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Questions and Answers
What type of hormone is inappropriately produced by a tumor of the adrenal medulla?
What type of hormone is inappropriately produced by a tumor of the adrenal medulla?
- Catecholamine (correct)
- Pituitary hormone
- Calcitonin
- PTH-like hormone
Which of the following is an example of ectopic hormone production?
Which of the following is an example of ectopic hormone production?
- Production of PTH-like hormone by malignant tumors (correct)
- Production of pituitary hormone in pituitary tumor
- Production of calcitonin in medullary thyroid carcinoma
- Production of catecholamine in adrenal medulla tumor
Which tumor is associated with the inappropriate production of calcitonin?
Which tumor is associated with the inappropriate production of calcitonin?
- Adrenal medulla tumor
- Pituitary gland tumor
- Malignant tumor producing PTH-like hormone
- Medullary thyroid carcinoma (correct)
What is the clinical relevance of ectopic hormone production by tumor cells?
What is the clinical relevance of ectopic hormone production by tumor cells?
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Which of the following factors determine the type of hormone produced by a pituitary gland tumor?
Which of the following factors determine the type of hormone produced by a pituitary gland tumor?
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Study Notes
Hormones as Tumor Markers
- Hormones can serve as tumor markers in two ways:
Inappropriate Production by Endocrine Gland Tumor
- Pituitary gland tumors can produce excess pituitary hormones, depending on the affected cell type.
- Adrenal medulla tumors (Pheochromocytoma) produce excessive catecholamine.
- Medullary thyroid carcinoma produces excessive calcitonin, specifically in parafollicular C cells.
Ectopic Hormone Production
- Tumor cells can produce abnormal levels of hormones or hormone-like substances not typically produced by the extraendocrine system.
- This type of production has limited clinical relevance due to its lack of specificity.
- Example: Malignant tumors may produce PTH-like hormones.
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