Hormones Release Stimuli

Hormones Release Stimuli Overview

• Gastrin is stimulated by the presence of protein and distention of the stomach, while it is inhibited by acid.
• Cholecystokinin (CCK) is released primarily in response to fat and protein, serving a notable role in digestion.
• Secretin is significantly stimulated by both acid and fat, and less so by protein and carbohydrate.
• Glucose-dependent insulinotropic peptide (GLIP) is mainly stimulated by carbohydrates and proteins, with a less significant response to acid and fat.
• Motilin is more responsive to fat and the activity of the nervous system, showing secondary responses to protein, while being less influenced by carbs and acid.

Hormone Response Summary

• Gastrin:

  • Stimuli: Protein, distention
  • Inhibited by: Acid

• CCK:

  • Stimuli: Fat, protein
  • Not affected by: Carbohydrates or nerve signals

• Secretin:

  • Stimuli: Acid, fat
  • Minor influence from: Protein, carbohydrate

• GLIP:

  • Key stimulus: Carbohydrate
  • Sensitive to: Protein
  • Less responsive to: Acid and fat

• Motilin:

  • Responds to: Fat and nerve activity
  • Minor response to: Protein, secondary influence from acid and carbohydrates

Importance of Hormonal Interplay

• Understanding hormone release stimuli helps in grasping digestive processes and can influence therapeutic approaches in gastrointestinal disorders.
• This interplay demonstrates the body's complex regulatory mechanisms for digestion, highlighting essential nutrients (proteins, fats, carbohydrates) and physiological responses (distention, acid).