Podcast
Questions and Answers
What type of hormone is inappropriately produced by a tumor of the adrenal medulla?
What type of hormone is inappropriately produced by a tumor of the adrenal medulla?
Which of the following is an example of ectopic hormone production?
Which of the following is an example of ectopic hormone production?
Which tumor is associated with the inappropriate production of calcitonin?
Which tumor is associated with the inappropriate production of calcitonin?
What is the clinical relevance of ectopic hormone production by tumor cells?
What is the clinical relevance of ectopic hormone production by tumor cells?
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Which of the following factors determine the type of hormone produced by a pituitary gland tumor?
Which of the following factors determine the type of hormone produced by a pituitary gland tumor?
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Study Notes
Hormones as Tumor Markers
- Hormones can serve as tumor markers in two ways:
Inappropriate Production by Endocrine Gland Tumor
- Pituitary gland tumors can produce excess pituitary hormones, depending on the affected cell type.
- Adrenal medulla tumors (Pheochromocytoma) produce excessive catecholamine.
- Medullary thyroid carcinoma produces excessive calcitonin, specifically in parafollicular C cells.
Ectopic Hormone Production
- Tumor cells can produce abnormal levels of hormones or hormone-like substances not typically produced by the extraendocrine system.
- This type of production has limited clinical relevance due to its lack of specificity.
- Example: Malignant tumors may produce PTH-like hormones.
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Description
Learn how hormones can be tumor markers in endocrine gland tumors, including pituitary gland tumors, adrenal medulla tumors, and medullary thyroid carcinoma. Understand the inappropriate production of hormones in these tumors.