Hormones and Exercise Physiology

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Questions and Answers

The magnitude of a hormone's effect on a tissue is most directly determined by which combination of factors?

  • The number of receptors available on the tissue and the hormone concentration in the plasma. (correct)
  • The hormone's chemical structure and the hormone concentration in the blood.
  • The rate of hormone production and the rate of hormone degradation.
  • The hormone's chemical structure and the number of receptors on the tissue.

Which combination of hormones is released from the anterior pituitary gland?

  • Growth hormone and anti-diuretic hormone
  • Luteinizing hormone and somatomedins
  • Thyroid-stimulating hormone and thyroxine
  • Prolactin and adrenocorticotropic hormone (correct)

From which structure are catecholamines secreted?

  • Adrenal cortex
  • Parathyroid gland
  • Adrenal medulla (correct)
  • Pancreas

Aldosterone, a hormone involved in sodium and potassium balance, is secreted by which of the following?

<p>The adrenal cortex (A)</p> Signup and view all the answers

Which mechanism contributes to maintaining plasma glucose levels during exercise?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following are examples of slow-acting hormones that help maintain plasma glucose during prolonged exercise?

<p>Cortisol and growth hormone (C)</p> Signup and view all the answers

How does exercise facilitate increased glucose transport into muscle cells?

<p>Through GLUT4 receptors (B)</p> Signup and view all the answers

How are hormones classified based on their solubility?

<p>Water-soluble and lipid-soluble (steroid) hormones (A)</p> Signup and view all the answers

Which hormone primarily aids in sodium conservation and potassium excretion, impacting fluid and electrolyte balance?

<p>Aldosterone (D)</p> Signup and view all the answers

Which combination of hormones can elevate blood glucose levels?

<p>Epinephrine, glucagon, and cortisol (B)</p> Signup and view all the answers

What term describes the sensation of shortness of breath?

<p>Dyspnea (C)</p> Signup and view all the answers

During rest, is expiration passive or active?

<p>True (B)</p> Signup and view all the answers

What role does the respiratory system play in acid-base balance during exercise?

<p>Removing $H^+$ from the blood by the $HCO_3^-$ reaction, hyperventilating and allowing more CO2 to be exhaled. (B)</p> Signup and view all the answers

What is the typical atmospheric pressure at rest?

<p>760 mm Hg (B)</p> Signup and view all the answers

A key factor in whether respiratory muscle fatigue occurs during exercise depends on what intensity level?

<p>False (A)</p> Signup and view all the answers

How does the specificity of a hormone receptor contribute to the hormone's effect on a target tissue?

<p>It ensures that the hormone only affects tissues with the appropriate receptors. (D)</p> Signup and view all the answers

If the anterior pituitary gland is removed, which of the following hormones would be most immediately affected?

<p>Growth Hormone (B)</p> Signup and view all the answers

A patient presents with symptoms of prolonged stress and elevated blood glucose levels. Which of the following glandular structures is most likely involved in these symptoms?

<p>Adrenal cortex (D)</p> Signup and view all the answers

What is the primary mechanism by which aldosterone contributes to the maintenance of blood pressure?

<p>Enhancing sodium reabsorption in the kidneys (C)</p> Signup and view all the answers

How do the effects of glucagon and insulin interact to maintain plasma glucose levels?

<p>Glucagon raises blood glucose, while insulin lowers it. (B)</p> Signup and view all the answers

What is the role of GLUT4 in regulating glucose transport, and how is it affected by exercise?

<p>GLUT4 stimulates glucose transport, and exercise increases its translocation to the cell membrane. (C)</p> Signup and view all the answers

How does the classification of a hormone as either water-soluble or lipid-soluble influence its mechanism of action?

<p>Water-soluble hormones activate second messenger systems, while lipid-soluble hormones directly influence gene expression. (A)</p> Signup and view all the answers

An athlete is experiencing muscle weakness and increased fatigue during training. Blood tests reveal an electrolyte imbalance with low sodium levels. Which hormone is most likely deficient?

<p>Aldosterone (B)</p> Signup and view all the answers

Which combination of hormonal responses would you expect to observe during prolonged, moderate-intensity exercise?

<p>Decreased insulin, increased glucagon, increased epinephrine (C)</p> Signup and view all the answers

What is the physiological basis for the sensation of dyspnea during intense exercise?

<p>An increased awareness of the elevated ventilation rate (B)</p> Signup and view all the answers

During quiet breathing at rest, what forces primarily drive the process of expiration?

<p>Elastic recoil of the lungs and relaxation of inspiratory muscles (A)</p> Signup and view all the answers

How does the respiratory system compensate for metabolic acidosis induced during high-intensity exercise?

<p>By increasing the rate and depth of breathing to exhale more CO2 (B)</p> Signup and view all the answers

How would an increase in altitude affect atmospheric pressure and, consequently, alveolar oxygen partial pressure?

<p>Atmospheric pressure decreases, and alveolar oxygen partial pressure decreases. (D)</p> Signup and view all the answers

In which scenario is respiratory muscle fatigue most likely to limit exercise performance?

<p>During high-intensity exercise in individuals with respiratory disease (B)</p> Signup and view all the answers

How does active recovery between high-intensity sprints aid in lactate removal compared to passive recovery?

<p>Active recovery helps maintain blood flow, enhancing lactate removal by oxidation and gluconeogenesis. (C)</p> Signup and view all the answers

How do the concentrations of hormones in the plasma and the number of available receptors interact to affect a tissue?

<p>The magnitude of a hormone's effect is influenced by both the hormone concentration in the plasma and the number of available receptors. (D)</p> Signup and view all the answers

Which set of hormones are secreted by another gland and affect secretion of the anterior pituitary?

<p>Prolactin and adrenocorticotropic hormone (B)</p> Signup and view all the answers

What physiological response would you expect from the secretion of catecholamines during exercise?

<p>Elevated heart rate and bronchodilation to improve oxygen delivery. (D)</p> Signup and view all the answers

Under what condition would aldosterone secretion be most beneficial?

<p>During periods of dehydration or sodium deficiency (B)</p> Signup and view all the answers

Which concurrent processes are most responsible for maintaining plasma glucose levels during prolonged exercise?

<p>Increased liver gluconeogenesis and fat mobilization. (B)</p> Signup and view all the answers

What roles do cortisol and growth hormone play in maintaining plasma glucose during exercise?

<p>They block the action of insulin, mobilizing free fatty acids and stimulating gluconeogenesis. (B)</p> Signup and view all the answers

How does the activation of specific signaling pathways impact glucose transport into muscle during exercise?

<p>It stimulates the translocation of GLUT4 transporters, facilitating glucose uptake independently of insulin. (B)</p> Signup and view all the answers

How do the solubility properties of hormones affect their mechanism of action on target cells?

<p>Water-soluble hormones bind to cell surface receptors, whereas lipid-soluble hormones can directly cross the cell membrane and affect gene expression. (D)</p> Signup and view all the answers

Which effect would you expect from administering a drug that mimics aldosterone?

<p>Increased sodium retention and increased potassium excretion in the urine. (C)</p> Signup and view all the answers

How do epinephrine, glucagon, and cortisol influence blood glucose levels?

<p>They promote glycogenolysis and gluconeogenesis, increasing glucose release into the blood. (A)</p> Signup and view all the answers

Which scenario would most likely cause dyspnea in an athlete?

<p>Failure to adequately readjust breathing to match metabolic demand during intense exercise. (D)</p> Signup and view all the answers

What mechanical process primarily drives quiet expiration when the body is at rest?

<p>Elastic recoil of the lungs and relaxation of inspiratory muscles (D)</p> Signup and view all the answers

How does the respiratory system compensate for increases in acidity during exercise?

<p>By hyperventilating to exhale more carbon dioxide, which reduces hydrogen ion concentration (A)</p> Signup and view all the answers

How would a rapid increase in altitude from sea level to 10,000 feet affect one's ability to take in oxygen?

<p>It would decrease atmospheric pressure, leading to lower alveolar oxygen partial pressure. (A)</p> Signup and view all the answers

Under which conditions would respiratory muscle fatigue be most likely to affect exercise performance?

<p>During high-intensity exercise sustained near maximal levels (D)</p> Signup and view all the answers

Flashcards

Hormone Effect on Tissue

The effect a hormone has on a tissue is directly related to the concentration of the hormone in the plasma and the number of receptors available.

Anterior Pituitary Hormones

Hormones released from the anterior pituitary include prolactin and adrenocorticotropic hormone.

Catecholamine Source

Catecholamines are secreted from the adrenal cortex.

Aldosterone Source

Aldosterone is secreted by the adrenal cortex.

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Maintaining Plasma Glucose

Maintaining plasma glucose during exercise is accomplished by liver gluconeogenesis, liver glycogenolysis and mobilization of FFA

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Slow-Acting Glucose Hormones

Examples of slow-acting hormones responsible for the maintenance of plasma glucose are insulin and glucagon.

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Exercise Glucose Transport

Exercise increases glucose transport into muscle through GLUT 4 receptors.

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Hormone Solubility

Hormones fall into two basic categories based on solubility: water-soluble and lipid-soluble (steroid) hormones.

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Aldosterone Function

Aldosterone aids in sodium conservation and potassium excretion.

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Hormones Elevating Blood Glucose

Epinephrine, glucagon, and cortisol can elevate blood glucose levels.

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Dyspnea

Shortness of breathing is called Dyspnea.

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Pulmonary System Limitation

In healthy, young subjects, the pulmonary system DOES NOT limit exercise performance during prolonged submaximal exercise (<90% VO2 max).

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Intrapleural Pressure

Intrapleural pressure is lower than atmospheric pressure.

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Diaphragm Contraction

When the diaphragm contracts, the lungs inspire.

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Central Chemoreceptor Sensitivity

Central chemoreceptors are sensitive to increases in PCO2 and decreases in pH.

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Deoxyhemoglobin

Deoxyhemoglobin is hemoglobin carrying carbon dioxide.

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Residual Volume

The volume of gas remaining in the lungs after a maximum expiration.

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Minute Ventilation Calculation

The tidal volume multiplied by the alveolar ventilation.

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Respiratory Acid-Base Balance

During exercise, the respiratory system helps acid-base balance by removing H+ via HCO3- reaction.

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Atmospheric Pressure

Normal atmospheric pressure at rest is 760 mm Hg.

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Passive Expiration

At rest, expiration is passive.

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Respiratory Muscle Fatigue

Respiratory muscle fatigue can occur during high-intensity exercise (>90% VO2 max).

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Active Recovery

Performing active recovery between sprints is best for quickest lactic acid reduction.

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Aerobic Adaptations

Adaptations to aerobic training include increased oxygen delivery to working muscles, higher rate of aerobic energy production and greater fat utilization.

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Cardio Training

Improved pulmonary capacity, decreased stroke volume and decreased myoglobin content is not a physiological function that improves with cardiovascular exercise training.

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Exercise Non-Responders

Exercise non-responders constitute less than 5% of exercise participants.

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Ventricular Hypertrophy

Left ventricular hypertrophy is not always a sign of disease.

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S.A.I.D. Principle

S.A.I.D. stands for Specific Adaptations to Imposed Demands meaning you are designing a training program to meet the specific needs of the athlete/sport.

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F.I.T.T. Principle

F.I.T.T. stands for Frequency, Intensity, Time, and Type.

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Aerobic Training Goal

For an experienced aerobic endurance athlete, increasing maximal heart rate is NOT an effective training target.

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What is Fartlek Training?

Fartlek training combines continuous training with short, intense bursts.

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Improved Aerobic Endurance

Factors that relate to improved aerobic endurance include all of the following EXCEPT Decreased pulmonary function.

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Study Notes

  • A hormone's effect on a tissue directly relates to the concentration of hormone in plasma and the number of receptors available.
  • The effect a hormone exerts on a tissue is directly related to the chemical structure of the hormone.
  • Prolactin and adrenocorticotropic hormone are hormones secreted by the anterior pituitary.
  • Catecholamines are secreted by the adrenal cortex.
  • Aldosterone is secreted by the adrenal cortex.
  • Plasma glucose maintenance during exercise is accomplished by liver gluconeogenesis and liver glycogenolysis.
  • Insulin and glucagon are slow-acting hormones that maintain plasma glucose.
  • Exercise alters glucose transport rate into muscles through GLUT 4 receptors.
  • Hormone solubility falls into two categories: water-soluble and lipid-soluble (steroid) hormones.
  • Aldosterone aids in sodium conservation and potassium excretion.
  • Epinephrine, glucagon, and cortisol can increase blood glucose levels.
  • Shortness of breath is termed Dyspnea.
  • Partial pressures require explanation.
  • The pulmonary system doesn't limit exercise performance in healthy young subjects during prolonged submaximal exercise (work rates (<90% VO2 max).
  • Intrapleural pressure is lower than atmospheric pressure.
  • Asthmatics experience difficulty exhaling.
  • Inspiration of the lungs occurs when the diaphragm contracts.
  • Deoxyhemoglobin isn't simply hemoglobin carrying carbon dioxide.
  • Central chemoreceptors are sensitive to increases in PO2 and pH decreases.
  • The volume of gas remaining in the lungs after a maximal expiration defines vital capacity.
  • Tidal volume x alveolar ventilation doesn't provide the amount of air moved in and out of lungs per minute.
  • The respiratory system balances acid-base during exercise. It removes H+ from the blood via the HCO3- reaction, promotes hyperventilation and CO2 exhalation, and stabilizes blood pH.
  • At rest, atmospheric pressure is 760 mm Hg.
  • Expiration is passive at rest.
  • Respiratory muscle fatigue happens during high-intensity exercise (>90% VO2 max).
  • Athletes performing active recovery between 800-meter sprints can reduce lactic acid levels quickly.
  • Aerobic endurance training adaptations include increased oxygen delivery to working muscles, a higher rate of aerobic energy production, and greater fat utilization as a fuel source.
  • Peak HR increase isn't a training goal for experienced aerobic endurance athletes.
  • Fartlek training combines other training types with easy and short/medium bursts.
  • Improved substrate utilization, enhanced exercise economy, and increased lactate threshold contribute to aerobic endurance but decreased pulmonary function does not.
  • S.A.I.D. (Specific Adaptations to Imposed Demands) designs training programs meeting an athlete's/sport's specific needs.
  • F.I.T.T. stands for Frequency, Intensity, Time, and Type.
  • Improved pulmonary capacity, decreased stroke volume, and decreased myoglobin content, are not physiological functions improved with cardiovascular exercise training.
  • Exercise non-responders account for under 5% of exercise participants.
  • Left ventricular hypertrophy isn't always a sign of disease.

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