Hormones and Endocrine System
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Questions and Answers

Which hormone directly opposes the effects of glucagon?

  • Triiodothyronine (T3)
  • Mineralocorticoids
  • Insulin (correct)
  • Oxytocin

Inhibiting hormones (IH) that regulate anterior pituitary function are primarily produced by which of the following?

  • Anterior Pituitary
  • Hypothalamus (correct)
  • Thyroid
  • Pancreas

What is the primary physiological effect during the alarm phase of the body's response to stress?

  • Conserve glucose, mobilize lipid reserves, conserve salts & water
  • Drainage of all energy reserves
  • Breakdown of organ system function, organ failure
  • Mobilize glucose energy reserves (correct)

Which hormone is synthesized and secreted by pinealocytes within the pineal gland?

<p>Melatonin (D)</p> Signup and view all the answers

What is the overall effect of insulin on blood glucose concentration?

<p>Decreased blood glucose (D)</p> Signup and view all the answers

Parathyroid hormone (PTH), crucial for calcium regulation, is produced by which specific cells?

<p>Parathyroid cells (C)</p> Signup and view all the answers

What is the primary effect of prolactin (PRL) on mammary glands?

<p>Milk production (D)</p> Signup and view all the answers

Which endocrine organ integrates neural and hormonal signals, exerting control over the pituitary gland and, consequently, many bodily functions?

<p>Pituitary Gland (B)</p> Signup and view all the answers

What type of stimulation primarily triggers the release of calcitonin from the thyroid?

<p>Humoral stimulation (C)</p> Signup and view all the answers

In a positive feedback loop involving two hormones, where hormone 1 stimulates the release of hormone 2, what happens to the levels of hormone 1 as hormone 2 levels increase?

<p>Increase (B)</p> Signup and view all the answers

Which gland releases catecholamines, such as epinephrine and norepinephrine, into circulation during times of stress?

<p>Adrenal gland (D)</p> Signup and view all the answers

Which tissues are primary targets for insulin action, facilitating glucose uptake and utilization?

<p>Anterior pituitary (C)</p> Signup and view all the answers

Which hormone opposes the effects of parathyroid hormone (PTH) and helps regulate calcium levels in the blood?

<p>Calcitonin (D)</p> Signup and view all the answers

Inhibiting hormones (IH) produced by the hypothalamus primarily target which gland?

<p>Anterior pituitary (A)</p> Signup and view all the answers

Which specific cells within the pancreas are primarily responsible for producing glucagon?

<p>Alpha cells (D)</p> Signup and view all the answers

Adrenocorticotropic hormone (ACTH) directly targets which endocrine gland to stimulate the release of cortisol?

<p>Adrenal gland (B)</p> Signup and view all the answers

How many distinct hormones are released into circulation by the anterior pituitary gland?

<p>7 (C)</p> Signup and view all the answers

Which specific phase of the general adaptation syndrome (GAS) is characterized by the body's attempt to counteract the effects of stress through the mobilization of resources?

<p>Resistance phase (A)</p> Signup and view all the answers

Which of the following is the primary stimulus for the release of growth hormone (GH) from the anterior pituitary?

<p>Hormonal stimulation (C)</p> Signup and view all the answers

Which cell type is exclusively found within the pineal gland that produces melatonin?

<p>Pinealocytes (D)</p> Signup and view all the answers

Beta cells, which are critical for glucose homeostasis through insulin production, are located in which endocrine organ?

<p>Pancreas (C)</p> Signup and view all the answers

Which gland secretes growth hormone (GH) into circulation?

<p>Anterior pituitary (A)</p> Signup and view all the answers

Which is primarily responsible for the production of releasing hormones (RH)?

<p>Hypothalamus (B)</p> Signup and view all the answers

Thyroid-stimulating hormone (TSH) acts specifically on which of the following?

<p>Thyroid (B)</p> Signup and view all the answers

In which major body region is the pineal gland located?

<p>Cranial (D)</p> Signup and view all the answers

What type of stimulation primarily causes the release of oxytocin?

<p>Neural stimulation (C)</p> Signup and view all the answers

Which of the following endocrine organs contains the Islets of Langerhans, known for housing cells that produce hormones regulating glucose levels?

<p>Pancreas (C)</p> Signup and view all the answers

In which endocrine organ are alpha cells located?

<p>Pancreas (A)</p> Signup and view all the answers

Which of the following cells are located in the thyroid?

<p>Follicular cells (C)</p> Signup and view all the answers

Which endocrine gland releases androgens into the circulation?

<p>Adrenal gland (B)</p> Signup and view all the answers

What is the primary physiological effect of melatonin on the human body?

<p>Feeling sleepy (C)</p> Signup and view all the answers

Which of the following stimulation causes the release of melatonin?

<p>Neural stimulation (C)</p> Signup and view all the answers

What is the predominant effect of triiodothyronine (T3) and thyroxine (T4) on the body's metabolic activity?

<p>Increased metabolic rate (B)</p> Signup and view all the answers

Prolactin (PRL) primarily targets which of the following?

<p>Mammary glands (A)</p> Signup and view all the answers

Adaptive immunity is present under which of the following circumstances?

<p>Only after presentation of a foreign antigen (D)</p> Signup and view all the answers

What is the term for the process by which B cells internalize and display an antigen?

<p>Sensitization (B)</p> Signup and view all the answers

Where does B cell differentiation get completed?

<p>Red bone marrow (C)</p> Signup and view all the answers

Once activated, what primary function do helper T cells perform?

<p>Activate B cells (A)</p> Signup and view all the answers

Which type of T cell is responsible for recognizing and binding to B cells during the adaptive immune response?

<p>Helper T cell (C)</p> Signup and view all the answers

Which immune response typically develops faster upon exposure to a pathogen?

<p>Secondary Immune Response (B)</p> Signup and view all the answers

What happens to electrolyte balance during the alarm phase of the general adaptation syndrome (GAS)?

<p>There is an increased excretion of electrolytes, potentially leading to imbalances. (C)</p> Signup and view all the answers

If Hormone A inhibits the secretion of Hormone B, and Hormone B stimulates the release of Hormone C, what would be the effect of increased concentration of Hormone A on the plasma concentration of Hormone C?

<p>The plasma concentration of Hormone C would decrease. (B)</p> Signup and view all the answers

During prolonged stress, cortisol is released. What is the consequence of long-term elevated levels of cortisol on immune function?

<p>Suppressed immune function, increasing susceptibility to infections. (C)</p> Signup and view all the answers

Which of the following is the most likely outcome of chronically elevated levels of growth hormone (GH)?

<p>Acromegaly, characterized by enlarged extremities and facial features. (B)</p> Signup and view all the answers

Which of the following best describes the relationship between the hypothalamus and the anterior pituitary gland?

<p>The hypothalamus releases releasing and inhibiting hormones into a portal system to regulate the anterior pituitary. (C)</p> Signup and view all the answers

If a patient has a tumor that causes excessive secretion of thyroid-stimulating hormone (TSH), what symptoms might you expect to see?

<p>Weight loss, anxiety, and increased heart rate. (D)</p> Signup and view all the answers

Which of the following mechanisms explains how the presence of thyroid hormones (T3 and T4) decreases TSH release?

<p>Negative feedback on both the hypothalamus and anterior pituitary gland. (D)</p> Signup and view all the answers

How would damage to the parathyroid glands impact blood calcium homeostasis, and what compensatory mechanisms might the body employ?

<p>Hypocalcemia; bones would release calcium through increased osteoclast activity. (D)</p> Signup and view all the answers

What is the expected outcome of administering a drug that enhances the sensitivity of target tissues to insulin in a patient with type 2 diabetes?

<p>Decreased blood glucose levels due to improved glucose uptake by cells. (C)</p> Signup and view all the answers

How do the effects of glucagon on liver cells contribute to maintaining blood glucose levels during fasting?

<p>Glucagon stimulates glycogenolysis and gluconeogenesis, increasing glucose release into the blood. (C)</p> Signup and view all the answers

In a scenario where a patient's adrenal glands are not producing sufficient cortisol, what would be the likely effect on ACTH levels, and why?

<p>ACTH levels would increase due to negative feedback inhibition being reduced. (B)</p> Signup and view all the answers

Which of the physiological consequences would you anticipate in an individual with a malfunctioning pineal gland?

<p>Disrupted sleep-wake cycles due to altered melatonin secretion (D)</p> Signup and view all the answers

What is the relationship between oxytocin and uterine contractions during childbirth, and how is this regulated?

<p>Oxytocin stimulates uterine contractions, regulated by positive feedback from cervical stretching. (C)</p> Signup and view all the answers

If a person is exposed to bright light late at night, what effect would you expect on their melatonin production and sleep cycle?

<p>Decreased melatonin production, potentially disrupting the sleep cycle. (A)</p> Signup and view all the answers

Which of the following explains the adaptive role of increased T3 and T4 production during exposure to cold temperatures?

<p>To increase metabolic rate and generate body heat. (B)</p> Signup and view all the answers

Which of the following processes is directly facilitated by prolactin's action on mammary gland cells?

<p>Increased synthesis of enzymes involved in milk production. (C)</p> Signup and view all the answers

How does the regulation of blood calcium levels differ between calcitonin and parathyroid hormone (PTH)?

<p>Calcitonin decreases blood calcium, while PTH increases blood calcium. (D)</p> Signup and view all the answers

What are the implications of damage to the hypophyseal portal system on endocrine function?

<p>Disrupted communication between the hypothalamus and anterior pituitary. (B)</p> Signup and view all the answers

In an individual experiencing chronic stress, how might the sustained release of cortisol affect the sensitivity of tissues to insulin?

<p>Decreased effectiveness of insulin, potentially leading to elevated blood glucose. (C)</p> Signup and view all the answers

What effect would a medication that blocks the action of growth hormone-releasing hormone (GHRH) have on an individual's growth?

<p>It would result in decreased growth due to reduced growth hormone secretion. (D)</p> Signup and view all the answers

What is the role of antigen-presenting cells (APCs) in initiating an adaptive immune response?

<p>Presenting processed antigens to T cells, activating them. (D)</p> Signup and view all the answers

How does the secondary immune response differ from the primary immune response in terms of speed and magnitude?

<p>The secondary response is faster and produces more antibodies. (C)</p> Signup and view all the answers

What is the fundamental difference in how B cells and T cells recognize antigens?

<p>T cells recognize antigens presented by MHC molecules, while B cells recognize free-floating antigens. (D)</p> Signup and view all the answers

What specific role do cytotoxic T cells play in clearing a viral infection??

<p>Recognizing and killing virus-infected cells by inducing apoptosis. (B)</p> Signup and view all the answers

How do regulatory T cells contribute to preventing autoimmune reactions?

<p>By suppressing the activity of other T cells and B cells. (B)</p> Signup and view all the answers

Which of the following explains the role of memory cells in long-term immunity?

<p>Memory cells differentiate into effector cells more rapidly upon subsequent exposure to the same antigen. (C)</p> Signup and view all the answers

How does the lymphatic system contribute to adaptive immunity by facilitating interactions between immune cells?

<p>By providing a site where lymphocytes can encounter antigens and interact with antigen-presenting cells. (A)</p> Signup and view all the answers

How does clonal selection contribute to the specificity of the adaptive immune response?

<p>By selectively activating and proliferating lymphocytes that express receptors specific to the encountered antigen. (A)</p> Signup and view all the answers

During B cell sensitization, what is the key event that prepares the B cell to respond to its specific antigen?

<p>Displaying the processed antigen on its surface bound to MHC II molecules. (C)</p> Signup and view all the answers

Which of the following describes the role of the thymus in T cell maturation?

<p>The thymus is where T cells undergo selection processes to ensure self-tolerance and immunocompetence. (A)</p> Signup and view all the answers

How is the activation of the complement system linked to both innate and adaptive immunity?

<p>The complement system can be activated directly by pathogens (innate) or by antibodies bound to pathogens (adaptive). (D)</p> Signup and view all the answers

How does inflammation represent a critical link between innate and adaptive immunity?

<p>Inflammation recruits immune cells and enhances antigen presentation, promoting adaptive immune responses. (A)</p> Signup and view all the answers

Which of the following is a key difference between active and passive immunity?

<p>Passive immunity involves the transfer of antibodies from another source, while active immunity involves the body producing its own antibodies. (A)</p> Signup and view all the answers

Why are vaccines considered a form of artificially acquired active immunity?

<p>Because they stimulate the body to produce its own antibodies and memory cells against a specific antigen. (A)</p> Signup and view all the answers

Why might certain pathogens, like viruses, evade the humoral (antibody-mediated) immune response?

<p>Because viruses replicate inside cells, making them inaccessible to circulating antibodies. (B)</p> Signup and view all the answers

How do primary lymphoid organs differ from secondary lymphoid organs in their role in the immune system?

<p>Primary lymphoid organs are where lymphocytes develop and mature, while secondary lymphoid organs are where immune responses are initiated. (B)</p> Signup and view all the answers

Flashcards

Insulin

Hormone that lowers blood glucose levels by promoting glucose uptake into cells.

Inhibiting Hormones (IH)

Hormones produced by the hypothalamus that inhibit the release of hormones from the anterior pituitary.

Alarm Phase

The initial stage of the body's stress response, characterized by mobilization of energy reserves, mainly glucose.

Melatonin

Hormone produced by the pinealocytes that influences sleep-wake cycles.

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Effect of Insulin

Lowers blood glucose levels.

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Parathyroid Cells

Cells in the parathyroid gland that produce parathyroid hormone (PTH).

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Effect of Prolactin (PRL)

Stimulates milk production in mammary glands.

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Hypothalamus

A brain region that regulates the pituitary gland and controls many bodily functions.

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Release of Calcitonin

The body's response to high calcium levels in the blood.

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Positive Feedback

In a positive feedback loop, hormone 1 levels increase as hormone 2 levels increase.

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Adrenal Gland

Glands that release catecholamines (epinephrine and norepinephrine) into circulation during stress.

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Insulin Targets

Organs targeted by insulin, including the liver, muscle, and fat cells.

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Calcitonin

Hormone that lowers blood calcium levels and opposes the action of parathyroid hormone (PTH).

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Inhibiting Hormones (IH) Target

The anterior pituitary is acted upon by the releasing hormones.

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Alpha Cells

Endocrine cells in the pancreas that produce glucagon, which raises blood glucose.

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Adrenocorticotropic hormone (ACTH) Target

Gland targeted by ACTH.

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Anterior Pituitary Hormones

Releases 7 hormones into circulation.

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Resistance Phase

The second stage of the general adaptation syndrome (GAS), where the body adapts to long-term stress.

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Hormonal Stimulation

Hormones regulate Growth Hormone (GH)

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Pinealocytes

Cells located in the pineal gland.

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Pancreas

Endocrine organ in the body that has islets of langerhans.

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Growth Hormone (GH)

The anterior pituitary releases growth hormone (GH)

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Releasing Hormones (RH)

Hormones that produce and release hormones from the hypothalamus.

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Thryoid-Stimulating Hormone (TSH) Target

The thyroid.

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Cranial

Region located in the brain.

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Oxytocin

Hormone released via neural stimulation

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Pancreas

The part of the organ responsible for endocrine production.

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Pancreas

Organ location of the alpha cells.

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Follicular cells

Cells that make up this tissue.

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adrenal gland

The part of the body that releases androgens into circulation.

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Effect of melatonin

Makes you sleepy.

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Neural stimulation

The cause of the stimulus to make melatonin.

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Effect of T3 and T4

Increases metabolic rate

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Mammary glands

The body part targeted by prolactin.

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Only after presentation of a foreign antigen

Where adaptive immunity is developed.

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Sensitization

B cells take in and present an antigen

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Red bone marrow

Where B cell differentiation is complete

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Helper T cells

Activate B cells

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Which T cell recognizes and binds to B cells?

Helper T-Cell

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Secondary Immune Response

Immune response activated by memory cells.

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Physical Barrier Function

Physical barriers keep antigens out of the body.

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Secondary Response

More antibodies are produced, a more robust and faster response.

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Thymus Secretion

Thymosins.

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B Cell Activation

Helper T Cell.

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Immunity at Birth

Innate Immunity.

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Self-Antigen Reaction

Autoimmune reaction.

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Cytotoxic T Cells

Identify and destroy infected or foreign cells.

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Volume in Lungs

Decreases.

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Air to Lung

Bronchus.

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Lungs Aid In

Pulmonary Lobules

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Diaphragm Muscles

Inspiratory.

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Tertiary Bronchi

Conduction.

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Skeletal Muscles Pull

up

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The Body Needs

Decrease.

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Outgoing Air

Bronchus, trachea, larynx.

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Study Notes

Hormones

  • Insulin antagonizes glucagon.
  • Inhibiting hormones (IH) are produced by the hypothalamus.
  • Melatonin is produced by pinealocytes.
  • The effect of insulin is decreased blood glucose.
  • Parathyroid hormone (PTH) is produced by parathyroid cells.
  • The effect of prolactin (PRL) is milk production.
  • The pituitary gland is the master endocrine gland.
  • Humoral stimulation causes the release of calcitonin.
  • In a positive feedback loop, as hormone 2 levels increase, hormone 1 levels increase.
  • Catecholamines are released into circulation by the adrenal gland.
  • Insulin targets the liver, muscle, and adipocytes.
  • Calcitonin antagonizes parathyroid hormone (PTH).
  • Inhibiting hormones (IH) target the anterior pituitary.
  • Glucagon is produced by alpha cells.
  • Adrenocorticotropic hormone (ACTH) targets the adrenal gland.
  • The anterior pituitary releases 9 hormones into circulation.
  • The resistance phase is the second phase of the general adaptation syndrome (GAS).
  • Hormonal stimulation causes the release of growth hormone (GH).
  • Pinealocytes are located in the pineal gland.
  • Beta cells are located in the pancreas.
  • Growth hormone (GH) is released into circulation by the anterior pituitary.
  • Releasing hormones (RH) are produced by the hypothalamus.
  • Thyroid-stimulating hormone (TSH) targets the thyroid.
  • The pineal gland is located in the cranial region.
  • Neural stimulation causes the release of oxytocin.
  • The pancreas contains islets of Langerhans.
  • Alpha cells are located in the pancreas.
  • Follicular cells are located in the thyroid.
  • Androgens are released into circulation by the adrenal gland.
  • The effect of melatonin is feeling sleepy.
  • Neural stimulation causes the release of melatonin.
  • The effect of triiodothyronine (T3) and thyroxine (T4) is increased metabolic rate.
  • Prolactin (PRL) targets the mammary glands.

Immunity

  • Adaptive immunity is present only after presentation of a foreign antigen.
  • Sensitization is the process by which B cells take in and present an antigen.
  • B cell differentiation is completed in the lymph node.
  • Helper T cells activate B cells.
  • Helper T cells recognize and bind to B cells.
  • The secondary immune response develops faster.
  • The lymphatic vessels transport lymphocytes.
  • Lymphatic vessels do no contribute to the maintenance of blood volume but they do Increase edema.
  • Innate immunity is present at birth.
  • Lymph nodes are located in the mucosal membranes and mediastinum.
  • A physical barrier in immunity keeps antigens out of the body.
  • The function of the spleen is to filter old red blood cells out of the blood, filter pathogens out of the lymph and monitor peripheral antigens.
  • Edema from the left arm is collected by the thoracic duct.
  • Hematopoiesis produces leukocytes, erythrocytes, and platelets.
  • Lymphatic vessels transport lymphocytes and removes and filter antigens from peripheral tissues.
  • Lymphoid stem cells in the bone marrow give rise to T cells.
  • The thymus plays a role in the development of B-cells.
  • Cytotoxic T cells identify infected or foreign cells and destroy them.
  • Appendicitis is inflammation of the appendix.
  • Phagocytes create an inhospitable environment for foreign cells.
  • The number of antibodies produced in a secondary response is greater compared to a primary response.
  • Neither blood nor lymph capillaries have valve openings. Only lymphatic capillaries do
  • An autoimmune reaction is when the body generates an immune reaction against a self-antigen.
  • The thymus creates and releases thymosins.
  • Once a T cell is activated; hemostasis occurs.
  • Lymphopoiesis occurs once a T cell is activated.
  • Helper T Cells are required to be present in order for B cells to become activated.
  • Immune surveillance alerts surrounding tissue of local infection.
  • Lymphatic vessels transport fluid from peripheral tissue to veins.
  • Lymphatic vessels begin in capillary beds and end in the venous system.
  • Interferons create an inhospitable environment for foreign cells.
  • A secondary lymphatic tissue monitors antigens.

Respiratory System

  • The upper respiratory system includes the Nasopharynx, Nasal cavity, Larynx and External nare.

  • The primary (main) bronchi aid in respiration.

  • The number of nasal conchae located in the left side of the nose is Four.

  • When air passes through the respiratory structures during INHALATION The correct order is: Primary bronchus, Secondary bronchus, Tertiary bronchus, Terminal bronchiole and Respiratory bronchiole.

  • Bronchus, trachea and larynx are the correct order of the respiratory tract as air passes through them OUT of the body.

  • The tertiary (segmental) bronchi assist in respiration.

  • Nasal conchae are part of the lower respiratory system.

  • The total amount of air in the lungs after forceful inhalation is vital capacity VC; and a forceful exhalation decreases lung volume.

  • During quiet breathing exhalation; passive muscle recoil is involved. The movement of air into and out of the lungs is ventilation.

  • The parts of the respiratory tract listed in the correct order of air passing through them as it travels OUT of the body: Bronchus, trachea, larynx.

  • Nasal meatus is located in the craniofacial region.

  • The larynx is part of the lower respiratory system.

  • Articulation is the manipulation of outgoing sounds by structures in the oral cavity to create speech.

  • The nasal meatus is located in the craniofacial region.

  • The external nare is part of the upper respiratory system.

  • During inhalation, as air passes through the nasopharynx, it will enter the oropharynx.

  • Hypoventilation is a lower-than-normal breathing rate.

  • During forced breathing, exhalation involves both active contractions and passive recoil.

  • The function of the external nares is to provide an entrance into and exit out of the body for air.

  • The epithelial covering of the larynx is a mucosal membrane.

  • The primary (main) bronchus delivers air into the left lung.

  • The thyroid cartilage is commonly referred to as the 'Adam's Apple'.

  • The pulmonary lobules aid in respiration.

  • The epithelial covering of the laryngopharynx is stratified squamous epithelium.

  • The epiglottis is made of cartilage tissue.

  • When expiratory muscles are activated, the volume in the lungs decreases.

  • The function of the trachea is to trap particles in the incoming air before they enter the lungs.

  • There are three nasal conchae located in the left side of the nose.

  • The trachea is part of the lower respiratory system.

  • The primary (main) bronchi aid in conduction.

  • The correct order that air passes through the respiratory structures during INHALATION is 1, 3, 5, 4, 2 (Primary bronchus, Secondary bronchus, Tertiary bronchus, Terminal bronchiole, Respiratory bronchiole).

  • The parts of the respiratory tract listed in the correct order of air passing through them as it travels OUT of the body: Bronchus, trachea, larynx.

  • The diaphragm belongs to inspiratory muscles

  • The tertiary (segmental) bronchi aid in conduction.

  • During inhalation, the pressure in the lungs is less than the pressure of air outside of the body.

  • IRV + ERV + TV = VC (Vital Capacity).

  • During quiet breathing, exhalation involves passive muscle recoil.

  • The correct order that air passes through the portions of the pharynx during exhalation 1, 3, 2 (Laryngopharynx, Oropharynx, Nasopharynx).

  • Ventilation is the movement of air into and out of the lungs.

  • In order to cause inhalation, skeletal muscles pull up on the thoracic cage.

  • The total amount of air that can be found in the lungs after a forceful inhalation is called the total lung capacity (TLC).

  • Adding together the tidal volume (TV), inspiratory reserve volume (IRV), expiratory reserve volume (ERV), and residual volume (RV) provides the value for the total lung capacity (TLC).

  • In order to cause exhalation, the body needs to decrease lung volume.

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Description

Overview of hormones, their production sites, and their effects on the body. Key hormones discussed include insulin, glucagon, melatonin, parathyroid hormone, and prolactin. Also covers the roles of glands such as the pituitary, pineal, and adrenal glands.

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