Host Defense Mechanisms Overview

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Questions and Answers

What is the primary function of tears?

  • To produce saliva and vaginal secretions
  • To wash away pathogens from the urinary tract
  • To protect the eyes (correct)
  • To act as a flushing mechanism

Which of the following is NOT considered a chemical barrier in the body's first line of defense?

  • Sebum
  • Blood transferrins
  • Gastric juices
  • Normal microbiota (correct)

What is the primary function of lysozymes in the body's defenses?

  • To bind to available iron and starve bacteria
  • To produce a slightly acidic environment on the skin
  • To act as a flushing mechanism against pathogens
  • To break down the cell wall of bacteria (correct)

What is the primary role of blood transferrins in the body's defenses?

<p>To remove available iron, which bacteria need for growth (A)</p> Signup and view all the answers

What is the main reason the skin's pH is slightly acidic?

<p>To produce the chemical factor of sebum, a waxy lipid (B)</p> Signup and view all the answers

Which of the following is considered a biological barrier in the body's first line of defense?

<p>Normal microbiota (B)</p> Signup and view all the answers

What is the primary function of gastric juices in the body's defenses?

<p>To destroy most bacteria, except for those that can tolerate acidity (A)</p> Signup and view all the answers

What is the main function of T cells and B cells?

<p>Play a role in adaptive immunity (A)</p> Signup and view all the answers

Which type of white blood cell is a first responder in the innate immune system?

<p>Neutrophils (B)</p> Signup and view all the answers

What is the first phase of phagocytosis?

<p>Chemotaxis (C)</p> Signup and view all the answers

Which cell type is responsible for engulfing pathogens through phagocytosis?

<p>Phagocytes (D)</p> Signup and view all the answers

What is a phagosome?

<p>Endocytosed vesicle containing the pathogen (C)</p> Signup and view all the answers

Which phase of phagocytosis involves the formation of a phagolysosome?

<p>Digestion (D)</p> Signup and view all the answers

What is the role of opsonization in the immune response?

<p>To coat the surface of something (B)</p> Signup and view all the answers

What is the function of histamine release from mast cells?

<p>To increase blood vessel permeability (B)</p> Signup and view all the answers

What happens when complement proteins bind to mast cells?

<p>Release of histamine (A)</p> Signup and view all the answers

How does the membrane attack complex (MAC) affect pathogens?

<p>It creates holes in the pathogen's cell membrane leading to bursting (D)</p> Signup and view all the answers

What is a strategy used by some microbes to evade the complement system?

<p>Producing capsules to prevent complement protein binding (D)</p> Signup and view all the answers

Which process involves attracting phagocytes to the site of infection?

<p>Inflammation (A)</p> Signup and view all the answers

What is the main outcome of the complement system's cytolysis process?

<p>Pathogens bursting due to holes created in their cell wall (A)</p> Signup and view all the answers

What is the role of the first line of host defense?

<p>To provide physical barriers to prevent pathogens from entering the body (C)</p> Signup and view all the answers

Which of the following is NOT a component of the first line of host defense?

<p>Antibodies (A)</p> Signup and view all the answers

What is the primary function of the keratin protein in the top layer of intact skin?

<p>To reinforce and protect the underlying layers of skin (D)</p> Signup and view all the answers

How does the ciliary escalator contribute to the first line of host defense?

<p>It moves mucus and trapped pathogens towards the throat for removal (D)</p> Signup and view all the answers

What is the primary role of the lacrimal apparatus in the first line of host defense?

<p>To flush away pathogens from the eye (D)</p> Signup and view all the answers

Which of the following statements about intact skin is TRUE?

<p>Intact skin has a continuous layering of closely packed epithelial cells (C)</p> Signup and view all the answers

What is the purpose of the mucus secreted by the mucous membranes?

<p>To trap pathogens and facilitate their removal from the body (A)</p> Signup and view all the answers

What are complement proteins unable to do easily?

<p>Bind to bacterial cells (D)</p> Signup and view all the answers

What prevents the formation of the membrane attack complex (MAC)?

<p>Bacterial enzymes (A)</p> Signup and view all the answers

How do bacteria protect themselves against complement proteins?

<p>By inactivating complement proteins (D)</p> Signup and view all the answers

What do interferons (IFNs) interfere with?

<p>Viral infections in animal cells (C)</p> Signup and view all the answers

What type of cells produce interferons (IFNs)?

<p>Animal host cells (D)</p> Signup and view all the answers

What is the primary function of interferons (IFNs)?

<p>To alert neighboring cells of a potential viral infection (D)</p> Signup and view all the answers

How do interferons (IFNs) initiate an antiviral response in uninfected cells?

<p>By binding to cell membrane receptors (B)</p> Signup and view all the answers

What is the first step in the mechanism of action of interferons?

<p>Virus enters animal host cell and multiplies (D)</p> Signup and view all the answers

What do interferons (IFNs) cause uninfected neighboring cells to do?

<p>Heighten their antiviral defenses (D)</p> Signup and view all the answers

What is the final step in the mechanism of action of interferons?

<p>Uninfected cell produces antiviral proteins (A)</p> Signup and view all the answers

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