Chapter 25 | GIT Function & Regulation
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Questions and Answers

What accompanies the secretion of protons in the gastrointestinal system?

  • Release of sodium ions
  • Release of potassium ions
  • Release of chloride ions
  • Release of bicarbonate ions (correct)

What disrupts the barrier that prevents autodigestion of the mucosa by gastric secretions?

  • Infection with Helicobacter pylori (correct)
  • Increased mucus production
  • Reduction in acid secretion
  • Elevated bicarbonate secretion

Which of the following drugs can lead to gastric and duodenal ulceration?

  • Antidepressants
  • Antihistamines
  • Antibiotics
  • Aspirin (correct)

What is a primary cause of ulceration in the Zollinger-Ellison syndrome?

<p>Hypersecretion of acid (A)</p> Signup and view all the answers

Where are most gastrinomas found in patients with Zollinger-Ellison syndrome?

<p>Pancreas (D)</p> Signup and view all the answers

What is commonly used to combat pain and treat arthritis, but can contribute to ulceration?

<p>NSAIDs (A)</p> Signup and view all the answers

What is the purpose of releasing trypsin as an inactive precursor?

<p>To prevent digestion of the pancreas (B)</p> Signup and view all the answers

Why does the pancreas secrete a trypsin inhibitor?

<p>To prevent the activation of trypsin (A)</p> Signup and view all the answers

What is the primary control mechanism for the secretion of pancreatic juice?

<p>Hormonal control (C)</p> Signup and view all the answers

Why are bile acids important in the digestion and absorption of fats?

<p>To facilitate fat digestion and absorption (D)</p> Signup and view all the answers

What is the function of bile in the body?

<p>To dispose of cholesterol (A)</p> Signup and view all the answers

What gives bile its golden yellow color?

<p>Bilirubin and biliverdin (B)</p> Signup and view all the answers

What is the role of Substance P in the gastrointestinal tract?

<p>Increasing the motility of the small intestine (D)</p> Signup and view all the answers

Where are the two major nerve fiber networks intrinsic to the gastrointestinal tract located?

<p>Between the outer longitudinal and middle circular muscle layers (C)</p> Signup and view all the answers

How many sensory neurons, interneurons, and motor neurons are found in the human gastrointestinal system?

<p>More than in the spinal cord (D)</p> Signup and view all the answers

What is the principal physiological action of gastrin?

<p>Stimulation of gastric acid and pepsin secretion (B)</p> Signup and view all the answers

What is the enteric nervous system sometimes referred to, and why?

<p>The little brain for its size (C)</p> Signup and view all the answers

How is gastrin secretion affected by the presence of protein digestion products in the stomach?

<p>Stimulates gastrin secretion (B)</p> Signup and view all the answers

How does Substance P affect growth hormone secretion?

<p>Indirectly affects it through receptors in the pituitary (A)</p> Signup and view all the answers

Which cells in the gastric mucosa produce gastrin?

<p>G cells (C)</p> Signup and view all the answers

What are the functions of the myenteric plexus (Auerbach plexus) within the gastrointestinal tract?

<p>Controls muscle movements between certain layers (D)</p> Signup and view all the answers

How does acid in the antrum affect gastrin secretion?

<p>Inhibits gastrin secretion (B)</p> Signup and view all the answers

What are hormones or paracrines in the gastrointestinal system primarily secreted by?

<p>Nerve cells and gland cells (A)</p> Signup and view all the answers

How do gastrointestinal hormones like gastrin primarily act in the body?

<p>Paracrine and endocrine fashion (C)</p> Signup and view all the answers

Which plexus is primarily involved in the control of intestinal secretion?

<p>Submucous plexus (B)</p> Signup and view all the answers

Which neurotransmitter is NOT mentioned as part of the gastrointestinal system?

<p>Dopamine (B)</p> Signup and view all the answers

The gastrointestinal system evolved to permit controlled nutrient uptake in __________ organisms.

<p>Multicellular (B)</p> Signup and view all the answers

Which component of bile is essential in the chemical alteration of meal components for absorption?

<p>Enzymes (B)</p> Signup and view all the answers

What is the primary function of the myenteric plexus?

<p>Motor control of smooth muscle layers (A)</p> Signup and view all the answers

Which gas is mentioned as part of the neurotransmitters in the gastrointestinal system?

<p>Nitric oxide (B)</p> Signup and view all the answers

What is the main action of gastrin in the gastrointestinal system?

<p>Stimulating pancreatic enzyme secretion (B)</p> Signup and view all the answers

Which stimuli inhibit gastrin secretion in the gastrointestinal system?

<p>Somatostatin (A)</p> Signup and view all the answers

Where are endocrine cells secreting cholecystokinin (CCK) found?

<p>In the upper small intestine (B)</p> Signup and view all the answers

What is the primary function of CCK in the gastrointestinal system?

<p>Promoting bile flow (C)</p> Signup and view all the answers

Which neurotransmitter is involved in increasing gastrin secretion through vagal discharge?

<p>Cholecystokinin releasing peptide (GRP) (D)</p> Signup and view all the answers

What is the effect of luminal peptides and amino acids on gastrin secretion?

<p>Increase gastrin secretion (D)</p> Signup and view all the answers

What is the primary function of bile acids in the digestive process?

<p>Facilitate the absorption of vitamins (A)</p> Signup and view all the answers

Which of the following is NOT a modality for gastrointestinal regulation mentioned in the text?

<p>Intrinsic motility (D)</p> Signup and view all the answers

How does endocrine regulation differ from paracrine regulation in gastrointestinal function?

<p>Endocrine signals target distant organs, while paracrine signals act locally (D)</p> Signup and view all the answers

Which component of the gastrointestinal system has extensive neural connections to both the central nervous system and an autonomous nervous system?

<p>Intestinal system (B)</p> Signup and view all the answers

What is the main function of the enteric nervous system within the gastrointestinal tract?

<p>Coordinate sensory and secretomotor neurons (B)</p> Signup and view all the answers

How do gastrointestinal hormones differ from paracrines in their mode of action?

<p>Hormones act via the bloodstream, while paracrines act locally (B)</p> Signup and view all the answers

What is the main function of Substance P in the gastrointestinal tract?

<p>Increasing motility of the small intestine (C)</p> Signup and view all the answers

Which nervous system is sometimes referred to as the 'little brain' due to its autonomous function in regulating gastrointestinal activities?

<p>Enteric Nervous System (D)</p> Signup and view all the answers

How many major networks of nerve fibers are intrinsic to the gastrointestinal tract?

<p>Two (B)</p> Signup and view all the answers

What is the collective term for the approximately 100 million neurons found in the gastrointestinal system?

<p>Enteric Nervous System (B)</p> Signup and view all the answers

What stimulates parietal and chief cells in the stomach?

<p>Acetylcholine released from enteric nerve endings (D)</p> Signup and view all the answers

During which phase is gastric secretion predominantly activated by vagal input?

<p>Cephalic phase (C)</p> Signup and view all the answers

What serves as a feedback inhibitory signal to shut off gastric secretion?

<p>Release of somatostatin (D)</p> Signup and view all the answers

What is the key mechanism that terminates gastric secretion after a meal moves from the stomach to the small intestine?

<p>Presence of meal constituents (D)</p> Signup and view all the answers

What is the primary function of mitochondria in gastric parietal cells?

<p>Supplying energy for the proton pump (B)</p> Signup and view all the answers

What plays a crucial role in buffering gastric acidity and terminating gastric secretion post-meal?

<p>Presence of meal constituents (D)</p> Signup and view all the answers

What is the primary function of gastrin in the gastrointestinal system?

<p>Stimulating growth of the stomach mucosa (A)</p> Signup and view all the answers

How is gastrin secretion affected by the presence of amino acids in the stomach?

<p>It activates G cells to secrete more gastrin (C)</p> Signup and view all the answers

What is the effect of acid in the antrum on gastrin secretion?

<p>Inhibits gastrin secretion (C)</p> Signup and view all the answers

Which factors affect the secretion of gastrointestinal hormones like gastrin?

<p>Rate of discharge of the vagus nerves (D)</p> Signup and view all the answers

What is the role of somatostatin in relation to gastrin?

<p>Inhibits gastric acid and pepsin secretion (C)</p> Signup and view all the answers

How do hormones and paracrines function within the gastrointestinal system?

<p>By acting in a paracrine manner and sometimes entering circulation (C)</p> Signup and view all the answers

What is the primary function of the myenteric plexus within the gastrointestinal tract?

<p>Primarily involved in motor control (C)</p> Signup and view all the answers

Which neurotransmitter is NOT mentioned as part of the gastrointestinal system?

<p>Endorphin (C)</p> Signup and view all the answers

What is the main role of the submucous plexus in the gastrointestinal system?

<p>Innervates glandular epithelium and controls intestinal secretion (C)</p> Signup and view all the answers

What activity describes the function of digestive secretions in the gastrointestinal system?

<p>Breaking down macromolecules for absorption (C)</p> Signup and view all the answers

Which neurotransmitter contributes to gastrointestinal regulation by affecting smooth muscle contractions?

<p>Nitric oxide (NO) (A)</p> Signup and view all the answers

How are some peptides released by the gastrointestinal system different from others?

<p>Serving as hormones (A)</p> Signup and view all the answers

What is the evolutionary advantage of the gastrointestinal system being functionally continuous with the outside environment?

<p>Enhanced nutrient absorption (A)</p> Signup and view all the answers

Which component is NOT found in digestive secretions that chemically alter meal components?

<p>Macronutrients (C)</p> Signup and view all the answers

How do paracrine factors differ from hormones in their role within the gastrointestinal system?

<p>Act on nearby cells (B)</p> Signup and view all the answers

Which gas molecule serves as a neurotransmitter involved in gastrointestinal regulation?

<p>Nitric oxide (NO) (A)</p> Signup and view all the answers

What is the primary purpose of digestive secretions in relation to meal components?

<p>Chemically alter components for absorption (B)</p> Signup and view all the answers

How do neurotransmitters like serotonin differ from ATP in their influence on gastrointestinal activities?

<p>Control muscle contraction differently (A)</p> Signup and view all the answers

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