.
Test your knowledge on aerosol therapy with our quiz! Learn about the different mechanisms of deposition, factors affecting drug delivery, and the benefits of aerosolized medication. Explore the role of particle size, aging, and inhaler types in optimizing drug delivery to the lungs. Improve your understanding of aerosol therapy and its applications in respiratory medicine.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
